Efficacy of surgical ventricular restoration based on the evaluation of the myocardial viability with delayed-enhanced magnetic resonance imaging

• Project/Area Number: 20591653
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Thoracic surgery
• Research Institution: Kyoto Prefectural University of Medicine
• Principal Investigator: OKAWA Kazunari Kyoto Prefectural University of Medicine, 医学研究科, 助教 (80405290)
• Co-Investigator(Kenkyū-buntansha): YAKU Hitoshi 京都府立医科大学, 医学研究科, 教授 (50295648)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 虚血性心筋 / 症左室形成 / 術遅延造影MRI / 虚血性心筋症 / 左室形成術 / 遅延造影MRI

Research Abstract

Assessment of myocardial viability is important when applying surgical ventricular restoration (SVR) for ischemic cardiomyopathy. Delayed-enhanced magnetic resonanceimaging (DE-MRI) can detect necrotic areas with high spatial resolution. We assessedwhether our surgical strategy incorporating DE-MRI is effective. As a result, DE-MRI canclearly delineate scar areas within the whole ventricle and therefore can play animportant role in determining whether and which areas should be excluded by SVR. Thisstrategy based on the DE-MRI assessments can assist in providing excellent clinical outcomes in ischemic cardiomyopathy.

Research Products

• [Journal Article] Endocardial linear infarct exclusion technique(ELIET)を用いた左室形成術 : Dor 手術との比較 (2010)
  • Author(s): 土井潔、夜久均
  • Journal Title: 日本冠疾患学会雑誌 16 Pages: 197-201
  • NAID: 10027659988
• [Journal Article] 虚血性心筋症に対して左室形成術は有効か?-STICH trial をめぐる諸問題- (2010)
  • Author(s): 夜久均
  • Journal Title: 京都府立医科大学雑誌 119(4) Pages: 237-245
• [Presentation] 遅延造影MRIによる心筋viability評価に基づいた虚血性心筋症の治療成績 (2010)
  • Author(s): 大川和成、土井潔、小川貢、山南将志、土肥正浩、木谷公紀、眞鍋嘉一郎、夜久均
  • Organizer: 第24回日本冠疾患学会学術集会
  • Place of Presentation: 東京ステーションコンファレンス
  • Year and Date: 2010-12-10
• [Presentation] 遅延造影MRIによる心筋viability評価に基づいた虚血性心筋症の治療成績 (2010)
  • Author(s): 大川和成、土井潔、小川貢、山南将志、土肥正浩、木谷公紀、臼井亮介、眞鍋嘉一郎、夜久均
  • Organizer: 第63回日本胸部外科学会定期学術集会
  • Place of Presentation: 大阪国際会議場
  • Year and Date: 2010-10-26
• [Presentation] 左室形成術(ELIET)後の中期成績:残存心筋viabilityから見た検討 (2010)
  • Author(s): 土井潔、大川和成、小川貢、山南将志、土肥正浩、木谷公紀、夜久均
  • Organizer: 第63回日本胸部外科学会定期学術集会
  • Place of Presentation: 大阪国際会議場
  • Year and Date: 2010-10-26
• [Presentation] A New Technique for Surgical Ventricular Restoration :Was the STICH Trial Justified? (2010)
  • Author(s): Yaku H, Doi K, Okawa K, Dohi M, Kitani K, Ogawa M
  • Organizer: The 6^<th> International joint Meeting
  • Place of Presentation: Tianjin, China
  • Year and Date: 2010-06-26
• [Presentation] Assessment of Myocardial Viability by Late-Enhancement Magnetic Resonance Imaging : Usefulness in Determining Indication and the Area of Surgical Ventricular Restoration (2010)
  • Author(s): Yaku H, Doi K, Yamazaki S, Okawa K, Dohi M, Sasaki Y, Ogawa M
  • Organizer: The International Society for Minimally Invasive Cardiothoracic Surgery 2010 Annual Meeting
  • Place of Presentation: Berlin, Germany
  • Year and Date: 2010-06-16
• [Presentation] 遅延造影MRI による心筋viability 評価に基づいた虚血性心筋症の治療成績.外科シンポジウム2;本邦におけるSVR の治療成績vs STiCH trial (2010)
  • Author(s): 大川和成、土井潔、小川貢、山南将志、土肥正浩、木谷公紀、眞鍋嘉一郎、夜久均
  • Organizer: 第24回日本冠疾患学会学術集会
  • Place of Presentation: 東京
• [Presentation] 左室形成術(ELIET)後の中期成績:残存心筋viability から見た検討.シンポジウム6;STICH Trial から、われわれはどこに向かうのか (2010)
  • Author(s): 土井潔、大川和成、小川貢、山南将志、土肥正浩、木谷公紀、夜久均
  • Organizer: 第63回見本胸部外科学会定期学術集会
