| Project/Area Number |
20591913
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
|
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| Research Institution | Osaka University |
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Principal Investigator |
TANIGUCHI Yukiko Osaka University, 医学系研究科, 助教 (60423175)
|
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| Co-Investigator(Kenkyū-buntansha) |
TOMIMATSU Takuji 大阪大学, 大学院・医学系研究科, 助教 (30346209)
KANAGAWA Takeshi 大阪大学, 大学院・医学系研究科, 助教 (40346218)
MIMURA Kazuya 大阪大学, 医学系研究科, 助教 (50437422)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
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| Keywords | 低酸素性虚血性脳症 / CRP / 未熟ラット / 低酸素性虚血性脳障害 / 新生児 |
|---|
| Research Abstract |
In utero exposure to infection or inflammation is a strong and independent predictor of cerebral palsy. Using a rat model of neonatal hypoxic-ischemic encephalopathy, we investigated the hypothesis that C-reactive protein (CRP), which is not specific for infection, aggrabates vulnerability of the immature brain to HI.
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