Establishment of anti-angiogenic therapy for soft tissue sarcomsas
| Project/Area Number |
20591762
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Sapporo Medical University |
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Principal Investigator |
KAYA Mitsunori Sapporo Medical University, 医学部, 講師 (10398315)
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| Co-Investigator(Kenkyū-buntansha) |
WADA Takuro 札幌医科大学, 道民医療推進学講座, 特任教授 (00244369)
YAMASHITA Toshihiko 札幌医科大学, 医学部, 教授 (70244366)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 軟部肉腫 / 遠隔転移 / 局所浸潤 / 血管新生 / 局所侵潤 |
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| Research Abstract |
To establish the anti-angiogenic therapy for soft tissue sarcomas, the risk factors of the local recurrence of myxofibrosarcoma were retrospectively analyzed. Inadequate surgical margins and bone and/or joint attachment were associated with an increased recurrence rate. Further evaluation of the role of angiogenesis to invasiveness of myxofibrosarcoma will be necessary for the establishment of anti-angiogenic therapy for soft tissue sarcoma.
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Report
(4 results)
Research Products
(17 results)
