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Development of novel gene therapy for hormone refractory prostate cancer

Research Project

Project/Area Number 20591868
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Urology
Research InstitutionJikei University School of Medicine

Principal Investigator

KIYOTA Hiroshi  Jikei University School of Medicine, 医学部, 准教授 (30153240)

Co-Investigator(Kenkyū-buntansha) KIMURA Takahiro  東京慈恵会医科大学, 医学部, 助教 (00307430)
MIKI Jun  東京慈恵会医科大学, 医学部, 助教 (00328361)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords癌 / 泌尿器科 / 前立腺癌 / 遺伝子治療
Research Abstract

The aim of this study is to develop the new gene therapy using lentiviral vector with prostate-specific promoter that induces therapeutic gene to prostate cancer specifically. Lentiviral vectors with prostate-specific promoters were constructed and the efficiency was observed in vitro and in vivo models.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

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