New preservation solution for liver transplantation
| Project/Area Number |
20591602
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Digestive surgery
|
|---|
| Research Institution | Tokyo Medical and Dental University |
|---|
Principal Investigator |
KUDOU Atsushi Tokyo Medical and Dental University, 医学部附属病院, 助教 (20376734)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
ARII Shigeki 東京医科歯科大学 (70431905)
有井 滋樹 東京医科歯科大学, 大学院・医歯学総合研究科, 教授 (50151171)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2010: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
|
|---|
| Keywords | 冷保存虚血再還流障害 / 肝移植 / 保存液 / Mrp2 / 内在化 / 微小循環障害 / 生体内異物解毒 / 脂肪肝 / 虚血再灌流障害 / 臓器保存液 / Kupffer細胞活性化 / 冷保存障害 / 再還流障害 / 肝細胞機能保存 / 低酸素 / グリチルリチン |
|---|
| Research Abstract |
Mrp2-dependent decreased bile flow in the post-warm ischemic rat liver. Severe Macrovesicular Fatty Liver Decreases PPARγ-dependent Organic Anion Transports through Mrp2 in Rats. Preservation Solutions Alter Mrp2-Dependent Bile Flow in Cold Ischemic Rat Livers.
|
Report
(4 results)
Research Products
(23 results)
-
[Journal Article] Crucial role of impaired Kupffer cell phagocytosis on the decreased Sonazoid -enhanced echogenicity in a liver of a nonalchoholic steatohepatitis rat model.2010
Author(s)
Yoshikawa S, Iijima H, Saito M, Tanaka H, Imanishi H, Yoshimoto N, Yoshimoto T, Futatsugi-Yumikura S, Nakanishi K, Tsujimura T, Nishigami T, Kudo A, Arii S, Nishiguchi S.
-
Journal Title
Hepatol Res. 40(8)
Pages: 823-831
NAID
Related Report
-
-
-
-
[Journal Article] Crucial role of impaired Kupffer cell phagocytosis on the decreased Sonazoid-enhanced echogenicity in a liver of a nonalchoholic steatohepatitis rat model.2010
Author(s)
Yoshikawa S, Iijima H, Saito M, Tanaka H, Imanishi H, Yoshimoto N, Yoshimoto T, Futatsugi-Yumikura S, Nakanishi K, Tsujimura T, Nishigami T, Kudo A, Arii S, Nishiguchi S.
-
Journal Title
Hepatol Res.
Volume: 40(8)
Pages: 823-831
NAID
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
