Development of new treatment of sepsis with adiponectin
| Project/Area Number |
20591544
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General surgery
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| Research Institution | Shiga University of Medical Science |
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Principal Investigator |
YAMAMOTO Hiroshi Shiga University of Medical Science, 医学部, 助教 (00283557)
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| Co-Investigator(Renkei-kenkyūsha) |
TANI Tohru 滋賀医科大学, 医学部, 教授 (20179823)
MAEDA Kazuhisa 大阪大学, 医学系研究科, 助教 (60397750)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | 外科 / 感染症 / 生理活性 / 臨床 / アディポネクチン / 感染予測 / エンドトキシン / 胃癌 / adiponectin / sepsis / cytokine / hepatic injury / 敗血症 / KOマウス / PPARγ |
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| Research Abstract |
The role of adiponectin in sepsis has been revealed by using adiponectin KO mouse. In the clinical study, adiponectin ratio has been shown to be an useful marker to predict the postoperative infection.
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Report
(4 results)
Research Products
(30 results)
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[Presentation] 消化器外科周術期の血中微生物構成成分の変動2009
Author(s)
清水智治, 遠藤善裕, 目片英治, 山本寛, 村田聡, 塩見尚礼, 仲成幸, 森毅, 赤堀浩也, 田畑貴久, 山口剛, 来見良誠, 谷徹
Organizer
第34回日本外科系連合学会学術集会・ワークショップ
Related Report
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