| Project/Area Number |
20591728
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Osaka Medical College |
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Principal Investigator |
KAWABATA Shinji Osaka Medical College, 医学部, 助教 (20340549)
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| Co-Investigator(Kenkyū-buntansha) |
NONOGUCHI Naosuke 大阪医科大学, 医学部, 非常勤講師 (70388263)
YAMADA Yoshitaka 大阪医科大学, 医学部, 非常勤講師 (00368101)
IKEDA Naokado 大阪医科大学, 医学部, 助教 (50434775)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 脳腫瘍 / 粒子線治療 / ポルフィリン / 中性子捕捉療法 / 神経膠腫 / 光線力学療法 / Convection enhanced delivery / 血液脳関門 |
|---|
| Research Abstract |
In the boronated porphyrin, we give it as a PDD use at initial surgery in preoperation and perform PDT as intraoperative irradiation and would be able to measure the boron contents of the tumor in the individual patient. An advantage to be able to use this actual value in a judgment of indication, dose assessment was, thereby, thought about when we performed BNCT following surgery. Because the boronated porphyrin is full of visibility and shows high accumulation for the tumor, this compound can expect effect of treatment in the both PDT and BNCT.
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