MicroRNA profiling in drug-resistant head and neck cancer cells.

• Project/Area Number: 20592007
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Otorhinolaryngology
• Research Institution: Hokkaido University
• Principal Investigator: ORIDATE Nobuhiko Hokkaido University, 大学院・医学研究科, 准教授 (90312355)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: マイクロRNA

Research Abstract

MicroRNA profiling was performed between the anticancer drug sensitive- and resistant- head and neck cancer cells to identify microRNAs associated with drug resistant mechanisms.

Research Products

• [Journal Article] Radiotherapy for glottic T1N0 carcinoma with slight hypofractionation and standard overall treatment time : importance of overall treatment time. (2011)
  • Author(s): Onimaru R, Hasegawa M, Yasuda K, Homma A, Oridate N, Fukuda S, Shirato H
  • Journal Title: Jpn J Clin Oncol 41 Pages: 103-109
  • Peer Reviewed
• [Journal Article] Radiotherapy for glottic T1N0 carcinoma with slight hypofractionation and standard overall treatment time: importance of overall treatment time. (2011)
  • Author(s): Onimaru R, Hasegawa M, Yasuda K, Homma A, Oridate N, Fukuda S, Shirato H.
  • Journal Title: Jpn J Clin Oncol. Volume: 41 Pages: 183-109
  • Peer Reviewed
• [Journal Article] Importance of comorbidity in hypopharyngeal cancer. (2010)
  • Author(s): Homma A, Sakashita T, Oridate N, Suzuki F, Suzuki S, Hatakeyama H, Mizumachi T, Taki S, Fukuda S
  • Journal Title: Head Neck 32 Pages: 148-153
  • Peer Reviewed
• [Journal Article] Salvage surgery for local recurrence after chemoradiotherapy or radiotherapy in hypopharyngeal cancer patients. (2010)
  • Author(s): Taki S, Homma A, Oridate N, Suzuki S, Suzuki F, Sakashita T, Fukuda S
  • Journal Title: Eur Arch Otorhinolaryngol 267 Pages: 1765-1769
  • Peer Reviewed
• [Journal Article] Salvage surgery for local recurrence after chemoradiotherapy or radiotherapy in hypopharyngeal cancer patients. (2010)
  • Author(s): Taki S, Homma A, Oridate N, et at
  • Journal Title: Eur Arch Otorhinolaryngol. Volume: 267 Pages: 1765-1769
  • Peer Reviewed
• [Journal Article] Importance of comorbidity in hypopharyngeal cancer. (2010)
  • Author(s): Homma A, Sakashita T, Oridate N, et al
  • Journal Title: Head Neck. Volume: 32 Pages: 148-153
  • Peer Reviewed
• [Journal Article] 頭頸部癌におけるヒト乳頭腫:頭頸部癌とヒト乳頭腫ウイルス(HPV)頭頸部癌におけるヒト乳頭腫ウイルスによる発癌のメカニズムと検出について (2009)
  • Author(s): 水町貴諭、瀧重成、加納里志、原敏浩、鈴木章之、鈴木清護、本間明宏、折舘伸彦、福田諭、古田康
  • Journal Title: 頭頸部癌 35 Pages: 356-359
  • Peer Reviewed
• [Journal Article] Voice-related quality of life after treatment of laryngeal cancer. (2009)
  • Author(s): Oridate N, Homma A, Suzuki S, Nakamaru Y, Suzuki F, Hatakeyama H, Taki S, Sakashita T, Nishizawa N, Furuta Y, Fukuda S
  • Journal Title: Arch Otolaryngol Head Neck Surg 135 Pages: 363-368
  • Peer Reviewed
• [Journal Article] Superselective high-dose cisplatin infusion with concomitant radiotherapy in patients with advanced cancer of the nasal cavity and paranasal sinuses : a single institution experience. (2009)
  • Author(s): Homma A, Oridate N, Suzuki F, Taki S, Asano T, Yoshida D, Onimaru R, Nishioka T, Shirato H, Fukuda S.
  • Journal Title: Cancer 115 Pages: 4705-4714
  • Peer Reviewed
• [Journal Article] Superselective high-dose cisplatin infusion with concomitant radiotherapy in patients with advanced cancer of the nasal cavity and paranasal sinuses : a single institution experience. (2009)
  • Author(s): Homma A, Oridate N, et al
