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Ocular vestibular evoked myogenic potentials in monkeys

Research Project

Project/Area Number 20591975
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Otorhinolaryngology
Research InstitutionUniversity of Toyama

Principal Investigator

SHOJAKU Hideo  University of Toyama, 大学院・医学薬学研究部(医学), 准教授 (60187507)

Co-Investigator(Kenkyū-buntansha) HORI Etsuro  富山大学, 大学院・医学薬学研究部(医学), 准教授 (90313600)
坪田 雅仁  富山大学, 大学院・医学薬学研究部(医学) 耳鼻咽喉科頭頸部外科学, 研究協力員 (90436791)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywordsサル / 強大音 / 誘発筋電位 / 外眼筋 / 球形嚢
Research Abstract

In order to prepare an animal model of the ocular vestibular evoked myogenic potentials (OVEMP), an intense short tone burst was applied to the unilateral ear of the alert monkeys and evoked responses were evaluated by the surface electrode stuck on the buccal skin. These responses were a negative-positive waveform with a short latency, a high-threshold, contralateral predominance, and influenced by the eye position. These characteristics were similar to those of the OVEMP in humans, suggesting that these buccal responses might be a useful animal model of human OVEMP.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (37 results)

All 2011 2010 2009 2008 Other

All Journal Article (19 results) (of which Peer Reviewed: 19 results) Presentation (15 results) Book (2 results) Remarks (1 results)

  • [Journal Article] Long-term effects of the Meniett device in Japanese patients with Meniere's disease and delayed endolymphatic hydrops reported by the Middle Ear Pressure Treatment Research Group of Japan.2011

    • Author(s)
      Shojaku H, Watanabe Y, Mineta H, et al.
    • Journal Title

      Acta Otolaryngol(Stockh) 131

      Pages: 277-283

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Long-term effects of the Meniett device in Japanese patients with Meni ere's disease and delayed endolymphatic hydrops reported by the Middle Ear Pressure Treatment Research Group of Japan.2011

    • Author(s)
      Shojaku H, Watanabe Y, Mineta H, et al.
    • Journal Title

      Acta Otolaryngol (Stockh)

      Volume: 131 Pages: 277-283

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical characteristics of delayed endolymphatic hydrops in Japan: a nation-wide survey by the Peripheral Vestibular Disorder Research Committee of Japan.2010

    • Author(s)
      Shojaku H, Watanabe Y, Takeda N, et al.
    • Journal Title

      Acta Otolaryngol (Stockh) 130

      Pages: 1135-1140

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 耳石機能検査としてのVEMP2010

    • Author(s)
      將積日出夫
    • Journal Title

      Equilibrium Res 69

      Pages: 168-175

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neural correlates to Seen gaze-direction and head orientation in the macaque monkey amygdala.2010

    • Author(s)
      Tazumi T., Hori E., R S.Maior., Ono T., Nishijo N.
    • Journal Title

      Neuroscience 169

      Pages: 287-301

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] The monkey pulvinar neurons differentially respond to emotional expressions of human faces.2010

    • Author(s)
      Maior RS, Hori E, Tomaz C, Ono T, Nishijo H.
    • Journal Title

      Behav Brain Res 215

      Pages: 129-135

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of acupuncture on the brain hemodynamics.2010

    • Author(s)
      Hori E, Takamoto K, Urakawa S, Ono T, Nishijo H.
    • Journal Title

      Autonomic Neurosci-Basic 157

      Pages: 74-80

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Clinical characteristics of delayed endolymphatic hydrops in Japan : a nation-wide survey by the Peripheral Vestibular Diaorder Research Comm ittee of Japan.2010

    • Author(s)
      Shojaku H, Watanabe Y, Takeda N, et al.
    • Journal Title

      Acta Otolaryngol (Stockh)

      Volume: 130 Pages: 1135-1140

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 耳石機能検査としてのVEMP.2010

    • Author(s)
      將積目出夫
    • Journal Title

      Equilibrim Res

      Volume: 69 Pages: 168-175

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Changes in the characteristics of definite Meniere's disease over time in Japan : a long-term survey by the Peripheral Vestibular Disorder Research Committee of Japan, formerly the Meniere's Disease Research Committee of Japan.2009

