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ヒト膵臓癌におけるシーエックスシーケモカインの検討(予後・背景因子・分化度)

Research Project

Project/Area Number 20591640
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Digestive surgery
Research InstitutionHyogo College of Medicine

Principal Investigator

SATAKE Makoto  Hyogo College of Medicine, 医学部, 助教 (70399153)

Co-Investigator(Kenkyū-buntansha) FUJIMOTO Jiro  兵庫医科大学, 医学部, 教授 (90199373)
KURODA Nobukazu  兵庫医科大学, 医学部, 講師 (20301658)
HIRANO Tadamichi  兵庫医科大学, 医学部, 講師 (90340968)
UYAMA Naoki  兵庫医科大学, 医学部, 助教 (70402873)
SUZUMURA Kazuhiro  兵庫医科大学, 医学部, 助教 (50434949)
Co-Investigator(Renkei-kenkyūsha) HOWARD A Reber  David Geffen school of Medicine at UCLA. Laboratory Director of Ronald S. Hirshberg Translation Pancreatic Cancer Research Laboratory, Professor of General Surgery
GO VLiang  Scientific Adivisory Board. David Geffen school of Medicine at UCLA. Laboratory Director of Ronald S. Hirshberg Translation Pancreatic Cancer Research Laboratory. Chief editor of journal Pancreas, Chair
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords膵臓癌 / ケモカイン / 血管新生 / レセプターシグナル / 増殖転移
Research Abstract

In human pancreatic cancer cell lines and tissue from patients with pancreatic cancer. Angiogenetic ELR+CXCL and its receptor CXCR2 were elevated. This over expression was correlated with the calcification of pancreatic cancer

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (22 results)

All 2010 2009 2008

All Presentation (18 results) Book (4 results)

  • [Presentation] The role of CXCLs and receptors CXCR2 and CXCR3 on human PaCa growth.2010

    • Author(s)
      Satake M., Kuroda N., Eibl G., Hirano T., Okada T., Hines O.J., Reber H.A., Go V.L., Uyama N., Suzumura K., Fujimoto J.
    • Organizer
      American pancreatic association meeting.
    • Place of Presentation
      Chicago, IL.U.S
    • Related Report
      2010 Final Research Report
  • [Presentation] ヒト膵臓癌発育におけるCOX-2, PGE2の役割2010

    • Author(s)
      佐竹真、黒田暢一、平野公通、岡田敏弘、Eibl G、Reber H.A., Go V.L、宇山直樹、鈴村和大、Hines O.J., 藤元治朗
    • Organizer
      日本膵臓病学会総会+IAP joint meeting.
    • Place of Presentation
      Fukuoka, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] COX-2 dependent expression of angiogenic CXC chemokines ligand in human pancreatic cancer cell line.2010

    • Author(s)
      Satake M., Kuroda N., Eibl G., Hirano T., Okada T., Reber H.A., Go V.L., Uyama N., Suzumura K., Hines O.J., Fujimoto J.
    • Organizer
      2010 AGA Meeting
    • Place of Presentation
      New Orleans. US
    • Related Report
      2010 Final Research Report
  • [Presentation] COX-2 dependent expression of angiogenic CXC chemokines ligand in human pancreatic cancer cell line.2010

    • Author(s)
      Satake Makoto
    • Organizer
      2010 AGA Meeting
    • Place of Presentation
      New Orleans US
    • Related Report
      2010 Annual Research Report
  • [Presentation] ヒト膵臓癌発育におけるCOX-2, PGE2の役割2010

    • Author(s)
      Satake Makoto
    • Organizer
      日本膵臓病学会総会+IAP joint meeting
    • Place of Presentation
      Fukuoka, Japan
    • Related Report
      2010 Annual Research Report
  • [Presentation] The role of CXCLs and receptors CXCR2 and CXCR3 on human PaCa growth2010

    • Author(s)
      Satake Makoto
    • Organizer
      American pancreatic association meeting.
    • Place of Presentation
      Chicago, IL U.S
    • Related Report
      2010 Annual Research Report
  • [Presentation] The role of CXCLs and receptors CXCR2 and CXCR3 on human PaCa growth.2009

    • Author(s)
      Satake M., Kuroda N., Eibl G., Hirano T., Okada T., Reber H.A., Go V.L., Uyama N., Suzumura K., Fujimoto J.
    • Organizer
      40^<th>.Joint Meeting of American pancreatic association and Japan Pnacreas Society.
    • Place of Presentation
      Hawaii. U.S
    • Related Report
      2010 Final Research Report
  • [Presentation] ヒト膵臓癌発育におけるCOX-2, PGE2の役割2009

