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The absorbable process of bioengineered graft assessed by in vivo imaging

Research Project

Project/Area Number 20591644
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Thoracic surgery
Research InstitutionOsaka University

Principal Investigator

KOTANI Junichi  Osaka University, 心臓血管内科, 医長 (10448029)

Co-Investigator(Kenkyū-buntansha) SAITO Mitsuhiro  大阪大学, 医学部付属病院, 特任助教 (20448038)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords血管内イメージング / 循環器 / 自己組織化グラフト / 血管内イメージング法 / 内視鏡評価 / 新生内膜 / 人工血管 / 内皮化
Research Abstract

The potent mechanism of bioabsorbable graft was considered two ways : contact between blood cells and luminal surface, and contact between adventitia and neighbor tissue. These were assessed by color, smoothing of the surface, and neovascularization outside the graft. The findings were observed by intravascular ultrasound, optical coherence tomography and angioscopy ; those are used in clinical. Serial observation using imaging modality in vivo may become a new methodology instead of patho-histological assessment after scarified animal.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (6 results)

All 2011 2010 Other

All Journal Article (1 results) Presentation (2 results) Book (2 results) Remarks (1 results)

  • [Journal Article] Assessment of intracoronary stents by coronary angioscopy2010

    • Author(s)
      Jun-ichi Kotani
    • Journal Title

      Cardiology International

      Pages: 113-116

    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Update on Coronary Angioscopy(血管内視鏡の最先端)2010

    • Author(s)
      Jun-ichi Kotani
    • Organizer
      The3^<rd> left main and coronary bifurcation summit
    • Place of Presentation
      Nanjin, China(中国・南京)
    • Year and Date
      2010-11-26
    • Related Report
      2010 Final Research Report
  • [Presentation] Update on Coronary Angioscopy (血管内視鏡の最先端)2010

    • Author(s)
      Jun-ichi Kotani
    • Organizer
      The3^<rd> left main and coronary bifurcation summit
    • Place of Presentation
      Nanjin China(中国・南京)
    • Year and Date
      2010-11-26
    • Related Report
      2010 Annual Research Report
  • [Book] 血管内視鏡最新診療ガイド2011

    • Author(s)
      小谷順一
    • Total Pages
      189
    • Publisher
      Medical View社(東京)
    • Related Report
      2010 Final Research Report
  • [Book] 血管内視鏡最新診療ガイド2011

    • Author(s)
      小谷順一
    • Total Pages
      189
    • Publisher
      Medical View 社(東京)
    • Related Report
      2010 Annual Research Report
  • [Remarks] ホームページ等なし

    • Related Report
      2010 Final Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

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