    • Author(s)
      Shojaku H, Watanabe Y, Yagi T.
    • Journal Title

      Acta Otolaryngol (Stokh) 129

      Pages: 155-160

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Prognosis of inner ear function in pneumolabyrinth : case report and literature review.2009

    • Author(s)
      Tsubota M, Shojaku H, Watanabe Y.
    • Journal Title

      Am J Otolaryngol 30

      Pages: 423-426

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sexual Influence on Gaze-Guided Social Attention.2009

    • Author(s)
      Hori E, Tsunoda M, Takeshima M, Suzuki M, Kurachi M, Ono T, Nishijo H.
    • Journal Title

      Neurobiologia 72

      Pages: 9-20

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Changes in the characteristics of definite Meniere's disease over time in Japan : a long-term survey by the Peripheral Vestibular Disorder Research Committee of Japan, formerly the Meniere's Disease Research Committee of Japan.2009

    • Author(s)
      Shojaku H, et al.
    • Journal Title

      Acta Otolaryngol 129

      Pages: 155-160

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of the vestibular evoked myogenic potential during parabolic flight in humans.2008

    • Author(s)
      Shojaku H, Watanabe Y, Tsubota M, Katayama N.
    • Journal Title

      Exp Brain Res 187

      Pages: 477-481

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mumps virus may damage the vestibular nerve as well as the inner ear.2008

    • Author(s)
      Tsubota M, Shojaku H, Ishimaru I.
    • Journal Title

      Acta Otolarygol (Stockh) 128

      Pages: 644-647

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A primate model of Schizophrenia using chronic PCP treatment.2008

    • Author(s)
      Mao CV, Hori E, Maior RS, Ono T, Nishijo H.
    • Journal Title

      Review Neurosci 19

      Pages: 83-89

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neural correlates to both emotion and cognitive functions in the monkey amygdala.2008

    • Author(s)
      Nishijo H, Hori E, Tazumi T, Ono T.
    • Journal Title

      Behav Brain Res 188

      Pages: 14-23

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of direct Cedrol inhalation into the lower airway on autonomic nervous activity in totally laryngectomized subjects.2008

    • Author(s)
      Umeno K, Hori E, Tsubota M, Shojaku H., et al.
    • Journal Title

      Br J Clin Pharmacol 65

      Pages: 188-196

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of the vestibular evoked myogenic potential during parabolic flight in humans.2008

    • Author(s)
      Shojaku H, et al.
    • Journal Title

      Exp Brain Res : 2008 187

      Pages: 477-481

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 強大音刺激により無麻酔サル眼窩周囲で記録される誘発反応の検討.2010

    • Author(s)
      坪田雅仁, 将積日出夫, 堀悦郎, 他
    • Organizer
      第69回日本めまい平衡医学会総会
    • Place of Presentation
      京都
    • Year and Date
      2010-11-19
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Long-term effects of the Meniett device in Japanese patients with Meniere's disease and delayed endolymphatic hydrops reported by the Middle Ear Pressure Treatment Research Group of Japan.2010

    • Author(s)
      Shojaku H, Watanabe Y, Mineta H.
    • Organizer
      6^<th> International Symposium on Meniere's disease and Innear Ear Disorders.
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2010-11-16
    • Related Report
      2010 Final Research Report
  • [Presentation] 社会的学習に関連したサル内側前頭葉ニューロンの応答2010

    • Author(s)
      堀悦郎, 小野武年, 西条寿夫
    • Organizer
      霊長類研究所共同研究会「社会・報酬・経済と脳」
    • Place of Presentation
      名古屋
    • Year and Date
      2010-11-01
    • Related Report
      2010 Final Research Report
  • [Presentation] Role of the superior colliculus in social behaviors of infant monkeys.2010

    • Author(s)
      Hori E., Maior RS, Tavares M C,Tomaz C, Ono T, Nishijo H
    • Organizer
      Neuro
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-09-01
    • Related Report
      2010 Final Research Report
  • [Presentation] 瞳孔反応と情動2010