    • Author(s)
      佐竹真、黒田暢一、平野公通、岡田敏弘、Eibl G、Reber H.A., Go V.L、宇山直樹、鈴村和大、Hines O.J., 藤元治朗
    • Organizer
      日本膵臓病学会総会
    • Place of Presentation
      東京、日本
    • Related Report
      2010 Final Research Report
  • [Presentation] Characterization of Pancreatic cancer cell by COX-2 dependent growth.2009

    • Author(s)
      Satake M., Kuroda N., Eibl G., Hirano T., Okada T., Reber H.A., Go V.L., Uyama N., Suzumura K., Fujimoto J.
    • Organizer
      AGA Meeting
    • Place of Presentation
      Chicago, IL.U.S.
    • Related Report
      2010 Final Research Report
  • [Presentation] Characterization of Pancreatic cancer cell by COX-2 dependent growth2009

    • Author(s)
      Satake Makoto
    • Organizer
      AGA Meeting
    • Place of Presentation
      Chicago.US
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒト膵臓癌発育におけるCOX-2,PGE2の役割2009

    • Author(s)
      佐竹真
    • Organizer
      日本膵臓病学会総会
    • Place of Presentation
      東京 日本
    • Related Report
      2009 Annual Research Report
  • [Presentation] The role of CXCLs and receptors CXCR2 and CXCR3 on human PaCa growth2009

    • Author(s)
      Satake Makoto
    • Organizer
      American pancreatic association meeting.
    • Place of Presentation
      Hawaii U.S
    • Related Report
      2009 Annual Research Report
  • [Presentation] The role of SCF/KIT system in pancreatic transdifferentiation.2008

    • Author(s)
      Satake M., Kuroda N., Eibl G., Hirano T., Okada T., Reber H.A., Go V.L., Uyama N., Suzumura K., Fujimoto J., Tsujimura T.
    • Organizer
      American pancreatic association meeting.
    • Place of Presentation
      Chicago, IL.U.S
    • Related Report
      2010 Final Research Report
  • [Presentation] 膵幹細胞からの膵細胞再生についての検討,Tyrosine kinase receptorの役割2008

    • Author(s)
      佐竹真、黒田暢一、平野公通、岡田敏弘、Eibl G、Reber H.A., Go V.L、宇山直樹、鈴村和大、藤元治朗, 辻村亨
    • Organizer
      日本消化器外科学会
    • Place of Presentation
      札幌 日本
    • Related Report
      2010 Final Research Report
  • [Presentation] Pancreatic transdifferentiation induced from stem cell.2008

    • Author(s)
      Satake M., Kuroda N., Eibl G., Hirano T., Okada T., Reber H.A., Go V.L., Uyama N., Suzumura K., Fujimoto J., Tsujimura T.
    • Organizer
      AGA Meeting
    • Place of Presentation
      San Diego. CA.US
    • Related Report
      2010 Final Research Report
  • [Presentation] Pancreatic transdifferentiation induced from stem cell2008

    • Author(s)
      Satake Makoto
    • Organizer
      AGA Meeting
    • Place of Presentation
      Los Angeles. US
    • Related Report
      2008 Annual Research Report
  • [Presentation] 膵幹細胞からの膵細胞再生についての検討, Tyrosine kinase receptorの役割2008

    • Author(s)
      佐竹真
    • Organizer
      日本消化器外科学会
    • Place of Presentation
      札幌日本
    • Related Report
      2008 Annual Research Report
  • [Presentation] The role of SCF/KIT system in pancreatic transdifferentiation2008

    • Author(s)
      Satake Makoto
    • Organizer
      American pancreatic association meeting.
    • Place of Presentation
      Chicago U. S
    • Related Report
      2008 Annual Research Report
  • [Book] 胆と膵(膵癌におけるプロスタグランディン 膵基礎研究の新しい潮流 vol.31.No6)2010

    • Author(s)
      佐竹真、黒田暢一、藤元治朗
    • Publisher
      医学図書出版
    • Related Report
      2010 Final Research Report
  • [Book] 胆と膵vol.31.No6膵基礎研究の新しい潮流2010

    • Author(s)
      佐竹真, 藤元治朗
    • Publisher
      医学図書出版
    • Related Report
      2010 Annual Research Report
  • [Book] 腫瘍マーカーハンドブック(改訂版)2010

    • Author(s)
      佐竹真, 藤元治朗
    • Total Pages
      295
    • Publisher
      医薬ジャーナル者
    • Related Report
      2009 Annual Research Report
  • [Book] Span-1,腫瘍マーカーハンドブック(石井勝編集)2009

    • Author(s)
      佐竹克介,佐竹真,藤元治朗
    • Publisher
      医薬ジャーナル
    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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