A study about the control of mandibular growth in the facial growth

• Project/Area Number: 20592100
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Plastic surgery
• Research Institution: Fukushima Medical University
• Principal Investigator: KAJIKAWA Akiyoshi Fukushima Medical University, 医学部, 准教授 (70260495)
• Co-Investigator(Kenkyū-buntansha): OKOUCHI Hiromi 福島県立医科大学, 医学部, 助教 (20457790)
• Co-Investigator(Renkei-kenkyūsha): MOCHIZUKI Yasushi 福島県立医科大学, 医学部, 助教 (20595524)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 顎発育 / 下顎骨成長 / 成長制御 / 顔面成長 / 軟骨性骨形成 / 下顎頭移植 / 下顎頭軟骨

Research Abstract

This is a study about the control of mandibular growth using a vascularized mandibular heterotopic transplant model. We histologyically observed the condylar cartilage had disappeared by 14 days after subcutaneous transplantation without external and dynamic stress. However, the mandibular condyle grafted into the acromioclavicular joint showed the keep of the condylar cartilage growth. This result indicates the external and dynamic stress affects the maintenance of the orderly condylar cartilage growth of the mandibular condyle. The dynamic stress is important for control of the mandibular growth.

Research Products

• [Presentation] 顔面の3次元的組織欠損の整容的再建 (2010)
  • Author(s): 梶川明義、上田和毅
  • Organizer: 頭蓋顎顔面外科学会
  • Place of Presentation: 京都
  • Year and Date: 2010-10-28
• [Presentation] 顔面の広範囲欠損再建後の整容的2次再建法 (2008)
  • Author(s): 梶川明義、上田和毅
  • Organizer: 頭蓋顎顔面外科学会
  • Place of Presentation: 盛岡
  • Year and Date: 2008-10-17