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Study on milk secretion of fentanyl was administered during The perioperative period of maternity.

Research Project

Project/Area Number 20591837
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Anesthesiology/Resuscitation studies
Research InstitutionKagoshima University

Principal Investigator

NAGATA Etsuro  Kagoshima University, 医学部・歯学部附属病院, 講師 (50437977)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2010: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords薬理学 / 発生・分化 / 細胞・組織 / フェンタニル / 持続硬膜外投与 / 乳汁中分泌 / LC-MS
Research Abstract

For pregnant women 20μg/hour fentanyl was administered for epidural analgesia after Caesarean section. Fentanyl concentrations in milk in one hour after the start was 0.08ng/ml. And 4, 6, 12, 24 hours later the concentration was below the detection limit. Concentration in milk secretion is very low, 20μg/hour dose epidural fentanyl concentration and that is safe to do neonatal nursing.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report

Research Products

(14 results)

All 2010 2009 2008

All Journal Article (4 results) (of which Peer Reviewed: 2 results) Presentation (10 results)

  • [Journal Article] これだけは知っておきたい!産科麻酔Q&A 帝王切開の麻酔 各論 多胎2010

    • Author(s)
      永田悦朗、上村裕一
    • Journal Title

      麻酔科学レクチャー 2(2)

      Pages: 279-282

    • Related Report
      2010 Final Research Report
  • [Journal Article] これだけは知っておきたい!産科麻酔Q&A帝王切開の麻酔 各論 多胎2010

    • Author(s)
      永田悦朗、上村裕一
    • Journal Title

      麻酔科学レクチャー

      Volume: 2(2) Pages: 279-282

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 胸腔鏡下手術直後にBare Metal Stent内の遅発性血栓症を生じた一症例2009

    • Author(s)
      二木貴弘, 他
    • Journal Title

      循環制御

      Volume: 30 Pages: 100-104

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Systematic evaluation of nitric oxide, tetrahydrobiopterin, and anandamide levels in a porcine model of endotoxemia2008

    • Author(s)
      Tetsuaki Hashiguchi, et al
    • Journal Title

      Journal of Anesthesia 22

      Pages: 213-220

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 手術を必要としたモルヒネ投与患者にフェンタニル1剤投与で周術期鎮静を行った1例2010

    • Author(s)
      久米村正輝、永田悦朗
    • Organizer
      九州麻酔科学会第48回大会
    • Place of Presentation
      福岡市
    • Year and Date
      2010-09-25
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] TIVA Trainerを用いた術後IVPCA管理2010

    • Author(s)
      今元那津美, 他
    • Organizer
      日本麻酔科学会第57回学術集会
    • Place of Presentation
      福岡市
    • Year and Date
      2010-06-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] 三尖弁閉鎖不全症合併時のNICOモニターの有用性2010

    • Author(s)
      今給黎南香, 他
    • Organizer
      日本麻酔科学会第57回学術集会
    • Place of Presentation
      福岡市
    • Year and Date
      2010-06-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] JM-1232のヒト血管平滑筋への作用についての検討2009

    • Author(s)
      森山孝宏, 他
    • Organizer
      (社)日本麻酔科学会第56回学術集会
    • Place of Presentation
      兵庫県神戸市
    • Year and Date
      2009-08-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] 三尖弁閉鎖不全症合併時の心拍出量測定法の検討2009

    • Author(s)
      今給黎南香, 他
    • Organizer
      (社)日本麻酔科学会第56回学術集会
    • Place of Presentation
      兵庫県神戸市
    • Year and Date
      2009-08-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] コハク酸シベンゾリンの投与によって僧帽弁形成術後のSAMが改善した1症例2008

    • Author(s)
      山田佳奈, 他
    • Organizer
      日本臨床麻酔学会第28回大会
    • Place of Presentation
      京都市
    • Year and Date
      2008-11-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] 体表マッピング機能を有する神経刺激装置 Stimuplex(R)HNS12の使用経験2008

    • Author(s)
      山口智美, 他
    • Organizer
      九州麻酔科学会第46回大会
    • Place of Presentation
      福岡市
    • Year and Date
      2008-09-27
    • Related Report
      2008 Annual Research Report
  • [Presentation] 僧帽弁形成術後体外循環離脱時に発症したSAMに対する治療, 予後の検討2008

    • Author(s)
      今給黎南香, 他
    • Organizer
      (社)日本麻酔科学会第55回学術集会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2008-06-14
    • Related Report
      2008 Annual Research Report
  • [Presentation] カテコラルミン心筋症を合併した慢性維持透析患者における褐色細胞腫摘出術の麻酔経験2008

    • Author(s)
      山田佳奈, 他
    • Organizer
      (社)日本麻酔科学会第55回学術集会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2008-06-13
    • Related Report
      2008 Annual Research Report
  • [Presentation] 胸腔鏡下縦隔リンパ節生検直後に bare metal stent 内に遅発性血栓症を生じた一例2008

    • Author(s)
      二木貴弘, 他
    • Organizer
      第29回日本循環制御医学会総会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2008-05-10
    • Related Report
      2008 Annual Research Report

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Published: 2008-03-31   Modified: 2016-04-21  

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