Analysis of cancer lymph node metastasis using iinformation science technology.

• Project/Area Number: 20591489
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Radiation science
• Research Institution: Hokkaido University
• Principal Investigator: ONIMARU Rikiya Hokkaido University, 大学院・医学研究科, 講師 (80374461)
• Co-Investigator(Kenkyū-buntansha): MIZUTA Masahiro 北海道大学, 情報基盤センター, 教授 (70174026)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2008: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
• Keywords: 放射線治療 / リンパ節転移 / データ・マイニング / 頭頚部癌 / 総治療期間 / 再照射 / 情報学的手法 / 強度変調放射線治療 / 1回線量

Research Abstract

(1) Analysis of cervical lymph node metastasis of head and neck cancer.
We evaluated patterns of lymph node metastasis. We found clinically meaningful rules of patterns. It may be suggested that this method is hopeful for investigation.
(2) Analysis of effect of overall treatment time on treatment results of T1N0 glottic carcinoma.
We conducted retrospective analysis of T1N0 glottic carcinoma. It is suggested that OTT is important factor for LCR.
(3) Analysis of reirradiation for recurrent nasopharyngeal carcinoma.
We conducted retrospective analysis of reirradiation for recurrent nasopharyngeal carcinoma. Reirradiation may be one of the treatment for recurrent nasopharyngeal carcinoma.

Research Products

• [Journal Article] Radiotherapy for glottic T1N0 carcinoma with slight hypofractionation and standard overall treatment time: importance of overall treatment time. (2011)
  • Author(s): Onimaru R, Hasegawa M, Yasuda K, Homma A, Oridate N, Fukuda S, Shirato H.
  • Journal Title: Japanese Journal of Clinical Oncology. Vol 41 Pages: 103-109
  • Peer Reviewed
• [Journal Article] Radiotherapy for glottic T1N0 carcinoma with slight hypofractionation and standard overall treatment time : importance of overall treatment time. (2011)
  • Author(s): Onimaru R, Hasegawa M, Yasuda K, Homma A, Oridate N, Fukuda S, Shirato H.
  • Journal Title: Japanese Journal of Clinical Oncology Volume: 41 Pages: 103-109
  • Peer Reviewed
• [Journal Article] 区間値関数データに対する主成分分析法の提案 (2010)
  • Author(s): 池田智康、小宮由里子、南弘征、水田正弘
  • Journal Title: 応用統計学 39巻 Pages: 21-33
  • NAID: 10026049130
  • Peer Reviewed
• [Journal Article] 分布値データに対する階層的シンボリッククラスタリングについて (2010)
  • Author(s): 片山琴絵, 南弘征, 水田正弘
  • Journal Title: 計算機統計学 22巻 Pages: 83-89
  • NAID: 110007619730
  • Peer Reviewed
• [Journal Article] On Multiple-Case Diagnostics in Linear Subspace Method (2010)
  • Author(s): Kuniyoshi Hayashi, Hiroyuki Minami, Masahiro Mizuta
  • Journal Title: COMPSTAT'2010 19巻 Pages: 22-27
  • Peer Reviewed
• [Journal Article] 区間値関数データに対する主成分分析法の提案 (2010)
  • Author(s): 池田智康、小宮由里子、南弘征、水田正弘
  • Journal Title: 応用統計学 Volume: 39-1 Pages: 21-33
  • NAID: 10026049130
  • Peer Reviewed
• [Journal Article] 分布値データに対する階層的シンボリッククラスタリングについて (2010)
  • Author(s): 片山琴絵, 南弘征, 水田正弘
  • Journal Title: 計算機統計学 Volume: 22-2 Pages: 83-89
  • NAID: 110007619730
  • Peer Reviewed
• [Journal Article] On Multiple-Case Diagnostics in Linear Subspace Method (2010)
  • Author(s): Kuniyoshi Hayashi, Hiroyuki Minami, Masahiro Mizuta
  • Journal Title: COMPSTAT'2010 Volume: 19 Pages: 22-27
