Translational Research for Clinical Application of Autologous Bone Marrow Stromal Cell Transplantation for CNS disorders
| Project/Area Number |
20591701
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Hokkaido University |
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Principal Investigator |
HIDA Kazutoshi Hokkaido University, 大学院・医学研究科, 准教授 (10238305)
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| Co-Investigator(Kenkyū-buntansha) |
KURODA Satoshi 北海道大学, 病院, 講師 (10301904)
SHICHINOHE Hideo 北海道大学, 病院, 助教 (80374479)
IWASAKI Yoshinobu 北海道大学, 大学院・医学研究科, 名誉教授 (00113522)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 神経再生 / 骨髄間質細胞 / 脊髄損傷 / 脳損傷 / 脳梗塞 / 再生医療 / Bane marrow stromal cell / Transplantation / Cerebral infarction / Spinal cord injury / Diffuse axonal injury / Differentiation / Regenerative medicine / Functional restoration / Bone marrow stromal cell / Spinal cord iniury / Diffuse axonal iniury |
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| Research Abstract |
For these 3 years, we have run many experiments and explored many new knowledge on autologous bone marrow stromal cell transplantation for central nervous system disorders. We have reported the novel aspects of their biological features and the utility of bioimaging technology such as MRI and optical imaging. This report shows the brief summary of these knowledge.
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Report
(4 results)
Research Products
(123 results)
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[Journal Article] Bone marrow stromal cells differentiate into neurons and promote axon elongation in spinal cord slice cultures: Their role in cell transplantation therapy for spinal cord injury.2008
Author(s)
Shichinohe H, Kuroda S, Tsuji S, Yamaguchi S, Yano S, Lee JB, Kobayashi H, Hokari M, Hida K, Kikuchi S, Iwasaki Y
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Journal Title
Neurorehabil Neural Repair 22
Pages: 447-457
Related Report
Peer Reviewed
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