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Cortical brain reactions by multichannel near hemodynamic response to vestibular related stimulations.

Research Project

Project/Area Number 20591976
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Otorhinolaryngology
Research InstitutionUniversity of Toyama

Principal Investigator

WATANABE Yukio  University of Toyama, 大学院・医学薬学研究部(医学), 教授 (10108037)

Co-Investigator(Kenkyū-buntansha) TAKAKURA Hiromasa  富山大学, 大学院・医学薬学研究部(医学), 助教 (50345576)
UMENO Katsumi  富山大学, 大学院・医学薬学研究部(医学), 助教 (90086596)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords機能的近赤外分光法 / 双極子追跡法 / 前庭刺激 / 脳高次機能
Research Abstract

In order to evaluate the higher brain function related to the circular vection (CV), cortical hemodynamic responses to optokinetic (OK) stimulation detected by multichannel near infrared spectroscopy (NIRS) system were measured in the healthy subjects. OK stimulation in horizontal direction presented increase of hemodynamic response in the vestibular related brain areas, but decrease in the visual related brain areas. Directional changes of OK stimulation between horizontal and vertical axes showed some differences in the hemodynamic responses within the vestibular related brain areas.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (26 results)

All 2010 2009 2008 Other

All Journal Article (17 results) (of which Peer Reviewed: 17 results) Presentation (6 results) Book (2 results) Remarks (1 results)

  • [Journal Article] Clinical characteristics of delayed endolymphatic hydrops in Japan: a nation-wide survey by the Peripheral Vestibular Disorder Research Committee of Japan.2010

    • Author(s)
      Shojaku H, Watanabe Y, Takeda N, Ikezono T, Takahashi M, Kakigi A, Ito J, Doi K, Suzuki M, Takumida M, Takahashi K, Yamashita H, Koizuka I, Usami S, Aoki M, Naganuma H
    • Journal Title

      Acta Otolaryngol (Stockh) 130

      Pages: 1135-1140

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Correlation between canal paresis and spontaneous nystagmus during early stage of acute peripheral vestibular disorders.2010

    • Author(s)
      伏木宏彰, Ishida M, Sumi S, Naruse A, Watanabe Y
    • Journal Title

      Acta Otolaryngol 130

      Pages: 1352-1357

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Directional preponderance of vertical eye movements induced by cross-axis adaptation of the vestibulo-ocular reflex in the cat.2010

    • Author(s)
      Fushiki H, Maruyama M, Watanabe Y
    • Journal Title

      Auris Nasus Larynx 37

      Pages: 570-574

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Prognosis of sudden low-tone loss other than acute low-tone sensorineural hearing loss.2010

    • Author(s)
      Fushiki H, Junicho M, Kanazawa Y, Aso S, Watanabe Y
    • Journal Title

      Acta Otolaryngol 130

      Pages: 559-564

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 小児めまい症例の疾患分類と平衡機能検査.2010

    • Author(s)
      上田直子, 浅井正嗣, 渡邉行雄
    • Journal Title

      Equilibrium Res 69

      Pages: 39-46

    • NAID

      10026088660

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Changes in the characteristics of definite Meniere's disease over time in Japan: a long-term survey by the Peripheral Vestibular Disorder Research Committee of Japan, formerly the Meniere's Disease Research Committee of Japan.2009

    • Author(s)
      Shojaku H, Watanabe Y, Yagi T, Takahashi M, Takeda T, Ikezono T, Ito J, Kubo T, Suzuki M, Takumida M, Takeda N, Furuya N, Yamashita H.
    • Journal Title

      Acta Otolaryngol (Stokh) 129

      Pages: 155-160

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Recurrence rate of idiopathic sudden low-tone sensorineural hearing loss without vertigo : a long-term follow-up study.2009

    • Author(s)
      Fushiki H, Junicho M, Aso S, Watanabe Y
    • Journal Title

      Otol Neurotol 30

      Pages: 295-298

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Global synchronization in the theta band during mental imagery of navigation in humans.2009

    • Author(s)
      Li Y, Umeno K, Hori E, Takakura H, Urakawa S, Ono T, Nishijo H
    • Journal Title

      Neuroscience Research 65

      Pages: 44-52

    • NAID

      10027500249

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Global synchronization in the theta band during mental imagery of navigation in humans.2009

    • Author(s)
      Li Y, Umeno K, Hori E, Takakura H, Urakawa S, Ono T, Nishijo H.
    • Journal Title

      Acta Otolaryngol 65

      Pages: 44-52

    • NAID

      10027500249

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of direct Cedrol inhalation into the lower airway on autonomic nervous activity in totally laryngectomized subjects.2008

