The role of mobile genetic elements in Porphyromonas gingivalis strain diversity
| Project/Area Number |
20592142
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Morphological basic dentistry
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| Research Institution | Nagasaki University |
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Principal Investigator |
NAITO Mariko Nagasaki University, 大学院・医歯薬学総合研究科, 准教授 (20244072)
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| Co-Investigator(Renkei-kenkyūsha) |
SHOJI Mikio 長崎大学, 大学院・医歯薬学総合研究科, 助教 (10336175)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 口腔細菌学 / 微生物学 / ゲノム / 転移性遺伝子 |
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| Research Abstract |
We revealed that periodontal pathogen, Porphyromonas gingivalis, has the extensive genomic diversity among the strains. CTnPg1 is one of the mobile genetic elements in P.gingivalis. This study shows that CTnPg1 can be transferred between P. gingivalis strains and other bacterial species. These results suggest that CTnPg1 may play important roles for the acquisition of diversity within bacterial species and the adaptability against oral environment.
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Report
(4 results)
Research Products
(28 results)
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[Journal Article] Determination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P.gingivalis.2008
Author(s)
Naito M, Hirakawa H, Yamashita A, Ohara N, Shoji M, Yukitake H, Nakayama K, Toh H, Yoshimura F, Kuhara S, Hattori M, Hayashi T, Nakayama K.
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Journal Title
DNA Res. 15(4)
Pages: 215-225
URL
Related Report
Peer Reviewed
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