The effects of tissue perfusion for wound biofilm
Project/Area Number |
20592096
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Plastic surgery
|
Research Institution | Tohoku University |
Principal Investigator |
ATSUSHI Takeda Tohoku University, 病院, 助教 (30333800)
|
Co-Investigator(Kenkyū-buntansha) |
MASAHIRO Tachi 東北大学, 大学院・医学系研究科, 教授 (50312004)
鳥谷部 荘八 東北大学, 病院, 助教 (90375006)
|
Project Period (FY) |
2008 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
Keywords | 創傷治癒 / 感染 / バイオフィルム / TNF-α / 皮膚難治性潰瘍 / 虚血 / 創傷被覆剤 |
Research Abstract |
Inoculation with Pseudomonas aeruginosa had accelerated re-epithelialization in rats wounds. Flow cytometry detected higher levels of TNF-a in the infiltrating neutrophils. Quorum sensing mutant induced delayed wound healing.
|
Report
(4 results)
Research Products
(9 results)