  • Peer Reviewed
• [Journal Article] 北海道大学病院での頭頚部癌に対する強度変調放射線治療の成績 (2009)
  • Author(s): 鬼丸力也、長谷川雅一, 他
  • Journal Title: 頭頚部癌 35巻 Pages: 245-249
• [Journal Article] 強度変調放射線治療(intensity modulated radiotherapy ; IMRT) (2009)
  • Author(s): 鬼丸力也、木下留美子
  • Journal Title: ENTONI 103巻 Pages: 14-20
• [Journal Article] 北海道大学病院での頭頚部癌に対する強度変調放射線治療の成績 (2009)
  • Author(s): 鬼丸力也, 長谷川雅一, 他
  • Journal Title: 頭頚部癌 35 Pages: 245-249
• [Journal Article] 強度変調放射線治療(intensity modulated radiotherapy ; IMRT) (2009)
  • Author(s): 鬼丸力也, 木下留美子
  • Journal Title: ENTONI 103 Pages: 14-20
• [Journal Article] ランダム関数の関数主要点と関数クラスタリングについて (2009)
  • Author(s): 清水信夫, 水田正弘
  • Journal Title: 計算機統計学 21 Pages: 1-13
  • NAID: 110007333718
  • Peer Reviewed
• [Journal Article] 相対射影追跡法の関数データへの拡張 (2009)
  • Author(s): 弘新太郎, 南弘征, 水田正弘
  • Journal Title: 計算機統計学 21 Pages: 15-28
  • NAID: 110007333717
  • Peer Reviewed
• [Journal Article] ランダム関数の関数主要点と関数クラスタリングについて (2009)
  • Author(s): 清水信夫, 水田正弘
  • Journal Title: 計算機統計学 21(1-2) Pages: 1-13
  • NAID: 110007333718
  • Peer Reviewed
• [Journal Article] 相対射影追跡法の関数データへの拡張 (2009)
  • Author(s): 弘新太郎, 南弘征, 水田正弘
  • Journal Title: 計算機統計学 21(1-2) Pages: 15-28
  • NAID: 110007333717
  • Peer Reviewed
• [Journal Article] Clinical Outcomes of Stereotactic Body Radiotherapy for Small Lung Lesions Clinically Diagnosed as Primary Lung Cancer on Radiologic Examination (2009)
  • Author(s): Inoue T, Shimizu S, Onimaru R, Takeda A, Onishi H, Nagata Y, Kimura T, Karasawa K, Arimoto T, Hareyama M, Kikuchi E, Shirato H
  • Journal Title: Int J Radiat Oncol Biol Phys (in press)
  • Peer Reviewed
• [Journal Article] Functional Principal Points and Functional Cluster Analysis. (2008)
  • Author(s): Nobuo Shimizu, Masahiro Mizuta
  • Journal Title: Computational Intelligence Paradigms,: Innov. Applications SCI 137 Pages: 149-165
  • Peer Reviewed
• [Journal Article] Principal Component Analysis for Modal Interval-Valued Data (2008)
  • Author(s): Atsushi Hamada, Hiroyuki Minami, Masahiro Mizuta
  • Journal Title: IASC2008 Vol1 Pages: 512-519
  • Peer Reviewed
• [Journal Article] An Extension of Functional PCA to Interval-Valued Functional Data (2008)
  • Author(s): 池田智康, 小宮由里子, 南弘征, 水田正弘
  • Journal Title: IASC2008 Vol1 Pages: 640-647
  • NAID: 10026049130
  • Peer Reviewed
• [Journal Article] Auto Regression Analysis for Symbolic Distribution-Valued Data (2008)
  • Author(s): Kazuma Takahashi, Yuriko Komiya, Hiroyuki Minami, Masahiro Mizuta
  • Journal Title: IASC2008 Vol1 Pages: 1479-1483
  • Peer Reviewed
• [Journal Article] Real-time tumor-tracking radiotherapy for adrenal tumors (2008)
  • Author(s): KatohN, Onimaru R, SakuharaY, Abo D, Shimizu S, Taguchi H, Watanabe Y, Shinohara N, Ishikawa M, Shirato H
  • Journal Title: Radiother Oncol 87 Pages: 418-424
  • Peer Reviewed
• [Journal Article] Functional Principal Points and Functional Cluster Analysis (2008)
  • Author(s): Nobuo Shimizu and Masahiro Mizuta
  • Journal Title: Computational Intelligence Paradigms, : Innov. Applications SCI137 Pages: 149-165
  • Peer Reviewed
• [Journal Article] Principal Component Analysis for Modal Interval-Valued Data (2008)
