| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Research Abstract |
When the appearance of SOX4 was a strong positivity by inducing SOX4 tocolon cancer cell, it turned out that the shift of beta-catenin to the nucleus was changed, and the disease stage advanced, and the prognosis was poor. In the examination for microRNA signature, it was thought that the progress of colon cancer had happened because of strength of signature. It was suggested that SOX4 controls the Wnt signaling by beta-catenin, and was thought the possibility of taking part in generating and making of colon cancer. It was suggested that there was a possibility of the one by the introduction of microRNA as a vaccine therapy of SOX4.
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