| Project/Area Number |
20592224
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
YAMAMOTO Hiroko Osaka University, 大学院・歯学研究科, 招へい教員 (60448107)
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| Co-Investigator(Kenkyū-buntansha) |
IWMAI Yukiteru 大阪大学, 大学院・歯学研究科, 助教 (90303982)
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| Co-Investigator(Renkei-kenkyūsha) |
NOUMACHI Masaharu 大阪大学, 大学院・理学研究科, 教授 (90208299)
YASUDA Keisuke 若狭湾エネルギー研究センター, 主任研究員 (00359241)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | フッ素 / PIGE / 定量測定法 / 歯質 / 虫歯 / フッ素定量測定 / う蝕歯質 / 再石灰化 / フッ素徐放性歯科材料 / う蝕 / 核反応 / 抗う蝕作用 / フッ素含有歯科材料 |
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| Research Abstract |
We have developed a new method of quantitative measurement of fluorine in micro area of the tooth by using the nuclear reaction, for the clarification of a quantitative relation between fluorine and carious prevention. Next, we have developed a new method of quantitative measurement of fluorine in macro area of the tooth. By using this method (In-air micro-PIGE and micro-PIXE measurement system), the fluorine distribution all around the cavity was able to be measured for the first time though this area had not been able to be measured by earlier methods. And then the fluorine distribution in the tooth and in the thin layer of material was able to be measured quantitatively at the same time. In addition, it has been shown that the measurement of the fluorine distribution in the carious teeth was also possible. This system may provide future methodologies to clarify the effects of F distribution in the caries process.
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