  • Author(s): Atsushi Hamada, Hiroyuki Minami, Masahiro Mizuta
  • Journal Title: IASC2008 1 Pages: 512-519
  • Peer Reviewed
• [Journal Article] An Extension of Functional PCA to Interval-Valued Functional Data (2008)
  • Author(s): Tomoyasu Ikeda, Yuriko Komiya, Hiroyuki Minami, Masahiro Mizuta
  • Journal Title: IASC2008 1 Pages: 640-647
  • NAID: 10026049130
  • Peer Reviewed
• [Journal Article] Auto Regression Analysis for Symbolic Distribution-Valued Data (2008)
  • Author(s): Kazuma Takahashi, Yuriko Komiya, Hiroyuki Minami, Masahiro Mizuta
  • Journal Title: IASC2008 1 Pages: 1479-1483
  • Peer Reviewed
• [Presentation] 放射線治療を受けた舌癌患者のリンパ節転移・再発のパターン (2010)
  • Author(s): 鬼丸力也、安田耕一、西川昇、白土博樹
  • Organizer: 第23回日本放射線腫瘍学会
  • Place of Presentation: 東京
  • Year and Date: 2010-11-19
• [Presentation] 放射線治療を受けた舌癌患者のリンパ節転移・再発のパターン (2010)
  • Author(s): 鬼丸力也、安田耕一、西川昇、白土博樹
  • Organizer: 日本放射線腫瘍学会第23回学術大会
  • Place of Presentation: 東京ベイ舞浜ホテルクラブリゾート(千葉県)
  • Year and Date: 2010-11-19
• [Presentation] 声門癌(T1N0)に対する北大病院での放射線治療成績 (2010)
  • Author(s): 鬼丸力也、安田耕一、長谷川雅一、白土博樹弘樹
  • Organizer: 第123回日本医学放射線学会北日本地方会
  • Place of Presentation: 仙台
  • Year and Date: 2010-10-15
• [Presentation] 声門癌(T1N0)に対する北大病院での放射線治療成績 (2010)
  • Author(s): 鬼丸力也、安田耕一、長谷川雅一、白土博樹
  • Organizer: 第123 回日本医学放射線学会北日本地方会
  • Place of Presentation: 艮陵会館(宮城県)
  • Year and Date: 2010-10-15
• [Presentation] A Knowledge Engineering applied Symbolic Data Analysis. (2010)
  • Author(s): Hiroyuki Minami, Masahiro Mizuta
  • Organizer: 34th Annual Conference of the German Classification Society (GfKl) and International Symposium on the Data Analysis Interface
  • Place of Presentation: Karlsruhe 大学 (Karlsruhe)
  • Year and Date: 2010-07-23
• [Presentation] Analysis of Distribution Valued Data and its Applications (2010)
  • Author(s): Masahiro Mizuta
  • Organizer: 34th Annual Conference of the German Classification Society (GfKl) and International Symposium on the Data Analysis Interface
  • Place of Presentation: Karlsruhe 大学 (Karlsruhe)(招待講演)
  • Year and Date: 2010-07-23
• [Presentation] Analysis of Distribution Valued Data and its Applications (2010)
  • Author(s): Masahiro Mizuta
  • Organizer: 34th Annual Conference of the German Classification Society (GfKI) and International Symposium on the Data Analysis Interface
  • Place of Presentation: Karlsruhe大学(Karlsruhe)トイツ 招待講演
  • Year and Date: 2010-07-23
• [Presentation] A Knowledge Engineering applied Symbolic Data Analysis (2010)
  • Author(s): Hiroyuki Minami, Masahiro Mizuta
  • Organizer: 34th Annual Conference of the German Classification Society (GfKI) and International Symposium on the Data Analysis Interface
  • Place of Presentation: Karlsruhe大学(Karlsruhe)トイツ
  • Year and Date: 2010-07-23
• [Presentation] Inference of user preferences from logging GPS data. (2010)
  • Author(s): Masanori Fujita, Shinji Morishita, Hiroyuki Minami, Masahiro Mizuta
  • Organizer: 34th Annual Conference of the German Classification Society (GfKl) and International Symposium on the Data Analysis Interface
  • Place of Presentation: Karlsruhe 大学 (Karlsruhe)
  • Year and Date: 2010-07-22
• [Presentation] Inference of user preferences from logging GPS data (2010)
