• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

The Dendritic Based Immunotherapy for Refractory Pancreatic Cancer

Research Project

Project/Area Number 20591636
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Digestive surgery
Research InstitutionFukushima Medical University

Principal Investigator

KENJO Akira  Fukushima Medical University, 医学部, 助教 (40305355)

Co-Investigator(Kenkyū-buntansha) SAITO Takuro  福島県立医科大学, 医学部, 医監兼教授 (20305361)
SATOH Yoshihiro  福島県立医科大学, 医学部, 博士研究員 (60347218)
KIMURA Takashi  福島県立医科大学, 医学部, 助教 (00381369)
GOTOH Mitsukazu  福島県立医科大学, 医学部, 教授 (50162160)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords膵癌 / 樹状細胞 / OK-432 / 術前 / 腫瘍内局注
Research Abstract

On histological findings of DC group, colliquative necrosis with lymphocyte infiltration, which are uncommon findings of pancreatic cancer. CD83^+ cells were significantly accumulated in the regional lymph nodes of DC group. Two of 9 patients of DC group are currently alive over 5 years after surgery without any other adjuvant therapy. This is the first report of Preoperative EUS-guided intratumoral iDCs injection together with OK-432 for pancreatic cancer. Further investigations to confirm and to enhance antitumor response are warranted.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (8 results)

All 2010 2009 2008

All Presentation (8 results)

  • [Presentation] Preoperative Intratumoral Injectin of Immature Dendritic Cells with OK-432 for Resectable Pancreatic Cancer.2010

    • Author(s)
      見城明, 遠藤久仁, 齋藤拓朗, 後藤満一
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-24
    • Related Report
      2010 Final Research Report
  • [Presentation] Preoperative Intratumoral Injectin of Immature Dendritic Cells with OK-432 for Resectable Pancreatic Cancer2010

    • Author(s)
      見城明
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] Preoperative Intratumoral Injection of Immature DC with OK-432 for Resectable Pancreatic Cancer.2010

    • Author(s)
      見城明, 遠藤久仁, 斎藤拓朗, 後藤満一
    • Organizer
      International Congress of The 9^<th> Asian Clinical Oncology Society
    • Place of Presentation
      岐阜
    • Year and Date
      2010-08-25
    • Related Report
      2010 Final Research Report
  • [Presentation] Preoperative Intratumoral Injection of Immature DC with OK-432 for Resectable Pancreatic Cancer.2010

    • Author(s)
      見城明
    • Organizer
      International Congress of The 9^<th> Asian Clinical Oncology Society
    • Place of Presentation
      Gifu
    • Year and Date
      2010-08-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] 膵癌における術前樹状細胞局注療法の検討2010

    • Author(s)
      遠藤久仁, 見城明, 齋藤拓朗, 佐藤佳宏, 木村隆, 土屋貴男, 佐藤純, 後藤満一
    • Organizer
      第110回日本外科学会定期学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-04-08
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 膵癌切除症例に関する検討2009

    • Author(s)
      見城明, 齋藤拓朗, 佐藤佳宏, 木村隆, 佐藤純, 押部郁朗, 土屋貴男, 後藤満一
    • Organizer
      第21回日本肝胆膵外科学会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-06-11
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] 膵癌切除症例における長期生存に関する検討2009

    • Author(s)
      見城明, 齋藤拓朗, 佐藤佳宏, 木村隆, 佐藤純, 押部郁朗, 土屋貴男, 後藤満一
    • Organizer
      第109回日本外科学会定期学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2009-04-03
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] 術前樹状細胞腫瘍内局注を施行した膵癌症例の検討2008

    • Author(s)
      見城明, 斎藤拓朗, 佐藤佳宏, 土屋貴男, 木村隆, 穴澤貴行, 後藤満一
    • Organizer
      第39回日本膵臓学会
    • Place of Presentation
      横浜
    • Year and Date
      2008-07-30
    • Related Report
      2010 Final Research Report 2008 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi