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New approaches for antimicrobial strategies for biofilm in infected root canal

Research Project

Project/Area Number 20592223
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Conservative dentistry
Research InstitutionNiigata University

Principal Investigator

TAKENAKA Shoji  Niigata University, 医歯学系, 助教 (50313549)

Co-Investigator(Kenkyū-buntansha) YOSHIBA Kunihiko  新潟大学, 医歯学系, 准教授 (30220718)
OKIJI Takashi  新潟大学, 医歯学系, 教授 (80204098)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordsバイオフィルム / 共焦点レーザー顕微鏡 / 感染根管 / 生死判別 / 浸透 / 拡散
Research Abstract

The overall success rate of conventional root canal treatment has been shown to range from about 65 % to 95%. Recently, some new technologies have been developed for the purpose of effective elimination of infected regions, efficiency of treatment, and reduction of treatment period. The estimation of these technologies are needed for clinical use. A new technology has been developed for artificial root infected model and estimation of root canal treatment.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (34 results)

All 2011 2010 2009 2008

All Journal Article (15 results) (of which Peer Reviewed: 12 results) Presentation (19 results)

  • [Journal Article] 人工バイオフィルム深層部への各種高分子化合物の拡散性.2011

    • Author(s)
      竹中彰治、Betsey Pitts, 若松里佳、大墨竜也、Philip Stewart, 興地隆史
    • Journal Title

      Bacterial Adherence & Biofilm 23 in press

    • Related Report
      2010 Final Research Report
  • [Journal Article] 人工バイオフィルム深層部への各種高分子化合物の拡散性2011

    • Author(s)
      竹中彰治、若松里佳, ほか
    • Journal Title

      Bacterial Adherence & Biofilm

      Volume: 23(In press)

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 高齢者の口腔機能の評価と管理のシステム化に関する研究第1報自立者の総合的な検査法、改善法、効果の評価法ついて2009

    • Author(s)
      武井典子, 藤本篤士, 木本恵美子, 竹中彰治, 福島正義, 奥瀬敏之, 岩久正明, 石川正夫, 高田康二
    • Journal Title

      老年歯科医学 23(4)

      Pages: 384-396

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 新規歯面コーティング材の短期的臨床評価.2009

    • Author(s)
      竹中彰治、小林千夏、若松里佳、福島正義、興地隆史
    • Journal Title

      歯科審美 22

      Pages: 41-47

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 新規歯面コーティング材塗布のアンケートによる審美性評価.2009

    • Author(s)
      若松里佳、竹中彰治、本間春菜、尾添裕美子、福島正義、興地隆史
    • Journal Title

      歯科審美 21

      Pages: 22-29

    • NAID

      10025693580

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Diffusion of macromolecules in model oral biofilms.2009

    • Author(s)
      Takenaka S, Trivedi HM, Pitts B, Stewart PS
    • Journal Title

      Appl Environ Microbiol 75

      Pages: 1750-1753

    • NAID

      10020162565

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Translucency and color change of tooth-colored temporary coating materials.2009

    • Author(s)
      Takenaka S, Wakamatsu R, Ozoe Y, Tomita F, Fukushima M, Okiji T.
    • Journal Title

      Am J Dent 22(6)

      Pages: 361-365

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Diffusion of Macromolecules in Model Oral Biofilms2009

    • Author(s)
      S.Takenaka, et al.
    • Journal Title

      Applied and Environmental Microbiology 75

      Pages: 1750-1753

    • NAID

      10020162565

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Translucency and color change of tooth-colored temporary coating materials.2009

    • Author(s)
      S.Takenaka, et al.
    • Journal Title

      Am J Dent 22

      Pages: 361-365

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Diffusion of Macromolecules in Model Oral Biofilms2009

    • Author(s)
      S. Takenaka, et al.
    • Journal Title

      Applied and Environmental Microbiology 75

      Pages: 1750-1753

    • NAID

      10020162565

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 口腔における成熟バイオフィルムの制御戦略.2008

    • Author(s)
      竹中彰治、興地隆史
    • Journal Title

      Bacterial Adherence & Biofilm 22

      Pages: 1-6

    • Related Report
      2010 Final Research Report
  • [Journal Article] Direct visualization of spatial and temporal patterns of antimicrobial action within model oral biofilms.2008