    • Author(s)
      Umeno K, Hori E, Tsubota M, Shojaku H, Miwa T, Nagagshima Y, Yada Y, Suzuki T, Ono T, Nishijo H.
    • Journal Title

      Br J Clin Pharmacol 65

      Pages: 188-196

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of the vestibular evoked myogenic potential during parabolic flight in humans.2008

    • Author(s)
      Shojaku H, Watanabe Y, Tsubota M, Katayama N.
    • Journal Title

      Exp Brain Res 187

      Pages: 477-481

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Prognosis of low-tone sudden deafnessdoes it inevitably progress to Meniere's disease?2008

    • Author(s)
      Junicho M, Aso S, Fujisaka M, Watanabe Y
    • Journal Title

      Acta Otolaryngol 128

      Pages: 304-308

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Prognostic value of initial electronystagmography findings in idiopathic sudden sensorineural hearing loss without vertigo.2008

    • Author(s)
      Junicho M, 伏木宏彰, Aso S, Watanabe Y
    • Journal Title

      Otol Neurotol 29

      Pages: 905-909

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 注視眼振検査を指標とした末梢前庭障害の病状把握と急性期治療の検討.2008

    • Author(s)
      伏木宏彰, 渡邉行雄
    • Journal Title

      Equilibrium Res. 67

      Pages: 188-193

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Self-motion perception during conflicting visual-vestibular acceleration.2008

    • Author(s)
      Ishida M, 伏木宏彰, Nishida H, Watanabe Y
    • Journal Title

      J Vestib Res 18

      Pages: 267-272

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of the vestibular evoked myogenic potential during parabolic flight in humans.2008

    • Author(s)
      Shojaku H, Watanabe Y, Tsubota M, Katayama N
    • Journal Title

      Exp Brain Res. 187

      Pages: 477-481

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prognosis of low-tone sudden deafness-does it inevitably progress to Meniere's disease?2008

    • Author(s)
      Junicho M, Aso S, Fujisaka M, Watanabe Y
    • Journal Title

      Acta Otolaryngol 128

      Pages: 304-308

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 近赤外線分光法(NIRS)を用いた視運動性刺激に対する中枢応答の解析-水平刺激と垂直刺激との比較-2010

    • Author(s)
      高倉大匡, 將積日出夫, 西条寿夫, 渡邉行雄
    • Organizer
      第69回日本めまい平衡医学会
    • Place of Presentation
      京都
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 近赤外線分光法(NIRS)を用いた視運動性刺激に対する中枢応答の解析2009

    • Author(s)
      高倉大匡, 將積日出夫, 西条寿夫, 渡邉行雄
    • Organizer
      第68回日本めまい平衡医学会
    • Place of Presentation
      徳島
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] 放物線飛行中の自律神経症状と自覚的視性垂直位・水平位との関係2009

    • Author(s)
      坪田雅仁, 將積日出夫, 渡邉行雄, 安村佐都紀, 片山直美
    • Organizer
      第68回日本めまい平衡医学会
    • Place of Presentation
      徳島
    • Related Report
      2010 Final Research Report
  • [Presentation] 放物線飛行中の自律神経症状と自覚的視性垂直位・水平位との関係.2009

    • Author(s)
      坪田雅仁, 将積日出夫, 渡邉行雄, 安村佐都紀, 片山直美
    • Organizer
      第68回日本めまい平衡医学会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] Vestibular Disorders in Sudden Sensorineural Hearing Loss : Prognostic Value of Initial ENG Findings for Progression to Meniere's Disease.2008

    • Author(s)
      Watanabe Y, Fushiki H, Junicho M, Aso S
    • Organizer
      25th Barany Society Meeting
    • Place of Presentation
      Kyoto
    • Related Report
      2010 Final Research Report
  • [Presentation] Cortical Response to Right Caloric Stimulation Detected by Functional Near Infrared Spectroscopy(fNIRS).2008

    • Author(s)
      Takakura H, Shojaku H, Kobayashi T, Umeno K, Nishijo H, Watanabe Y
    • Organizer
      25th Barany Society Meeting
    • Place of Presentation
      Kyoto
    • Related Report
      2010 Final Research Report
  • [Book] 医療・基礎・症候の論文集2011(めまいの病態生理.)(医療情報科学研究所編)2010

    • Author(s)
      渡邉行雄
    • Publisher
      メディックメディア
    • Related Report
      2010 Final Research Report
  • [Book] 医療・基礎・症候の論文集20112010

    • Author(s)
      渡遷行雄
    • Total Pages
      326
    • Publisher
      メディックメァィア
    • Related Report
      2010 Annual Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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