| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
|
|---|
| Research Abstract |
We found that infected HPV caused up-regulation of the insulin-like growth factor receptor in cervical cancer cell lines. By using this phenomenon, we evaluated expression levels and its localization of IGF-IR in human cervical cancer and its precursor lesions by immunohistochemistry. We could distinguish status of HPV infection by the localization of IGF-IR overexpression. Then we tried to utilize this technique in liquid based cytology specimens. However, we could not distinguish HPV infection status from cytology specimens.
|