  • Author(s): Masanori Fujita, Shinji Morishita, Hiroyuki Minami, Masahiro Mizuta
  • Organizer: 34th Annual Conference of the German Classification Society (GfKI) and International Symposium on the Data Analysis Interface
  • Place of Presentation: Karlsruhe大学(Karlsruhe)トイツ
  • Year and Date: 2010-07-22
• [Presentation] Interval Data and Distribution Data (2010)
  • Author(s): Masahiro Mizuta
  • Organizer: The 1st International Conference for Industrial Statistics and Bioinformatics Current Issues in Industrial Statistics and Bioinformatics
  • Place of Presentation: Chung-Ang University(Seoul)(招待講演)
  • Year and Date: 2010-06-29
• [Presentation] Interval Data and Distribution Data (2010)
  • Author(s): Masahiro Mizuta
  • Organizer: The 1st International Conference for Industrial Statistics and Bioinformatics Current Issues in Industrial Statistics and Bioinformatics
  • Place of Presentation: Chung-Ang University(Seoul) 招待講演
  • Year and Date: 2010-06-29
• [Presentation] 上咽頭癌再発症例に対する再照射例の検討 (2010)
  • Author(s): 鬼丸力也、白土博樹、安田耕一、西川昇、米山里奈、本間明宏、折館伸彦、福田諭
  • Organizer: 第122回日本医学放射線学会北日本地方会
  • Place of Presentation: 山形
  • Year and Date: 2010-06-25
• [Presentation] 上咽頭癌再発症例に対する再照射例の検討 (2010)
  • Author(s): 鬼丸力也、安田耕一、西川昇、米山理奈、本間明宏、折舘信彦, 他
  • Organizer: 第122回日本医学放射線学会北日本地方会
  • Place of Presentation: ホテルキャッスル山形(山形県)
  • Year and Date: 2010-06-25
• [Presentation] Discriminant Analysis for Distribution Valued Data (2010)
  • Author(s): Masahiro Mizuta, Hiroyuki Minami
  • Organizer: The 30th International Symposium of Forecasting
  • Place of Presentation: Manchester Grand Hyatt, (San Diego)
  • Year and Date: 2010-06-23
• [Presentation] Discriminant Analysis for Distribution Valued Data (2010)
  • Author(s): Masahiro Mizuta, Hiroyuki Minami
  • Organizer: The 30th International Symposium of Forecasting
  • Place of Presentation: Manchester Grand Hyatt, (San Diego)米国
  • Year and Date: 2010-06-23
• [Presentation] Adaptive Sensitivity Analysis and its Simulation Study The Spring Conference (2010)
  • Author(s): Kuniyoshi HAYASHI, Hiroyuki MINAMI, Masahiro MIZUTA
  • Organizer: The Korean Statistical Society
  • Place of Presentation: Statistical Center(Daejeon)
  • Year and Date: 2010-05-22
• [Presentation] Case Study on Trends of Consumers from House Card Data The Spring Conference (2010)
  • Author(s): Naoki Kishimoto, Yuriko Komiya, Hiroyuki Minami, Masahiro Mizuta
  • Organizer: The Korean Statistical Society
  • Place of Presentation: Statistical Center(Daejeon)
  • Year and Date: 2010-05-22
• [Presentation] An Extension of Correspondence Analysis for Functional Data The Spring Conference (2010)
  • Author(s): Kazuya Kondo, Kenji Toyoda, Hiroyuki Minami, Masahiro Mizuta
  • Organizer: The Korean Statistical Society
  • Place of Presentation: Statistical Center(Daejeon)
  • Year and Date: 2010-05-22
• [Presentation] Adaptive Sensitivity Analysis and its Simulation Study (2010)
  • Author(s): Kuniyoshi HAYASHI, Hiroyuki MINAMI, Masahiro MIZUTA
  • Organizer: The Spring Conference, The Korean Statistical Society
  • Place of Presentation: Statistical Center(Daejeon)
  • Year and Date: 2010-05-22