    • Author(s)
      Takenaka S, Trivedi HM, Corbin A, Pitts B, Stewart PS
    • Journal Title

      Appl Environ Microbiol 74(6)

      Pages: 1869-1875

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Removal of Resin-based Root Canal Filling Materials with K3 Rotary Instruments : Relative Efficacy for Different Combinations of Filling Materials.2008

    • Author(s)
      Iizuka N, Takenaka S, Shigetani Y, Okiji T.
    • Journal Title

      Dent Mater J. 27(1)

      Pages: 75-80

    • NAID

      110006570542

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Streptococcus mutans on the generation of fluorescence from artificially-induced enamel and dentin carious lesions in vitro.2008

    • Author(s)
      Shigetani Y, Takenaka S, Okamoto A, Abu-Bakr N, Iwaku M, Okiji T.
    • Journal Title

      Odontology 96(1)

      Pages: 21-25

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] レジン系根管充填材料の封鎖性および接着性-固形根管充填材・シーラー界面に対する検討-.2008

    • Author(s)
      重谷佳見, 竹中彰治, 飯塚直之, 興地隆史
    • Journal Title

      日歯内療誌 29(1)

      Pages: 30-36

    • NAID

      10024185507

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Presentation] 口腔バイオフィルムに対する各種含嗽剤の浸透性について.2010

    • Author(s)
      若松里佳、竹中彰治、大墨竜也、興地隆史
    • Organizer
      バイオフィルム研究会
    • Place of Presentation
      富士宮
    • Year and Date
      2010-09-11
    • Related Report
      2010 Final Research Report
  • [Presentation] 口腔バイオフィルムに対する各種含漱剤の浸透性について2010

    • Author(s)
      若松里佳、竹中彰治, ほか
    • Organizer
      バイオフィルム研究会
    • Place of Presentation
      富士宮
    • Year and Date
      2010-09-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] 人工バイオフィルム深層部への各種高分子化合物の拡散性について.2010

    • Author(s)
      竹中彰治、Betsey Pitts, 若松里佳、大墨竜也、Philip Stewart, 興地隆史
    • Organizer
      第24回Bacterial Adherence & Biofilm 学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-09
    • Related Report
      2010 Final Research Report
  • [Presentation] 人工バイオフィルム深層部への各種高分子化合物の拡散性について2010

    • Author(s)
      竹中彰治、若松里佳, ほか
    • Organizer
      Bacterial Adherence & Biofilm学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] Comparison of different experimental techniques for visualizing viability of biofilm bacteria.2010

    • Author(s)
      Ohsumi T, Takenaka S, Wakamatsu R, Okiji T.
    • Organizer
      International Joint Symposium on Oral Science.
    • Place of Presentation
      Bali, Indonesia
    • Related Report
      2010 Final Research Report
  • [Presentation] in vitro バイオフィルムモデル形成能と含嗽剤の殺菌効果.2010

    • Author(s)
      若松里佳、竹中彰治、大墨竜也、福田敬、富田文仁、興地隆史
    • Organizer
      日本歯科保存学会秋季学術大会(第133回)
    • Place of Presentation
      岐阜
    • Related Report
      2010 Final Research Report
  • [Presentation] Comparison of different experimental techniques for visualizing viability of biofilm bacteria.2010

    • Author(s)
      Ohsumi T, Takenaka S, et al
    • Organizer
      International Joint Symposium on Oral Science
    • Place of Presentation
      Bali, Indonesia
    • Related Report
      2010 Annual Research Report
  • [Presentation] in vitroバイオフィルムモデル形成能と含漱剤の殺菌効果2010

    • Author(s)
      若松里佳、竹中彰治, ほか
    • Organizer
      日本歯科保存学会
    • Place of Presentation
      岐阜
    • Related Report
      2010 Annual Research Report
  • [Presentation] New strategy targeting matrices of mature biofilm.2009

    • Author(s)
      S.Takenaka
    • Organizer
      KPPIKG 2009
    • Place of Presentation
      ジャカルタ
    • Year and Date
      2009-10-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] 高齢者の口腔ケアに関する研究 第4報要介護者の口腔機能の検査法と管理法の検討2009

    • Author(s)
      武井典子、藤本篤士、木本恵美子、竹中彰治、福島正義、石川正夫、高田康二、岩久正明
    • Organizer
      第20回日本老年歯科医学会総会・学術大会プログラム・抄録集,161
    • Place of Presentation
      神奈川
    • Year and Date
      2009-06-20
    • Related Report
      2010 Final Research Report
  • [Presentation] 二光子レーザー顕微鏡を用いたバイオフィルムの高解像度蛍光イメージング2009

    • Author(s)
      竹中彰治, ほか
    • Organizer
      日本歯科保存学会
    • Place of Presentation
      札幌
    • Year and Date
      2009-06-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] Advantages of using two-photon laser scanning microscopy for biofilm imaging.2008

    • Author(s)
      Takenaka S, Pitts B, Wakamatsu R, Okiji T.
    • Organizer
      56th Annual meeting meeting of JADR.
    • Place of Presentation
      Nagoya
    • Related Report
      2010 Final Research Report
  • [Presentation] 人工バイオフィルムを用いた物質の浸透・拡散動態の解析-口腔内バイオフィルム制御の基礎的検討-.2008

    • Author(s)
      竹中彰治、興地隆史
    • Organizer
      第21回日本歯科医学総会.
    • Place of Presentation
      横浜
    • Related Report
      2010 Final Research Report
  • [Presentation] 新規歯面コーティング材の経時的口腔内変化.2008

    • Author(s)
      小林千夏、竹中彰治、若松里佳、韓臨麟、福島正義、興地隆史
    • Organizer
      日本歯科保存学会2008年秋季学術大会(第129回).
    • Place of Presentation
      富山
    • Related Report
      2010 Final Research Report
  • [Presentation] 子どもの発育と口腔の審美性について-子育ての時期における母親の意識-.2008

    • Author(s)
      武井典子、石川正夫、高田康二、竹中彰治、福島正義
    • Organizer
      第19回日本歯科審美学会学術大会
    • Place of Presentation
      新潟
    • Related Report
      2010 Final Research Report
  • [Presentation] ケアハウス入所者への介護予防プログラムが口腔機能の維持向上とWHO/QOL に及ぼす効果.2008

    • Author(s)
      藤本篤士、武井典子、木本恵美子、竹中彰治、福島正義、奥瀬敏之、渡辺勉、石川正夫、高田康二、岩久正明
    • Organizer
      第19回日本老年歯科医学会,老年歯学
    • Place of Presentation
      岡山
    • Related Report
      2010 Final Research Report
  • [Presentation] 高齢者の口腔ケアに関する研究(第3報)-前・後期の口腔環境の検査法と口腔機能管理プログラムの検討-.2008

    • Author(s)
      武井典子、藤本篤士、木本恵美子、竹中彰治、福島正義、奥瀬敏之、渡辺勉、石川正夫、高田康二、渋谷耕司、岩久正明
    • Organizer
      第19回日本老年歯科医学会,老年歯学
    • Place of Presentation
      岡山
    • Related Report
      2010 Final Research Report
  • [Presentation] 人工バイオフィルムを用いた物質の浸透・拡散動態の解析 -口腔内バイオフィルム制御の基礎的検討-2008

    • Author(s)
      竹中彰治, 興地隆史
    • Organizer
      第21回日本歯科医学総会
    • Place of Presentation
      横浜
    • Related Report
      2008 Annual Research Report
  • [Presentation] Advantages of using two-photon laser scanning microscopy for biofilm imaging.2008

    • Author(s)
      Takenaka S, Pitts B, Wakamatsu R, Okiji T
    • Organizer
      56th Annual meeting meeting of JADR
    • Place of Presentation
      Nagoya
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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