  • Journal Title: Cancer 115 Pages: 4705-4714
  • Peer Reviewed
• [Journal Article] Voice-related quality of life after treatment of laryngeal cancer. (2009)
  • Author(s): Oridate N, Homma A, et al
  • Journal Title: Arch Otolaryngol Head Neck Surg 135 Pages: 363-368
  • Peer Reviewed
• [Journal Article] 頭頸部癌とヒト乳頭腫ウイルス(HPV)頭頸部癌におけるヒト乳頭腫ウイルスによる発癌のメカニズムと検出について (2009)
  • Author(s): 水町貴諭, 瀧重成, 他
  • Journal Title: 頭頸部癌 35 Pages: 356-359
  • Peer Reviewed
• [Journal Article] p53 expression in concurrent chemoradiotherapy with docetaxel for head and neck squamous cell carcinoma (2009)
  • Author(s): Oridate N, 他
  • Journal Title: Auris Nasus Larynx 36 Pages: 57-63
  • Peer Reviewed
• [Journal Article] The diagnosis and management of globus : a perspective from Japan. (2008)
  • Author(s): Oridate N, Nishizawa N, Fukuda S
  • Journal Title: Curr Opin Otolaryngol Head Neck Surg 16 Pages: 498-502
• [Journal Article] p53 expression in concurrent chemoradiotherapy with docetaxel for head and neck squamous cell carcinoma. (2008)
  • Author(s): Oridate N, Homma A, Higuchi E, Suzuki F, Hatakeyama H, Mizumachi T, Furusawa J, Taki S, Furuta Y, Fukuda S
  • Journal Title: Auris Nasus Larynx 36 Pages: 57-63
  • Peer Reviewed
• [Journal Article] Initial CT findings in early tongue and oral floor cancer as predictors of late neck metastasis. (2008)
  • Author(s): Furusawa J, Oridate N, Suzuki F, Homma A, Furuta, Fukuda S
  • Journal Title: Oral Oncol 44 Pages: 793-797
  • NAID: 120000947312
  • Peer Reviewed
• [Journal Article] Initial CT findings in early tongue and oral floor cancer as predictors of late neck metastasis (2008)
  • Author(s): Furusawa J, Oridate N, 他
  • Journal Title: Oral Oncol 44 Pages: 793-797
  • NAID: 120000947312
  • Peer Reviewed
• [Journal Article] The diagnosis and management of globus : a perspective from Japan (2008)
  • Author(s): Oridate N,, 他
  • Journal Title: Curr Opin Otolaryngol Head Neck Surg 16 Pages: 498-502
• [Presentation] Human Papillomavirus and Oropharyngeal Cancer in Japan. Improved survival ofpatients with human papillomavirus-positive oropharyngeal squamous cell carcinoma in Japan. (2010)
  • Author(s): Mizumachi T
  • Organizer: 114th American Academy of ORL-HNS Annual Meeting & OTO EXPO
  • Place of Presentation: ボストンコンベンションセンター(米国・ボストン)
• [Presentation] Human Papillomavirus and Oropharyngeal Cancer in Japan. Improved survival of patients with human papillomavirus-positive oropharyngeal squamous cell carcinoma in Japan. (2010)
  • Author(s): Mizumachi T
  • Organizer: 114th American Academy of ORE-FINS Annual Meeting & OTO EXPO
  • Place of Presentation: ボストンコンベンションセンター(米国・ボストン)
• [Presentation] 喉頭癌に対する超選択的動注併用放射線療法の治療成績 (2009)
  • Author(s): 瀧重成
  • Organizer: 第33回日本頭頸部癌学会、第30頭頸部手術手技研究会
  • Place of Presentation: ロイトン札幌(札幌市)
  • Year and Date: 2009-06-12
• [Presentation] Voice-Related Quality of Life after Treatment for Laryngeal Cancer. (2008)
  • Author(s): Oridate N, Homma A, Suzuki S, Nakamaru Y, Suzuki F, Hatakeyama H, Taki S, Sakashita T, Nishizawa N, Furuta Y, Fukuda S
  • Organizer: The 7th International Conference on Head and Neck Cancer
  • Place of Presentation: マリオットホテル(San Francisco)
  • Year and Date: 2008-07-20
• [Presentation] Voice-Related Quality of Life after Treatment for Laryngeal Cancer (2008)
  • Author(s): Oridate N, 他
  • Organizer: The 7th International Conference on Head and Neck Cancer
  • Place of Presentation: マリオットホテル(San Francisco)
  • Year and Date: 2008-07-20