Study on a mechanism of emergence from general anesthesia-apply of the ascending arousal system for smooth recovery from general anesthesia
| Project/Area Number |
20591797
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Hirosaki University |
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Principal Investigator |
KUSHIKATA Tetsuya Hirosaki University, 医学部・附属病院, 講師 (80250603)
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| Co-Investigator(Kenkyū-buntansha) |
HIROTA Kazuyoshi 弘前大学, 大学院・医学研究科, 教授 (20238413)
YOSHIDA Hitoshi 弘前大学, 大学院・医学研究科, 講師 (00374843)
KUDO Mihoko 弘前大学, 大学院・医学研究科, 助教 (30003411)
工藤 剛 弘前大学, 大学院・医学研究科, 助教 (70003407)
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| Co-Investigator(Renkei-kenkyūsha) |
KUDO Mihoko 弘前大学, 大学院・医学研究科, 助教 (30003411)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 麻酔学 / 麻酔の質 / 覚醒 / 麻酔科学 |
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| Research Abstract |
We Studied effect of Neuropeptide S (NPS) on NA, Ach, HA, and glutamate release from male adult SD rat cerebral cortex. NPS had no effect on these substances release. We also examined if NPS or Orexin had any effect on thiopental or ketamine anesthesia time, and ketamine-induced sleep disturbance. NPS decreased these anesthesia times. NPS and OX decreased the sleep disturbance.
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Report
(4 results)
Research Products
(14 results)
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[Journal Article] Urotensin II evokes neurotransmitter release from rat cerebrocortical slices2008
Author(s)
Ono T, Kawaguchi Y, Kudo M, Kushikata T, Hashiba E,Yoshida H, Kudo T, Furukawa K, Douglas SA, Guerrini R, Calo' G, Hirota K
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Journal Title
Neurosci Lett 440巻
Pages: 275-279
Related Report
Peer Reviewed
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[Journal Article] Urotensin II evokes neurotransmitter release from rat cerebrocortical slices2008
Author(s)
Ono T, Kawaguchi Y, Kudo M, Kushikata T, Hashiba E, Yoshida H, Kudo T, Furukawa K, Douglas SA, Guerrini R, Calo G, Hirota K
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Journal Title
Neurosci Lett 440(3)
Pages: 275-279
Related Report
Peer Reviewed
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