| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Research Abstract |
In the present study, the expressions of microRNA (miRNA) was analyzed during the embryonic development of mouse tongue muscle. The expression levels of miR-1 and 24 increased with the embryonic development and peaked between embryonic day (E) 13 and 15 during which tongue muscle cells are actively differentiating. On the contrary, those of miR-199a and 199b peaked at the beginning of the tongue muscle development (E11) and decreased thereafter. These results suggest that miR-1 and 24 are involved in the differentiation of tongue muscle cells.
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