• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

The role of mobile genetic elements in Porphyromonas gingivalis strain diversity

Research Project

Project/Area Number 20592142
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Morphological basic dentistry
Research InstitutionNagasaki University

Principal Investigator

NAITO Mariko  Nagasaki University, 大学院・医歯薬学総合研究科, 准教授 (20244072)

Co-Investigator(Renkei-kenkyūsha) SHOJI Mikio  長崎大学, 大学院・医歯薬学総合研究科, 助教 (10336175)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords口腔細菌学 / 微生物学 / ゲノム / 転移性遺伝子
Research Abstract

We revealed that periodontal pathogen, Porphyromonas gingivalis, has the extensive genomic diversity among the strains. CTnPg1 is one of the mobile genetic elements in P.gingivalis. This study shows that CTnPg1 can be transferred between P. gingivalis strains and other bacterial species. These results suggest that CTnPg1 may play important roles for the acquisition of diversity within bacterial species and the adaptability against oral environment.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (28 results)

All 2010 2009 2008 Other

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (20 results) Remarks (1 results)

  • [Journal Article] A protein secretion system linked to bacteroidete gliding motility and pathogenesis.2010

    • Author(s)
      Sato K, Naito M, Yukitake H, Hirakawa H, Shoji M, McBride MJ, Rhodes RG, Nakayama K
    • Journal Title

      Proc Natl Acad Sci USA 107

      Pages: 276-281

    • NAID

      120006984618

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A protein secretion system linked to bacteroidete gliding motility and pathogenesis.2010

    • Author(s)
      Sato K., et al.
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: vol.107 Pages: 276-281

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neutralization of toxic haem by Porphyromonas gingivalis haemoglobin receptor.2010

    • Author(s)
      Nhien NT., et al.
    • Journal Title

      J Biochem

      Volume: Vol.147 Pages: 317-325

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of hemin-binding protein 35(HBP35)in Porphyromonas gingival is : its cellular distribution, thioredoxin activity and role in heme utilization.2010

    • Author(s)
      Shoji M., et al.
    • Journal Title

      BMC Microbiol

      Volume: Vol.10 Pages: 152-152

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tetratricopeptide repeat protein-associated proteins contribute to the virulence of Porphyromonas gingivalis.2010

    • Author(s)
      Kondo Y., et al.
    • Journal Title

      Infect Immun

      Volume: Vol.78 Pages: 2846-2856

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recombinant Porphyromonas gingivalis FimA preproprotein expressed in Escherichia coli is lipidated and a mature or processed recombinant FimA protein forms a short filament in vitro.2010

    • Author(s)
      Shoji M., et al.
    • Journal Title

      Can J Microbiol

      Volume: Vol.56 Pages: 959-967

    • NAID

      120006985158

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Determination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P.gingivalis.2008

    • Author(s)
      Naito M, Hirakawa H, Yamashita A, Ohara N, Shoji M, Yukitake H, Nakayama K, Toh H, Yoshimura F, Kuhara S, Hattori M, Hayashi T, Nakayama K.
    • Journal Title

      DNA Res. 15(4)

      Pages: 215-225

    • URL

      http://naosite.lb.nagasaki-u.ac.jp/dspace/handle/10069/20817

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Presentation] Porphyromonas gingivalisのconjugative transposon CTnPg1の伝達機構の解析2010

    • Author(s)
      内藤真理子, 佐藤啓子, 雪竹英治, 庄子幹郎, 中山浩次
    • Organizer
      第52回歯科基礎医学会学術大会ならびに総会{Journal of Oral Biosciences, 52, Supp.l, p185}
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] Characterization of Porphyromonas gingivalis Conjugative Transposon CTnPg1.2010

    • Author(s)
      Naito M, Sato K, Shoji M, Yukitake H, Hayashi T, Nakayama K
    • Organizer
      88th IADR, Barcelona, {Program, pp160}
    • Place of Presentation
      Spain
    • Related Report
      2010 Final Research Report
  • [Presentation] Porphyromonas gingivalisのconjugative transposon CTnPg1の伝達機構の解析2010

    • Author(s)
      内藤真理子, 佐藤啓子, 雪竹英治, 庄子幹郎, 中山浩次
    • Organizer
      第4回日本ゲノム微生物学会年会{プログラムおよび講演抄録集p59}
    • Place of Presentation
      福岡
    • Related Report
      2010 Final Research Report
  • [Presentation] Characterization of Porphyromonas gingivalis Conjugative Transposon CTnPg1.2010

    • Author(s)
      内藤真理子, 他
    • Organizer
      88th IADR
    • Place of Presentation
      Central Conventions International Barcelona(スペイン バルセロナ)
    • Related Report
      2010 Annual Research Report
  • [Presentation] バクテロイデーテス細菌におけるタンパク分泌、滑走運動および病原性(第22回歯科基礎医学賞受賞講演)2010