    • Author(s)
      堀悦郎, 小野武年, 西条寿夫
    • Organizer
      電子情報通信学会イメージクオリティ研究会
    • Place of Presentation
      富山(基調講演)
    • Year and Date
      2010-08-27
    • Related Report
      2010 Final Research Report
  • [Presentation] Clinical characteristics of delayed endolymphatic hydrops in Japan : a nation-wide survey by the Peripheral Vestibular Disorder Research Committee of Japan.2010

    • Author(s)
      Shojaku H, Watanabe Y, Takeda N, et al.
    • Organizer
      26^<th> Barany Society Meeting.
    • Place of Presentation
      Raykjavik, Iceland.
    • Year and Date
      2010-08-20
    • Related Report
      2010 Final Research Report
  • [Presentation] 幼若サルの社会行動における上丘の役割2010

    • Author(s)
      堀悦郎, Maior RS, Tavares MC, Tomaz C, 小野武年, 西条寿夫
    • Organizer
      包括型脳科学研究推進支援ネットワーク夏のワークショップ
    • Place of Presentation
      札幌
    • Year and Date
      2010-07-27
    • Related Report
      2010 Final Research Report
  • [Presentation] 第68回日本めまい平衡医学会シンポジウム 「VEMP:耳石器機能検査としての位置づけと今後の展開」耳石器機能検査としてのVEMP2009

    • Author(s)
      將積日出夫
    • Organizer
      第68回めまい平衡医学会
    • Place of Presentation
      徳島
    • Year and Date
      2009-11-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] 社会的認知の脳内機構2009

    • Author(s)
      堀悦郎, 小野武年, 西条寿夫
    • Organizer
      第4回日本情動研究会
    • Place of Presentation
      富山
    • Year and Date
      2009-10-24
    • Related Report
      2010 Final Research Report
  • [Presentation] Effects of vestibular nerve section on sound-evoked myogenic potentials in the sternocleidomastoid muscle of monkeys.2008

    • Author(s)
      Tsubota M, Shojaku H, Hori E, et al.
    • Organizer
      25th Barany Society Meeting.
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2008-04-02
    • Related Report
      2010 Final Research Report
  • [Presentation] Epidemiologic characteristics of definite Meniere's disease in Japan.2008

    • Author(s)
      Shojaku H, Watanabe Y, Tsubota M, et al.
    • Organizer
      25th Barany Society Meeting.
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2008-04-02
    • Related Report
      2010 Final Research Report
  • [Presentation] Cortical response to right caloric stimulation detected by functional near infrared spectroscopy (NIRS).2008

    • Author(s)
      Takakura H, Shojaku H, Kobayashi T.
    • Organizer
      25th Barany Society Meeting.
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2008-04-01
    • Related Report
      2010 Final Research Report
  • [Presentation] 放物線飛行中のVEMPの左右差と自律神経症状との関係2008

    • Author(s)
      坪田雅仁, 將積日出夫, 安村佐都紀, 渡辺行雄, 片山直美
    • Organizer
      第67回めまい平衡医学会
    • Place of Presentation
      秋田
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] 社会的な視覚刺激に対するサルの認知過程-視線計測による解析-2008

    • Author(s)
      堀悦郎, Nguyen MN, 浦川将, 小野武年,西条寿夫
    • Organizer
      第55回中部日本生理学会
    • Place of Presentation
      愛知
    • Related Report
      2010 Final Research Report
  • [Presentation] 皮質下領域のニューロンによる社会的認知.大脳皮質-大脳基底核連関と前頭葉機能(第2回)2008

    • Author(s)
      堀悦郎, 西条寿夫
    • Organizer
      生理学研究所研究会
    • Place of Presentation
      岡崎
    • Related Report
      2010 Final Research Report
  • [Book] 「イラスト」めまいの検査[改訂第2版](日本めまい平衡医学会編)(前庭誘発筋電位(VEMP))2009

    • Author(s)
      將積日出夫
    • Publisher
      診断と治療社(東京)
    • Related Report
      2010 Final Research Report
  • [Book] 「イラスト」めまいの検査 前庭誘発筋電位(VEMP)(日本めまい平衡医学会編)2009

    • Author(s)
      將積日出夫
    • Publisher
      診断と治療社
    • Related Report
      2009 Annual Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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