The effect of the single nucleotide polymorphism on the changing of hemodynamics during general anesthesia
| Project/Area Number |
20591815
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Wakayama Medical University |
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Principal Investigator |
KIMOTO Yoshiki 和歌山県立医科大学, 医学部, 講師 (20316110)
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| Co-Investigator(Kenkyū-buntansha) |
畑埜 義雄 和歌山県立医科大学, 医学部, 教授 (70115913)
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| Project Period (FY) |
2008 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 遺伝子多型 / 血圧 / 麻酔薬 / 血圧変動 / Rho / 麻酔 / 予測 / Rho kinase / Rhoキナーゼ |
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| Research Abstract |
It is well known that single nucleotide polymorphism(SNP) in rock gene "one of the causes genes of hypertension" induced the significant increase in blood pressure. We studied the frequency of rock2 gene SNP(rs9808232), the effects of this gene on the blood pressure and the hemodynamic effects of this gene during anesthetic induction in Japanese population.
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Report
(6 results)
Research Products
(17 results)
