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Functional Anatomy of Descending Projections from the Cerebral Cortex Involved in Control of Mastication

Research Project

Project/Area Number 20592138
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Morphological basic dentistry
Research InstitutionOsaka University

Principal Investigator

YOSHIDA Atsushi  Osaka University, 大学院・歯学研究科, 教授 (90201855)

Co-Investigator(Kenkyū-buntansha) MORITANI Masayuki  森ノ宮医療大学, 保健医療学部, 教授 (80303981)
ONO Takahiro  大阪大学, 大学院・歯学研究科, 准教授 (30204241)
Co-Investigator(Renkei-kenkyūsha) TAKI Ikuro  大阪大学, 大学院・歯学研究科, RA (40467585)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords脳 / 神経 / 解剖 / 歯学 / 咀嚼 / 大脳皮質 / ラット / 神経トレーサー
Research Abstract

Three cortical areas (rostral part of the lateral agranular cortex [r-Agl], rostral part of the medial agranular cortex [r-Agm], rostral part of the primary somatosensory cortex [r-S1]) were found to project directly to the three groups of premotoneuron areas around the trigeminal motor nucleus in the rat. The r-Agl and r-Agm had stronger connections with the motor thalamus, while the r-S1 with the sensory thalamus. Electrical stimulation of the r-Agl and r-S1 induced different patterns of jaw movements, while that of the r-Agm induced no jaw movements. The present study indicated that the r-Agl, r-Agm and r-S1 play different roles in jaw movements.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (23 results)

All 2011 2010 2009 2008 Other

All Journal Article (11 results) (of which Peer Reviewed: 11 results) Presentation (7 results) Book (2 results) Remarks (3 results)

  • [Journal Article] Corticofugal direct projections to primary afferent neurons in the trigeminal mesencephalic nucleus of rats.2010

    • Author(s)
      C Iida, A Oka, M Moritani, T Kato, T Haque, F Sato, M Nakamura, K Uchino, S Seki, Y-C Bae, K Takada, A Yoshida.
    • Journal Title

      Neuroscience 169

      Pages: 1739-1757

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Thalamic afferent and efferent connectivity to cerebral cortical areas with direct projections to identified subgroups of trigeminal premotoneurons in the rat.2010

    • Author(s)
      T Haque, S Yamamoto, Y Masuda, T Kato, F Sato, K Uchino, A Oka, M Nakamura, R Takeda, T Ono, M Kogo, A Yoshida.
    • Journal Title

      Brain Res 1346

      Pages: 69-82

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Thalamic afferent and efferent connectivity to cerebral cortical areas with direct projections to identified subgroups of trigeminal premotoneurons in the rat.2010

    • Author(s)
      T Haque, et al.
    • Journal Title

      Brain Research

      Volume: 1346 Pages: 69-82

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Corticofugal direct projections to primary afferent neurons in the trigeminal mesencephalic nucleus of rats2010

    • Author(s)
      C Iida, et al.
    • Journal Title

      Neuroscience

      Volume: 169 Pages: 1739-1757

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Distribution of premotoneurons for jaw-closing and jaw-opening motor nucleus receiving contacts from axon terminals of primary somatosensory cortical neurons in rats.2009

    • Author(s)
      Chang Z, Haque T, Iida C, Seki S, Sato F, Kato T, Uchino K, Ono T, Nakamura M, Bae Y-C, Yoshida A.
    • Journal Title

      Brain Res 1275

      Pages: 43-53

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Corticofugal projections to trigeminal motoneurons innervating antagonistic jaw muscles in rats as demonstrated by anterograde and retrograde tract-tracing.2009

    • Author(s)
      Yoshida, A., Taki, I., Chang, Z., Iida, C., Haque, T., Tomita, A., Seki, S., Yamamoto, S., Masuda, Y., Moritani, M., Shigenaga, Y.
    • Journal Title

      J.Comp.Neurol. 514

      Pages: 368-386

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Distribution of premotoneurons for jaw-closing and jaw-opening motor nucleus receiving contacts from axon terminals of primary somatosensory cortical neurons in rats2009

    • Author(s)
      Chang Z, et al.
    • Journal Title

      Brain Research 1275

      Pages: 43-53

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Light and electron microscopic analysis of the somata and parent axons innervating the rat upper molar and lower incisor pulp2009

    • Author(s)
      Paik SK, et al.
    • Journal Title

      Neuroscience 162

      Pages: 1279-1286

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Corticofugal projections to trigeminal motoneurons innervating antagonistic jaw muscles in rats as demonstrated by anterograde and retrogradetract-tracing.2009