    • Author(s)
      佐藤啓子, 他
    • Organizer
      第52回歯科基礎医学会学術大会ならびに総会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Porphyromonas gingivalisにおけるHBP35蛋白を用いた糖鎖修飾機構の解明2010

    • Author(s)
      庄子幹郎, 他
    • Organizer
      第52回歯科基礎医学会学術大会ならびに総会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Tannerella forsythiaのPor分泌機構関連タンパク質欠損株の性状解析2010

    • Author(s)
      成田由香, 他
    • Organizer
      第52回歯科基礎医学会学術大会ならびに総会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 抗菌物質非鉄金属ポルフィリンの取り込みに関与するP.gingivalis外膜タンパク質2010

    • Author(s)
      雪竹英治, 他
    • Organizer
      第52回歯科基礎医学会学術大会ならびに総会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Porphyromonas gingivalisのconjugative transposon CTnPg1の伝達機構の解析2010

    • Author(s)
      内藤真理子, 他
    • Organizer
      第52回歯科基礎医学会学術大会ならびに総会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Determination of the Genome Sequence of Porphyromonas gingivalis Strain ATCC 33277 and Extensive Genome Rearrangements in P.gingivalis2010

    • Author(s)
      内藤真理子
    • Organizer
      平成21年度広島大学大学院医歯薬学総合研究科バイオデンティスト育成プログラム国際ワークショップ
    • Place of Presentation
      広島市広島アステールプラザ
    • Related Report
      2009 Annual Research Report
  • [Presentation] Porphyromonas gingivalisのconjugative transposon CTnPg1の伝達機構の解析2010

    • Author(s)
      内藤真理子(代表)
    • Organizer
      第4回ゲノム微生物学会年会
    • Place of Presentation
      福岡市九州大学歯学部百年講堂
    • Related Report
      2009 Annual Research Report
  • [Presentation] Porphyromonas gingivalisのconjugative transposon CTnPg1の伝達機構の解析2010

    • Author(s)
      内藤真理子(代表)
    • Organizer
      第83回日本細菌学会総会
    • Place of Presentation
      横浜市パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] Porphyromonas gingivalisのtransposon CTnPg1の伝達機構2009

    • Author(s)
      内藤真理子, 佐藤啓子, 雪竹英治, 庄子幹郎, 林哲也, 中山浩次
    • Organizer
      第3回日本ゲノム微生物学会年会{要旨集,p.59}
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] Porphyromonas gingivalisのconjugative transposon CTnPg1の伝達に係る遺伝子の解析2009

    • Author(s)
      内藤真理子(代表)
    • Organizer
      第62回日本細菌学会 九州支部会
    • Place of Presentation
      佐賀市佐賀大学医学部臨床大講堂
    • Related Report
      2009 Annual Research Report
  • [Presentation] Porphyromonas gigivalis のcojugative transposon CTnPglの伝達機構2009

    • Author(s)
      内藤 真理子 (代表)
    • Organizer
      第二回ゲノム微生物学会年会
    • Place of Presentation
      東京都 中央大学工学部
    • Related Report
      2008 Annual Research Report
  • [Presentation] Porphyromonas gigivalis のcojugative transposon CTnPglの伝達機構2009

    • Author(s)
      内藤 真理子 (代表)
    • Organizer
      第82回日本細菌学会総会
    • Place of Presentation
      名古屋市 名古屋国際会議場
    • Related Report
      2008 Annual Research Report
  • [Presentation] 歯周病菌Porphyromonas gigivalis の接合による遺伝子形質の伝達2008

    • Author(s)
      内藤 真理子 (代表)
    • Organizer
      平成20年度九州微生物研究会総会
    • Place of Presentation
      福岡市 ホテルセントラーザ博多
    • Year and Date
      2008-12-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] Porphyromonas gingivalisの接合による遺伝子形質の伝達2008

    • Author(s)
      内藤真理子, 佐藤啓子, 雪竹英治, 庄子幹郎, 中山浩次
    • Organizer
      第50回歯科基礎医学会学術大会ならびに総会{Journal of Oral Biosciences, 50, Suppl., p218}
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] Porphyromonas gigivalis の接合による遺伝子形質の伝達2008

    • Author(s)
      内藤 真理子 (代表)
    • Organizer
      第50回歯科基礎医学学術大会
    • Place of Presentation
      東京都有明コンベンションホール
    • Related Report
      2008 Annual Research Report
  • [Presentation] Porphyromonas gigivalis のcojugative transposon CTnPglによる遺伝子形質の伝達2008

    • Author(s)
      内藤 真理子 (代表)
    • Organizer
      第61回日本細菌学会 九州支部会
    • Place of Presentation
      熊本市 熊本大学山崎記念館
    • Related Report
      2008 Annual Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi