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Lymphatic architecture of the small experimental animals.-Head and neck regions-

Research Project

Project/Area Number 20592144
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Morphological basic dentistry
Research InstitutionIwate Medical University

Principal Investigator

FUJIMURA Akira  Iwate Medical University, 歯学部, 教授 (80173459)

Co-Investigator(Kenkyū-buntansha) 小野寺 政雄  岩手医科大学, 歯学部, 助教 (10326689)
野坂 洋一郎  岩手医科大学, 歯学部, 教授 (60048379)
大澤 得二  岩手医科大学, 歯学部, 講師 (00103747)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords口腔解剖学(含組織学・発生学) / リンパ管構築 / 口腔 / 頭頸部 / 実験動物 / 発生 / マウス頬粘膜 / マウス臼歯歯根膜 / マウス臼歯の発生
Research Abstract

I have studied the detail of lymphatic architecture in the oral region of mouse as a small experimental animal. There were lymphatic vessels in the oral region except for in the periodontal ligament or in the mandible. There were hexagonal network of the lymphatic vessels which had the blind-end lymphatic vessels beneath the mucosal epithelium and the quantity of lymphatic vessels differed in each parts. From the drug administration point of view, the gingiva was good part for drug administration. Especially, I think that the lymphatic vessels in the interdental papilla and beneath the sulcal epithelium were very useful.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (51 results)

All 2011 2010 2009 2008 Other

All Journal Article (20 results) (of which Peer Reviewed: 10 results) Presentation (30 results) Remarks (1 results)

  • [Journal Article] Architecture of blood vessels in the mouse infraorbital nerve.2011

    • Author(s)
      Atsumi Chiba, Akira Fujimura
    • Journal Title

      MVRC 4(1) in press

    • NAID

      130004467812

    • Related Report
      2010 Final Research Report
  • [Journal Article] The distribution of lymphatic vessels in the periodontal ligament during tooth root formation.2011

    • Author(s)
      Munenori Kikuchi, Akira Fujimura
    • Journal Title

      MVRC 4(1) in press

    • NAID

      130004467811

    • Related Report
      2010 Final Research Report
  • [Journal Article]2011

    • Author(s)
      Munenori Kikuchi, 他, (2番目)
    • Journal Title

      Microvascular Research and Communications

      Volume: 4(in press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article]2011

    • Author(s)
      Atsumi Chiba, 他, (2番目)
    • Journal Title

      Microvascular Research and Communications

      Volume: 4(in press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] bFGF徐放性材料を用いた骨再生モデルにおける骨再生と血管新生の検討2011

    • Author(s)
      大橋祐生, 他, (2番目)
    • Journal Title

      岩手医科大学歯学雑誌

      Volume: 36(in press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Lymphatic distribution in the mouse periodontal ligament.2010

    • Author(s)
      Mikiko Masuyama, Akira Fujimura
    • Journal Title

      MVRC 3(1)

      Pages: 2-10

    • NAID

      130004467807

    • Related Report
      2010 Final Research Report
  • [Journal Article] Lymphatic architecture of human periodontal tissue beneath the oral epithelium of the free gingiva.2010

    • Author(s)
      Yoshinori Ando, Akira Fujimura
    • Journal Title

      MVRC 3(1)

      Pages: 17-24

    • NAID

      130004467806

    • Related Report
      2010 Final Research Report
  • [Journal Article] ヒトの皮下リンパ管構築2010

    • Author(s)
      藤村朗, 他1名
    • Journal Title

      リンパ学

      Volume: 33 Pages: 82-86

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Lymphatic distribution in the mouse periodontal ligament.2010

    • Author(s)
      Mikiko Masuyama, 他(2番目)
    • Journal Title

      Microvascular Research and Communications 3

      Pages: 2-10

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Lymphatic architecture of human periodontal tissue beneath the oral epithelium of the free gingival.2010

    • Author(s)
      Yoshinori Ando, 他(2番目)
    • Journal Title

      Microvascular Research and Communications 3

      Pages: 17-24

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 頬粘膜下リンパ管の構築と分布量2009

    • Author(s)
      佐藤大, 藤村朗
    • Journal Title

      岩手歯誌 34(1)

      Pages: 7-17

    • NAID

      110007226264

    • Related Report
      2010 Final Research Report
  • [Journal Article] Protective role of osteopontin in endodontic infection.2009

    • Author(s)
      Rittling SR, 他(6番目)
    • Journal Title

      Immunology PMID:19824920

      Pages: 1-10

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 頬粘膜下リンパ管の構築と分布量2009

    • Author(s)
      佐藤大, 他(2番目)
    • Journal Title

      岩手医科大学歯学雑誌 34

      Pages: 7-17

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 頬粘膜下リンパ管の構築と分布量2009

    • Author(s)
      佐藤 大, 藤村 朗
    • Journal Title

      岩手医科大学歯学雑誌 34(in press)

    • NAID

      110007226264

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Lymphatic distribution in the mouse periodontal ligament.2009

    • Author(s)
      Masuyama, M. Fujimura, A.
    • Journal Title

      Micrivascular Research and Communications. 3(in press)

    • NAID

      130004467807

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The distribution of lymphatic vessels in gingiva.2008

    • Author(s)
      Min-Ying Liao, Akira Fujimura
    • Journal Title

      MVRC 2(1)

      Pages: 2-7

    • NAID

      130004942916

    • Related Report
      2010 Final Research Report
  • [Journal Article] 口腔領域のリフア禰築-薬剤投与経路としての応用-2008

    • Author(s)
      藤村朗, 野坂洋一郎
    • Journal Title

      リンパ学 31

      Pages: 2-5

    • Related Report
      2010 Final Research Report
  • [Journal Article] Quantitative Analysis of Very Small Quantity of Organs Taken from Patients and Experimental Animals ; Standard-free Method for Organ Samples.2008

    • Author(s)
      Sera, K., Itoh, J., Goto, S., Sait oh, Y., Fujimura, A., Nosaka Y., Noda, Y., Nishizuka, S., Wakabayashi, G.
    • Journal Title

      Int'l Journal of PIXE 18-3,4

      Pages: 111-122

    • Related Report
      2010 Final Research Report
  • [Journal Article] The distribution of lymphatic vessels in gingiva.2008

    • Author(s)
      Liao, M-Y., Fujimura, A.
    • Journal Title

      Micrivascular Research and Communications. 2

      Pages: 1-6

    • NAID

      130004942916

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 口腔領域のリンパ管構築-薬剤投与経路としての応用-2008

    • Author(s)
      藤村 朗野坂 洋一郎
    • Journal Title

      リンパ学 31

      Pages: 2-5

    • Related Report
      2008 Annual Research Report
  • [Presentation] Architecture of blood vessels in the mouse infraorbital nerve.2011

    • Author(s)
      Atsumi Ishizuka, 他, (3番目)
    • Organizer
      第36回日本微小循環学会総会
    • Place of Presentation
      名古屋
    • Related Report
      2010 Annual Research Report
  • [Presentation] Lymphatic architecture of human periodontal tissue beneath the oral epithelium of the free gingiva.2011

    • Author(s)
      Yoshinori Ando, 他, (3番目)
    • Organizer
      The 116th Annual Meeting of the Japanese Association of Anatomists
    • Place of Presentation
      Yokohama, Japan
    • Related Report
      2010 Annual Research Report
  • [Presentation] The development of sustained release preparation. -Local damini stration using the lymphatic system-2010

    • Author(s)
      Akira Fujimura, 他
    • Organizer
      第35回日本微小循環学会
    • Place of Presentation
      大宮ソニックシティ
    • Year and Date
      2010-02-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] 頭頸部領域の排導系2010

    • Author(s)
      藤村朗
    • Organizer
      第115回日本解剖学会全国学術学会
    • Related Report
      2010 Final Research Report
  • [Presentation] The development of sustained release preparation.-Local administrationusing the lymphatic system-2010

    • Author(s)
      Akira Fujimura, Ikumi Sugiyama, Yasuyuki Sadzuka, Yohichiro Nozaka
    • Organizer
      第35回日本微小循環学会
    • Related Report
      2010 Final Research Report
  • [Presentation] Lymphatic architecture of human gingiva-free gingiva-2010

    • Author(s)
      Yoshinori Ando, 他, (2番目)
    • Organizer
      The 96th Annual Meeting of AAP in collaboration with JSP
    • Place of Presentation
      Honolulu, Hawaii
    • Related Report
      2010 Annual Research Report
  • [Presentation] ヒトの皮下リンパ管構築2010

    • Author(s)
      藤村朗, 他
    • Organizer
      第34回日本リンパ学会総会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] Suncus murinus口腔粘膜下リンパ管構築-舌-2010

    • Author(s)
      安藤禎紀, 他, (4番目)
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] 破骨細胞におけるcalpain-slingshotを介したアクチンリング制御について2010

    • Author(s)
      鍵谷忠慶, 他, (3番目)
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] 頭頸部領域の排導系(シンポジウム頭頸部領域の臨床解剖学)2010

    • Author(s)
      藤村朗
    • Organizer
      第115回日本解剖学会全国学術学会
    • Place of Presentation
      盛岡
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒト顔面の皮下リンパ管構築2009

    • Author(s)
      藤村朗, 他
    • Organizer
      第33回日本リンパ学会総会
    • Place of Presentation
      大阪医科大学
    • Year and Date
      2009-07-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] 神経ブロック後の眼窩下神経再生に伴う血管構築変化-健常マウスの眼窩下神経内血管構築-2009

    • Author(s)
      千葉淳実、藤村朗、鹿島悠子、鎌田俊、佐藤雅仁、野坂洋一郎、城茂治
    • Organizer
      第37回日本歯科麻酔学会学術集会
    • Related Report
      2010 Final Research Report
  • [Presentation] 顔面皮下のリンパ管分布2009

    • Author(s)
      藤村朗、小野寺政雄、大澤得二、野坂洋一郎
    • Organizer
      日本解剖学会第55回東北・北海道連合支部学術集会
    • Related Report
      2010 Final Research Report
  • [Presentation] 歯周組織のリンパ管構築の発生2009

    • Author(s)
      菊池宗法、藤村朗、小野寺政雄、大澤得二、清野幸男、野坂洋一郎、三浦廣行
    • Organizer
      第51回歯科基礎医学会学術大会
    • Related Report
      2010 Final Research Report
  • [Presentation] ヒト顔面の皮下リンパ管構築2009

    • Author(s)
      藤村朗、安藤禎紀、菊池宗法、千葉淳美、桑島幸紀、小野寺政雄、野坂洋一郎
    • Organizer
      第33回日本リンパ学会総会
    • Related Report
      2010 Final Research Report
  • [Presentation] Lymphatic vessels in healthy and diseased human gingiva.2009

    • Author(s)
      安藤禎紀, 千葉淳美, 小野寺政雄, 藤村朗, 國松和司, 野坂洋一郎
    • Organizer
      第34回日本微小循環学会
    • Related Report
      2010 Final Research Report
  • [Presentation] 歯周組織のリンパ管構築の発生2009

    • Author(s)
      菊池宗法, 他(2番目)
    • Organizer
      第51回歯科基礎医学会学術大会
    • Place of Presentation
      新潟市 朱鷺メッセ
    • Related Report
      2009 Annual Research Report
  • [Presentation] 顔面皮下のリンパ管分布2009

    • Author(s)
      藤村朗, 他
    • Organizer
      日本解剖学会第55回東北・北海道連合支部学術集会
    • Place of Presentation
      仙台
    • Related Report
      2009 Annual Research Report
  • [Presentation] Lymphatic architecture of the interdental papilla in human gingiva.2009

    • Author(s)
      Ando Y., 他(2番目)
    • Organizer
      2009 Autumn Scientific Meeting of KACD and The 11th Scientific joint meeting between JSCD and KACD
    • Place of Presentation
      Jeju, Korea
    • Related Report
      2009 Annual Research Report
  • [Presentation] Lymphatic vessels in healthy and diseased human gingival.2009

    • Author(s)
      Y. Ando, A. Chiba, M. Onodera, A. Fujimura, K. Kunimatsu, Y. Nozaka
    • Organizer
      第34回日本微小循環学会総会
    • Place of Presentation
      東京
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヒト歯肉のリンパ管構築-正常と病態-2008

    • Author(s)
      安藤禎紀、藤村朗、村井治、野坂洋一郎、國松和司
    • Organizer
      第51回秋季日本歯周病学会学術大会
    • Related Report
      2010 Final Research Report
  • [Presentation] ウサギ耳介のリンパ管構築2008

    • Author(s)
      藤村朗、安藤禎紀、古城慎太郎、香木千尋、小野寺政雄、大澤得二、野坂洋一郎
    • Organizer
      第50回歯科基礎医学会学術大会
    • Related Report
      2010 Final Research Report
  • [Presentation] 口腔領域のリンパ管構築-マウス上顎舌側歯肉一2008

    • Author(s)
      藤村朗、安藤禎紀、佐藤弘樹、佐藤大、小野寺政雄、野坂洋一郎
    • Organizer
      第32回日本リンパ学会総会
    • Related Report
      2010 Final Research Report
  • [Presentation] 頬粘膜および口蓋粘膜経由の抗癌剤投与2008

    • Author(s)
      藤村朗、野坂洋一郎、世良耕一郎
    • Organizer
      第14回NMCC共同利用研究成果発表会
    • Related Report
      2010 Final Research Report
  • [Presentation] 口腔領域のリンパ管構築-薬剤投与経路としての臨床応用-2008

    • Author(s)
      藤村朗, 小野寺政雄、野坂洋一郎
    • Organizer
      第113回日本解剖学会全国学術学会
    • Related Report
      2010 Final Research Report
  • [Presentation] 頬粘膜および口蓋粘膜経由の抗癌剤投与2008

    • Author(s)
      藤村 朗, 野坂 洋一郎世良耕一郎
    • Organizer
      第14回NMCC共同利用研究成果発表会
    • Place of Presentation
      盛岡
    • Related Report
      2008 Annual Research Report
  • [Presentation] 口腔領域のリンパ管構築 -マウス上顎舌側歯肉-2008

    • Author(s)
      藤村 朗, 安藤 禎紀, 佐藤 弘樹, 佐藤 大, 小野寺 政雄, 野坂 洋一郎
    • Organizer
      第32回日本リンパ学会総会
    • Place of Presentation
      東京
    • Related Report
      2008 Annual Research Report
  • [Presentation] Morphological changes of infraorbital nerve by nerve block.2008

    • Author(s)
      S. Joh, Y. Kashima, A. Fujimura, M. Satoh, Y. Shinohe
    • Organizer
      IADR 86th General Session
    • Place of Presentation
      Toronto, Ontario, Canada
    • Related Report
      2008 Annual Research Report
  • [Presentation] 歯の移動時のリンパ管構築の変化に関する研究第2報 正常マウス歯根膜のリンパ管構築2008

    • Author(s)
      増山美樹子, 藤村朗, 野坂洋一郎, 清野幸男, 三浦廣行
    • Organizer
      第67回日本矯正歯科学会大会
    • Place of Presentation
      千葉
    • Related Report
      2008 Annual Research Report
  • [Presentation] ウサギ耳介のリンパ管構築2008

    • Author(s)
      藤村 朗, 安藤 禎紀, 古城 慎太郎, 香木 千尋, 小野寺 政雄, 大澤 得二, 野坂 洋一郎
    • Organizer
      第50回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Related Report
      2008 Annual Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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