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Therapeutic strategy for prevention of the recurrent middle ear cholesteatoma

Research Project

Project/Area Number 20591974
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Otorhinolaryngology
Research InstitutionNiigata University

Principal Investigator

TAKAHASHI Sugata  Niigata University, 医歯学系, 教授 (10154824)

Co-Investigator(Kenkyū-buntansha) YAMAMOTO Yutaka  新潟大学, 医歯学総合病院, 講師 (10313545)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords中耳真珠腫 / 治療 / 乳突削開術 / 乳突腔充填術 / 遺残性真珠腫 / 乳突腔削開術
Research Abstract

Efficacy of the mastoid obliteration for the patients with middle ear cholesteatoma has been well recognized, however, the long-term stability after this surgical procedure and the risk of residual cholesteatoma are still in discussion. The aims of this study were to demonstrate postoperative stability of the reconstructed posterior canal wall made with bone pate and to evaluate the pathogenesis of residual cholesteatoma in the obliterated mastoid cavity. We successfully established the animal models of mastoid obliteration and residual cholesteatoma.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (13 results)

All 2010 2009 2008

All Journal Article (3 results) Presentation (10 results)

  • [Journal Article] 症例に則した鼓室形成術-右慢性中耳炎、蝸牛瘻孔を伴う左真珠腫性中耳炎-.2009

    • Author(s)
      高橋姿
    • Journal Title

      Otology Japan 19

      Pages: 9-11

    • NAID

      10025822248

    • Related Report
      2010 Final Research Report
  • [Journal Article] 症例に則した鼓室形成術-右慢性中耳炎、蝸牛瘻孔を伴う左真珠腫性中耳炎2009

    • Author(s)
      高橋姿
    • Journal Title

      Otology Japan 19

      Pages: 9-11

    • NAID

      10025822248

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 耳科手術-危険部位と合併症-その対策と治療.2008

    • Author(s)
      高橋姿
    • Journal Title

      日耳鼻 111

      Pages: 70-73

    • NAID

      10024371096

    • Related Report
      2010 Final Research Report
  • [Presentation] 真珠腫手術と副損傷の回避2010

    • Author(s)
      高橋姿
    • Organizer
      東京大学冬期検討会講演会
    • Place of Presentation
      東京都
    • Year and Date
      2010-12-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] 中耳真珠腫の治療戦略.2010

    • Author(s)
      高橋姿
    • Organizer
      日本耳鼻咽喉科学会群馬県地方部会
    • Place of Presentation
      前橋市
    • Year and Date
      2010-12-12
    • Related Report
      2010 Final Research Report
  • [Presentation] 中耳真珠腫の治療戦略2010

    • Author(s)
      高橋姿
    • Organizer
      日本耳鼻咽喉科学会群馬県地方部会
    • Place of Presentation
      前橋市
    • Year and Date
      2010-12-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] Cholesteatoma Surgery with Mastoid Obliteration and Ossiculoplasty Using Autograft Cortical Bone.2009

    • Author(s)
      高橋姿
    • Organizer
      27th Politzer Society Meeting
    • Place of Presentation
      London, UK
    • Year and Date
      2009-09-04
    • Related Report
      2010 Final Research Report
  • [Presentation] 乳突充填術後の遺残性真珠腫の検討2009

    • Author(s)
      高橋姿
    • Organizer
      第110回日本耳鼻喉科学会総会
    • Place of Presentation
      ザ・プリンスパークタワー東京
    • Related Report
      2009 Annual Research Report
  • [Presentation] Cholesteatoma surgery with mastoid obliteration and ossiculoplasty using autograft cortical bone2009

    • Author(s)
      高橋姿
    • Organizer
      27th Politzer Society Meeting
    • Place of Presentation
      イギリス ロンドン
    • Related Report
      2009 Annual Research Report
  • [Presentation] パネルディスカッション:症例に則した鼓室形成術.2008

    • Author(s)
      高橋姿
    • Organizer
      第18回日本耳科学会
    • Place of Presentation
      神戸市
    • Year and Date
      2008-10-18
    • Related Report
      2010 Final Research Report
  • [Presentation] パネルディスカッション「症例に則した鼓室形成術」2008

    • Author(s)
      高橋姿
    • Organizer
      第18回日本耳科学会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2008-10-18
    • Related Report
      2008 Annual Research Report
  • [Presentation] Round table : Long term results of mastoid obliteration in cholesteatoma cases.2008

    • Author(s)
      高橋姿
    • Organizer
      8th International Conference on Cholesteatoma & Ear Surgery
    • Place of Presentation
      Antalya, Turkey
    • Year and Date
      2008-06-16
    • Related Report
      2010 Final Research Report
  • [Presentation] cholesteatoma surgery- current trends in Japan.2008

    • Author(s)
      高橋姿
    • Organizer
      8th International Conference on Cholesteatoma & Ear Surgery
    • Place of Presentation
      Antalya, Turkey
    • Year and Date
      2008-06-16
    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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