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Regenerative medical intervention of pigmented dermatosis.

Research Project

Project/Area Number 20592110
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Plastic surgery
Research InstitutionSt.Marianna University School of Medicine

Principal Investigator

KUMAGAI Norio  St.Marianna University School of Medicine, 医学部, 教授 (30103477)

Co-Investigator(Kenkyū-buntansha) INOUE Hajime  聖マリアンナ医科大学, 医学部, 准教授 (60193603)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords組織培養 / 移植学 / 再生医学 / 発生・分化 / 移植・再生医療 / 細胞・組織
Research Abstract

We attempted to develop the effective and low invasive therapy on giant nevi or de-pigmentation patients The skin of the patients obtained IC was collected from the same skin color area surrounding grafted region. After peeling of pigment anomaly area, the cultured keratinocytes sheets were grafted on the region. The grafted keratinocytes sheet took alive almost all as well as was color match. The operation technique has been routinely applied to a systemic giant nevi and a facial de-pigmentation patient.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (16 results)

All 2010 2009 2008

All Journal Article (9 results) (of which Peer Reviewed: 9 results) Presentation (6 results) Book (1 results)

  • [Journal Article] 膠原病に伴う皮膚潰瘍の治療2010

    • Author(s)
      松崎恭一、熊谷憲夫
    • Journal Title

      PEPARS 39

      Pages: 83-95

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 膠原病に伴う皮膚潰瘍の治療2010

    • Author(s)
      松崎恭一, 他
    • Journal Title

      PEPARS

      Volume: 39 Pages: 25-38

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 慢性創傷の疼痛2010

    • Author(s)
      松崎恭一, 他
    • Journal Title

      PEPARS

      Volume: 39 Pages: 83-95

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 肥厚性瘢痕治療で用いるフイックストンRの再使用における一工夫2010

    • Author(s)
      阿藤晃一, 他
    • Journal Title

      形成外科

      Volume: 53 Pages: 98-100

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 上皮幹細胞を用いた新規治療戦略-難治性皮膚潰瘍治療とあらたな展開-2009

    • Author(s)
      井上 肇、熊谷憲夫
    • Journal Title

      医学のあゆみ別冊 231(11)

      Pages: 1091-1095

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 紫外線照射による転写因子basonuclinの局在の変化2009

    • Author(s)
      松崎恭一,松永由紀子,門谷久仁子,川上民裕,井上肇,熊谷憲夫
    • Journal Title

      日本形成外科学会会誌 29(12)

      Pages: 733-738

    • NAID

      10026106990

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 紫外線照射による転写因子basonuclinの局在の変化2009

    • Author(s)
      松崎恭一, 他
    • Journal Title

      日本形成外科学会誌 29

      Pages: 733-738

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 上皮幹細胞を用いた新規治療戦略-難治性皮膚潰瘍治療と新たな展開-2009

    • Author(s)
      井上肇, 他
    • Journal Title

      医学の歩み 231

      Pages: 1091-1095

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 自家培養表皮移植による巨大色素性母斑の治療2008

    • Author(s)
      熊谷憲夫、大島秀男、松崎恭一、井上 肇
    • Journal Title

      Pepars 24

      Pages: 28-36

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Presentation] 培養表皮による創傷治療2010

    • Author(s)
      熊谷憲夫
    • Organizer
      日本再生医療学会総会
    • Place of Presentation
      広島国際会議場(広島県)
    • Year and Date
      2010-03-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] PRPを用いた培養表皮作成法2009

    • Author(s)
      篠田令奈
    • Organizer
      第1回PRP療法研究会
    • Place of Presentation
      大阪
    • Year and Date
      2009-11-15
    • Related Report
      2010 Final Research Report
  • [Presentation] 多血小板血漿を用いた新規培養表皮作成法2009

    • Author(s)
      篠田令奈
    • Organizer
      第18回日本形成外科学会 基礎学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-10-01
    • Related Report
      2010 Final Research Report
  • [Presentation] 培養表皮細胞からの各種増殖因子産生とHSP誘導に及ぼす胃粘膜保護薬の影響2009

    • Author(s)
      岩本承豪
    • Organizer
      第18回日本形成外科学会 基礎学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-10-01
    • Related Report
      2010 Final Research Report
  • [Presentation] トラニラストによる結合組織増殖因子(CTGF)産生制御2009

    • Author(s)
      井上 肇
    • Organizer
      日本創傷外科学会 総会・学術集会
    • Place of Presentation
      東京
    • Related Report
      2008 Annual Research Report
  • [Presentation] 皮膚再生医療による創傷治療2008

    • Author(s)
      熊谷憲夫
    • Organizer
      第34回日本熱傷学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2008-06-28
    • Related Report
      2010 Final Research Report
  • [Book] 培養表皮による創傷治療 創傷外科に置ける新しいアプローチ(形成外科増刊号)2008

    • Author(s)
      熊谷憲夫、井上肇
    • Publisher
      克誠堂出版(株)
    • Related Report
      2010 Final Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

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