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The developmental mechanism of incomitant strabismus based on analysis of the orbital pulley.

Research Project

Project/Area Number 20592044
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Ophthalmology
Research InstitutionOkayama University

Principal Investigator

KONO Reika  岡山大学, 岡山大学病院, 医員 (40301296)

Co-Investigator(Kenkyū-buntansha) OHTSUKI Hiroshi  岡山大学, 大学院・医歯薬学総合研究科, 教授 (70093672)
Project Period (FY) 2008 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords眼科学 / 眼球運動 / 非共同性斜視 / pulley(プリー) / 上斜筋麻痺 / MRI / 外眼筋 / 滑車 / pulley (プリー) / 眼窩結合組織
Research Abstract

(1) The 2-dimensional coordinates of the position of the rectus pulley in normal Japanese subjects were calculated by MRI image analysis, and the pulley position was stable with small variation among the subjects. It was also shown that the influence of the standard surgery for strabismus on the pulley was small, but special surgery had an influence.
(2) The incidences of morphological abnormalities of the tendon and trochlea and muscle belly hypoplasia in the superior oblique tendon in superior oblique palsy were higher in congenital than in idiopathic cases.
(3) Excycloduction was noted in the pulley position on the side with superior oblique palsy, compared to that in the normal subjects, suggesting an increased mechanical influence of oblique muscle dysfunction, being responsible as a causative factor of incomitant strabismus.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (23 results)

All 2012 2011 2010 2009

All Journal Article (11 results) (of which Peer Reviewed: 8 results) Presentation (11 results) Book (1 results)

  • [Journal Article] Effect of oblique muscle surgery on the rectus muscle pulley2011

    • Author(s)
      Okanobu H, Kono R, Ohtsuki H
    • Journal Title

      Jpn J Ophthalmol

      Volume: Vol.55 Pages: 514-524

    • NAID

      10029689019

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 強度近視とプリー、斜視の関係について2011

    • Author(s)
      河野玲華
    • Journal Title

      神経眼科

      Volume: Vol.28 Pages: 297-302

    • Related Report
      2011 Final Research Report
  • [Journal Article] Effect of oblique muscle surgery on the rectus muscle pulley2011

    • Author(s)
      Okanob H, Kono R, Ohtsuki H
    • Journal Title

      Jpn J Ophthalmol

      Volume: 55 Pages: 514-524

    • NAID

      10029689019

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 特集強度近視と神経眼科強度近視とプリー、斜視の関係について2011

    • Author(s)
      河野玲華
    • Journal Title

      神経眼科

      Volume: 28 Pages: 297-302

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Absence of relationship between oblique muscle size and Bielschowsky head tilt phenomenon in clinically diagosed superior oblique palsy2009

    • Author(s)
      Kono R, Okanobu H, Ohtsuki H, Demer JL
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: Vol.50 Pages: 175-179

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Splitting of the extraocular horizontal rectus muscle in congenital cranial dysinnervation disorders.2009

    • Author(s)
      Okanobu H, Kono R, Miyake K, Ohtsuki H
    • Journal Title

      Am J Ophthalmol

      Volume: Vol.147 Pages: 550-556

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 正常者における直筋プリーのMRI画像解析2009

    • Author(s)
      河野玲華
    • Journal Title

      臨床眼科

      Volume: 63巻 Pages: 1537-1541

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] プリーの位置異常2009

    • Author(s)
      河野玲華
    • Journal Title

      眼科臨床紀要

      Volume: 2巻 Pages: 23-32

    • NAID

      10026517728

    • Related Report
      2011 Final Research Report
  • [Journal Article] Absence of relationship between oblique muscle size and Bielschowsky head tilt phenomenon in clinically diagosed superior oblique palsy.2009

    • Author(s)
      Reika Kono
    • Journal Title

      Invest Ophthalmol Vis Sci 50

      Pages: 175-179

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Splitting of the extraocular horizontal rectus muscle in congenital cranial dysinnervation disorders.2009

    • Author(s)
      Hirotaka Okanobu
    • Journal Title

      Am J ophthalmol 147

      Pages: 550-556

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 正常者における直筋プリーのMRI画像解析2009

    • Author(s)
      河野玲華
    • Journal Title

      臨床眼科 63

      Pages: 1537-1541

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 強度近視眼と外眼筋間結合組織(バンド)2012

    • Author(s)
      河野玲華、, 他
    • Organizer
      第5回三海研究会-弱視・斜視・神経眼科研究会
    • Place of Presentation
      岡山
    • Year and Date
      2012-03-10
    • Related Report
      2011 Final Research Report
  • [Presentation] 強度近視眼と外眼筋間結合組織(バンド)2012

    • Author(s)
      河野玲華
    • Organizer
      第5回三海研究会-斜視・弱視・神経眼科研究会-
    • Place of Presentation
      岡山コンベンションセンター(岡山市)
    • Year and Date
      2012-03-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 強度近視とプリーの関係-加齢変化と筋間結合組織-2011

    • Author(s)
      河野玲華、, 他
    • Organizer
      第57回岡大眼科学教室同門会総会ならびに岡大眼科学教室学術講演会
    • Place of Presentation
      岡山
    • Year and Date
      2011-06-05
    • Related Report
      2011 Final Research Report
  • [Presentation] 強度近視とプリーの関係-加齢変化と筋間結合組織-2011

    • Author(s)
      河野玲華
    • Organizer
      第57回岡大眼科学教室同門会総会ならびに岡大眼科学教室学術講演会
    • Place of Presentation
      岡山プラザホテル(岡山市)
    • Year and Date
      2011-06-05
    • Related Report
      2011 Annual Research Report
  • [Presentation] III型Duame症候群の外眼筋画像解析2011

    • Author(s)
      河野玲華、, 他
    • Organizer
      第3回三海研究会.斜視・弱視・神経眼科研究会
    • Place of Presentation
      岡山
    • Year and Date
      2011-02-26
    • Related Report
      2011 Final Research Report
  • [Presentation] III型Duame症候群の外眼筋画像解析2011

    • Author(s)
      河野玲華
    • Organizer
      第3回三海研究会-斜視・弱視・神経眼科研究会-
    • Place of Presentation
      岡山
    • Year and Date
      2011-02-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] 上斜筋腱のMRI形態解析2010

    • Author(s)
      河野玲華、, 他
    • Organizer
      第64回日本臨床眼科学会
    • Place of Presentation
      神戸
    • Year and Date
      2010-11-11
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] MRIによる上斜筋腱の形態解析2010

    • Author(s)
      河野玲華、, 他
    • Organizer
      第56回岡大眼科学教室同門会総会ならびに岡大眼科学教室学術講演会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-23
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 走査型レーザー検眼鏡で4直筋プリーの位置を探る2009

    • Author(s)
      岡信宏隆
    • Organizer
      第63回日本臨床眼科学会
    • Place of Presentation
      福岡
    • Year and Date
      2009-10-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] SLO画像による回旋変化と直筋プリー変化との関係2009

    • Author(s)
      岡信宏隆
    • Organizer
      第55回岡大眼科学教室同門会総会ならびに岡大眼科学教室学術講演会
    • Place of Presentation
      岡山
    • Year and Date
      2009-05-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] 日本人正常者の直筋プリーMRI画像解析と手術による直筋プリーの影響を探る2009

    • Author(s)
      岡信宏隆、河野玲華、, 他
    • Organizer
      第113回日本眼科学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-16
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Book] 眼のサイエンス眼疾患の謎2011

    • Author(s)
      根木昭、, 他
    • Publisher
      文光堂
    • Related Report
      2011 Final Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

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