Introduction of humanβ-defensin-3 and human cathelicidine antimicrobial peptide-18 into cultured human skin cells
Project/Area Number |
20591534
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
General surgery
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Research Institution | Tokai University |
Principal Investigator |
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Research Collaborator |
ANDO Kiyoshi 東海大学, 医学部, 教授 (70176014)
UMEZAWA Kazuo 東海大学, 医学部, 講師 (30349344)
SUZUKI Yousuke 東海大学, 医学部, 講師 (90459454)
|
Project Period (FY) |
2008 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | 移植・再生医療 / 培養皮膚 / 抗菌ペプチド / ウイルスベクター / LL37 / hBD3 / 再生医療 / hCAP18 |
Research Abstract |
Humanβ-defensin-3(hBD3) gene and human cathelicidine antimicrobial peptide-18(hCAP18/LL37) gene were introduced into cultured human skin cells simultaneously by a recombinant adenovirus vector. The virus infected cells secreted both hBD3 and hCAP18, a pro-peptide of LL37.
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Report
(6 results)
Research Products
(11 results)
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[Journal Article] Introduction of humanβ-defensin-3 into cultured human keratinocytes and fibroblasts by infection of a recombinant adenovirus vector2011
Author(s)
Suzuki Y, Inokuchi S, Takazawa K, Umezawa K, Saito T, Kidokoro M, Tanaka M, Matsuzawa H, Inoue S, Tsuchiya I, Ando K
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Journal Title
Burns
Volume: 37(1)
Pages: 109-16
Related Report
Peer Reviewed
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[Journal Article] Introduction of human β-defensin-3 into cultured human keratinocytes and fibroblasts by infection of a recombinant adenovirus vector.2011
Author(s)
Suzuki Y, Inokuchi S, Takazawa K, Umezawa K, Saito T, Kidokoro M, Tanaka M, Matsuzawa H, Inoue S, Tuchiya I, Ando K.
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Journal Title
Burns. 37(1)
Pages: 109-116
Related Report
Peer Reviewed
-
[Journal Article] Introduction of human β-defensin-3 into cultured human keratinocytes and fibroblasts by infection of a recombinant adenovirus vector2011
Author(s)
Suzuki Y, Inokuchi S, Takazawa K, Umezawa K, Saito T, Kidokoro M, Tanaka M, Matsuzawa H, Inoue S, Tachiya I, Ando K.
-
Journal Title
Burns.
Volume: 37(1)
Pages: 109-16
Related Report
Peer Reviewed
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