| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Research Abstract |
This small proof of principle study demonstrates that there are profiles in the serum of Japanese ovarian cancer patients that can classify the presence of cancer. The information is similar to that in USA ovarian cancer sera since N-dimensional clusters built on USA sera spectra created cluster maps predictive of the Japanese samples. Performance of the model was better than any of the existing single biomarker assays although truly useful models await a much larger sample size and the use of independent validation sample sets to demonstrate the robustness of the models. These results encourage us to initiate a large scale, multi-site collection of serum from Japanese ovarian cancer samples patients, for the development of a Japanese ovarian cancer serum profile assay.
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