    • Author(s)
      Yoshida, A, et al.
    • Journal Title

      J. Comp. Neurol. (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] GABA- and glycine-like immunoreactivity in axonal endings presynapti c to the vibrissa afferents in the cat trigeminal interpolar nucleus2008

    • Author(s)
      Moon YS., et al.
    • Journal Title

      Neuroscience 152

      Pages: 138-145

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synaptic transmission from the supratrigeminal region to jaw-closing and jaw-opening motoneurons in developing rats.2008

    • Author(s)
      Nakamura S., et al.
    • Journal Title

      J. Neurophysiol. 100

      Pages: 1885-1896

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] Descending projections from the cerebral cortex to lower brainstem neurons involved in orofacial sensory and motor functions2011

    • Author(s)
      A Yoshida、T Kato
    • Organizer
      第116回日本解剖学会総会・全国学術集会 第88回日本生理学会大会 合同大会
    • Place of Presentation
      パシフィコ横浜、横浜市
    • Year and Date
      2011-03-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] ラット大脳皮質一次体性感覚野ニューロンの三叉神経運動前ニューロンへの投射様態2009

    • Author(s)
      飯田千絵、岡綾香、佐藤文彦、山本雅章、武田理恵子、加藤隆史、吉田篤
    • Organizer
      日本解剖学会近畿支部学術集会
    • Place of Presentation
      奈良県立医科大学(橿原市)
    • Year and Date
      2009-11-28
    • Related Report
      2010 Final Research Report
  • [Presentation] ラット三叉神経運動前ニューロン群に投射する大脳皮質部位と視床との神経連絡2009

    • Author(s)
      山本真也, 他
    • Organizer
      顎口腔機能学会
    • Place of Presentation
      昭和大学 (東京)
    • Year and Date
      2009-11-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] Topographic Projections from Cortex to Trigeminal Premotoneurons in Rats. The promotion of multi-disciplinary research projects2009

    • Author(s)
      Yoshida A., et al.
    • Organizer
      The promotion of multi-disciplinary research projects
    • Place of Presentation
      Nihon University Schoolof Dentistry, Tokyo
    • Year and Date
      2009-02-21
    • Related Report
      2008 Annual Research Report
  • [Presentation] ラット三叉神経運動前ニューロン群に投射する大脳皮質部位と視床との神経連絡2009

    • Author(s)
      山本真也、加藤隆史、増田裕次、佐藤文彦、岡綾香、滝育郎、吉田篤
    • Organizer
      顎口腔機能学会
    • Place of Presentation
      昭和大学(東京)
    • Related Report
      2010 Final Research Report
  • [Presentation] 三叉神経運動前ニューロン群に投射する大脳皮質と視床との神経連絡2009

    • Author(s)
      Tahsinul Haque、山本真也、加藤隆史、増田裕次、佐藤文彦、岡綾香、滝育郎、吉田篤
    • Organizer
      三叉神経領域の感覚-運動統合機構研究会
    • Place of Presentation
      日本大学(軽井沢)
    • Related Report
      2010 Final Research Report
  • [Presentation] 大脳皮質から閉口筋運動前ニューロンならびに開口筋運動前ニューロンへの投射2008

    • Author(s)
      滝育郎、磯貝文彦、関伸一郎、飯田千絵、富田章子、佐藤文彦、加藤隆史、増田裕次、吉田篤
    • Organizer
      三叉神経領域の感覚-運動統合機構研究会
    • Place of Presentation
      新潟大学(新潟)
    • Year and Date
      2008-12-07
    • Related Report
      2010 Final Research Report
  • [Book] 口腔顔面領域の神経解剖学の最前線、生命歯科医学のカッティングエッジ(米田俊之編)2008

    • Author(s)
      吉田篤、森谷正之、山本雅章、滝育郎、飯田千絵、富田章子、山本真也、Tahsin Haque、関伸一郎
    • Publisher
      大阪大学出版会
    • Related Report
      2010 Final Research Report
  • [Book] 生命歯科医学のカッテ. インク・エッジ (米田俊之編)2008

    • Author(s)
      吉田篤, 他
    • Total Pages
      287
    • Publisher
      大阪大学出版会
    • Related Report
      2008 Annual Research Report
  • [Remarks] ホームページ等

    • URL

      http://www.dent.osaka-u.ac.jp/graduate/course/anat2.html

    • Related Report
      2010 Final Research Report
  • [Remarks]

    • URL

      http://www.dent.osaka-u.ac.jp/graduate/course/anat2.html

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.dent.osaka-u.ac.jp/~anat2/

    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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