• [Presentation] Case Study on Trends of Consumers from House Card Data (2010)
  • Author(s): Naoki Kishimoto, Yuriko Komiya, Hiroyuki Minami, Masahiro Mizuta
  • Organizer: The Spring Conference, The Korean Statistical Society
  • Place of Presentation: Statistical Center(Daeieon)韓国
  • Year and Date: 2010-05-22
• [Presentation] An Extension of Correspondence Analysis for Functional Data (2010)
  • Author(s): Kazuya Kondo, Kenji Toyoda, Hiroyuki Minami, Masahiro Mizuta
  • Organizer: The Spring Conference, The Korean Statistical Society
  • Place of Presentation: Statistical Center(Daejeon)韓国
  • Year and Date: 2010-05-22
• [Presentation] 関数データ解析法とその応用 (2009)
  • Author(s): 水田正弘
  • Organizer: 応用統計学会2009年度年会 特別講演
  • Place of Presentation: 東京都、統計数理研究所
  • Year and Date: 2009-08-01
• [Presentation] 北海道大学病院での頭頚部癌に対する強度変調放射線治療の成績 (2009)
  • Author(s): 鬼丸力也、長谷川雅一、安田耕一、木下留美子、白土博樹、本間明宏、折舘伸彦、福田諭
  • Organizer: 日本頭頚部癌学会第33回日本頭頚部癌学会
  • Place of Presentation: 札幌
  • Year and Date: 2009-06-12
• [Presentation] 北海道大学病院での頭頚部癌に対する強度変調放射線治療の成績 (2009)
  • Author(s): 鬼丸力也, 他
  • Organizer: 第33回日本頭頚部癌学会総会
  • Place of Presentation: 札幌、ロイトン札幌
  • Year and Date: 2009-06-12
• [Presentation] 低酸素イメージング(FMISO-PET)の放射線治療への応用 (2009)
  • Author(s): 安田耕一、長谷川雅一、鬼丸力也、白土博樹、岡本祥三、玉木長良
  • Organizer: 第35回北海道頭頚部腫瘍研究会
  • Place of Presentation: 札幌、教育文化会館
  • Year and Date: 2009-02-14
• [Presentation] Multidimensional scaling - when the dissimilarity data are distributions. (2008)
  • Author(s): Masahiro Mizuta
  • Organizer: Statistical Computation and Visualization 2008
  • Place of Presentation: Academia Sinica, Taipei, Taiwan(Invited Lecture)
  • Year and Date: 2008-12-03
• [Presentation] Multidimensional scaling-when the dissimilarity data are distributions (2008)
  • Author(s): Masahiro Mizuta
  • Organizer: Statistical Computation and Visualization 2008
  • Place of Presentation: Academia Sinica, Taipei, Taiwan(Invited Lecture)
  • Year and Date: 2008-12-03
• [Presentation] New Data Frames for Data Analysis. (2008)
  • Author(s): Masahiro Mizuta
  • Organizer: 2008 Korea-Japan Statistics Conference of Young Researchers
  • Place of Presentation: Korea University, Seoul, Korea(Invited Lecture)
  • Year and Date: 2008-07-10
• [Presentation] New Data Frames for Data Analysis (2008)
  • Author(s): Masahiro Mizuta
  • Organizer: 2008 Korea-Japan Statistics Conference of Young Researchers
  • Place of Presentation: Korea University, Seoul, Korea(Invited Lecture)
  • Year and Date: 2008-07-10
• [Presentation] The impact of 18F-fluoromisonidazole PET for HE cancer and the applying for IMRT (2008)
  • Author(s): 安田耕一、長谷川雅一、鬼丸力也、白土博樹、他
  • Organizer: 第119回日本医学放射線学会北日本地方会
  • Place of Presentation: 仙台、フォレスト仙台
• [Presentation] A New Positron Emission Tomography with Semiconductor Detectors for Target Volume Delineation and Radiotherapy Treatment Planning in Patients with Nasopharyngeal Carcinoma (2008)
  • Author(s): Katoh N, Shiga T, Hasegawa M, Onimaru R, Yasuda K, Shimizu S, Gerard B, Ishikawa M, Tamaki N, Shirato H
  • Organizer: The 50th Annual Meeting, American Society for Therapeutic Radiology and Oncology
  • Place of Presentation: Boston, Boston Convention and Exhibition Center