A basic study on the effect of bariatric surgeries to improve type 2 diabetes : Toward days to cure severe diabetes with surgery.
| Project/Area Number |
20591586
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Digestive surgery
|
|---|
| Research Institution | Tohoku University |
|---|
Principal Investigator |
SHIBATA Chikashi Tohoku University, 大学院・医学系研究科, 准教授 (30455779)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
柴田 近 東北大学, 大学院・医学系研究科, 准教授 (30270804)
木内 誠 東北大学, 病院, 助教 (90422146)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
|---|
| Keywords | 消化管運動 / 消化管ホルモン / 膵液 / 胆汁 / 糖尿病 / 肥満 / metabolic surgery / 外科 / 生理学 / 動物 / 動体機能利用 / 生体機能利用 |
|---|
| Research Abstract |
In dogs, we studied the effect of bile and/or pancreatic juice diversion into the ileum on gastrointestinal motility and hormone secretion. Fasted and postprandial upper gastrointestinal motility was decreased in dogs with bile and bile/pancreatic juice diversions. Plasma levels of gastric inhibitory polypeptide were decreased in digs with pancreatic juice and bile/pancreatic juice diversions. Plasma levels of peptide tyrosine-tyrosine were decreased in digs with bile diversion.
|
Report
(4 results)
Research Products
(9 results)