  • Place of Presentation: 大阪
• [Presentation] 遅延造影MRI による心筋viability 評価に基づいた虚血性心筋症の治療成績 (2010)
  • Author(s): 大川和成、土井潔、小川貢、山南将志、土肥正浩、木谷公紀、臼井亮介、眞鍋嘉一郎、夜久均
  • Organizer: 第63回日本胸部外科学会定期学術集会
  • Place of Presentation: 大阪
• [Presentation] A New Technique for Surgical Ventricular Restoration: Was the STICH Trial Justified (2010)
  • Author(s): 夜久均, 土井潔, 大川和成, 土肥正浩, 木谷公紀, 小川貢
  • Organizer: The 6^<th> International Joint Meeting
  • Place of Presentation: Tianjin, China
• [Presentation] Assessment of Myocardial Viability by Late-Enhancement Magnetic Resonance Imaging: Usefulness in Determining Indication and the Area of Surgical Ventricular Restoration. (2010)
  • Author(s): Yaku H, Doi K, Yamazaki S, Okawa K, Dohi M, Sasaki Y, Ogawa M
  • Organizer: The International Society for Minimally Invasive Cardiothoracic Surgery (ISMICS) 2010 Annual Meeting
  • Place of Presentation: Berlin, Germany
• [Presentation] 左室形成術の適応と方法Endocardial linear Infarct ExclusionTechnique による左室形成術 (2009)
  • Author(s): 土井潔、夜久均、大川和成、山崎祥子、土肥正浩、佐々木裕二、浅田聡、森本和樹
  • Organizer: 第23回日本冠疾患学会
  • Place of Presentation: 大阪
• [Presentation] Surgical Strategy and Outcomes for Ischemic Cardiomyopathy Based on the Assessment of Myocardial Viability by Late-Enhancement Magnetic Resonance Imaging. (2009)
  • Author(s): Ogawa M, Doi K, Okawa K, Dohi M, Kitani K, Kawajiri H, Yaku H
  • Organizer: The 17^<th> Annual Meeting of Asian Society for Cardiovascular and Thoracic Surgery
  • Place of Presentation: Taipei, Taiwan
• [Presentation] New Surgical Method for Ventricular Restoration for the Lateral Wall ; Endocardial linear Infarct Exclusion Technique (ELIET) (2009)
  • Author(s): 夜久均
  • Organizer: The 17^<th> Annual Meeting of Asian Society for Cardiovascular and Thoracic Surgery
  • Place of Presentation: Taipei, Taiwan
• [Presentation] 遅延造影MRIによる心筋viability評価に基づいた虚血性心筋症にたする左室形成術と遠隔成績 (2008)
  • Author(s): 小川 貢
  • Organizer: 第13回日本冠動脈外科学会
  • Place of Presentation: 東京
  • Year and Date: 2008-07-16
• [Presentation] Endocardial linear Infarct Exclusion Technique : A new technique for ventricular restoration. (2008)
  • Author(s): Doi K, Yaku H, Kitani K, Dohi M, Okawa K, Kawajiri H
  • Organizer: ISMICS2008 Winter Workshop
  • Place of Presentation: Okinawa, Japan
• [Presentation] Endocardial Linear Infarct ExclusionTechnique を用いた左室形成術 (2008)
  • Author(s): 土井潔、夜久均、大川和成、山崎祥子、土肥正浩、木谷公紀、川尻英長
  • Organizer: 第61回日本胸部外科学会定期学術集会
  • Place of Presentation: 福岡
• [Presentation] Endocardial Linear Infarct Exclusion Technique For Lateral wall : A new technique for ventricular restoration. (2008)
  • Author(s): 夜久均
  • Organizer: 22^<nd> EACTS
  • Place of Presentation: Lisbon Portugal
• [Presentation] 虚血性心筋症に対する新しい左室形成術-Endocardial Linear Infarct Exclusion Technique- (2008)
  • Author(s): 夜久均、土井潔、大川和成、山南将志、木谷公紀、小川貢
  • Organizer: 第13回日本冠動脈外科学会
  • Place of Presentation: 東京
• [Presentation] 遅延造影MRI による心筋viability 評価に基づいた虚血性心筋症に対する左室形成術と遠隔成績 (2008)
  • Author(s): 小川貢、土井潔、山田義明、大川和成、山南将志、木谷公紀、夜久均
  • Organizer: 第13回日本冠動脈外科学会
  • Place of Presentation: 東京
• [Book] II冠動脈外科/虚血性心筋症の手術私の￠左室形成術￡.図説成人心臓血管外科手術を究めるII (2009)
  • Author(s): 夜久均、土井潔
  • Publisher: メジカルビュー社
• [Book] 2.狭心症に対する冠動脈バイパス術2)心筋バイアビリティー評価.心臓血管外科テクニック (2009)
  • Author(s): 小川貢、土井潔、夜久均
  • Publisher: メディカ出版
• [Book] 心臓血管外科テクニックIII冠動脈・心筋疾患編2.2)心筋バイアビリティー評価 (2009)
  • Author(s): 小川貢、夜久均
  • Total Pages: 232
  • Publisher: (株)メディカ出版