Mechanisms of stroke progression by periodontal bacteria
| Project/Area Number |
20591683
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Hamamatsu University School of Medicine |
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Principal Investigator |
HOKAMURA Kazuya Hamamatsu University School of Medicine, 医学部・薬理学, 特任助教 (90436965)
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| Co-Investigator(Kenkyū-buntansha) |
UMEMURA Kazuo 浜松医科大学, 医学部・薬理学, 教授 (40232912)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 脳梗塞 / 脳出血 / 口腔内細菌 / う蝕 / 歯周病 / 全身疾患 / 歯周病菌 / う蝕菌 |
|---|
| Research Abstract |
It was demonstrated with oral bacteria to mice cerebral hemorrhage model, and 24 hours later, brain tissue harvested 2 mm thickness and analyzed brain hemorrhage area. Administered with general oral bacteria was no effect to the cerebral hemorrhage. However, with collagen binding protein was enhanced cerebral hemorrhage during a stroke.
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Report
(4 results)
Research Products
(22 results)
