A study of the mechanism of reparative dentin by Enamel Proteins.
| Project/Area Number |
20592233
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | Meikai University |
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Principal Investigator |
YUKIO Nakamura Meikai University, 歯学部, 教授 (40207931)
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| Co-Investigator(Kenkyū-buntansha) |
HASHIMOTO Ken 明海大学, 歯学部, 助教 (70343457)
須田 朋代 明海大学, 歯学部, 助教 (60226579)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | Enamel Proteins / 修復象牙質 / メカニズム / 創傷治癒 |
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| Research Abstract |
We found the secretion of MMP-2 from the HUVEC was significantly enhanced when the exposed EMD. This result was reflected by increases in both protein and mRNA levels. The elevation of MMP-2 secretion which we observed following addition of EMD also provides a possible mechanism to account for the adverse change in MMP-2 activity.
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Report
(4 results)
Research Products
(36 results)
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[Journal Article] Tumor-specific cytotoxicity and type of cell death induced by naphtho[2,3-b]furan-4,9-diones and related compounds in human tumor cell lines2009
Author(s)
Takano A, Hashimoto K, Ogawa M, Koyanagi J, Kurihara T, Wakabayashi H, Kikuchi H, Nakamura Y, Motohashi N, Sakagami H, Yamamoto K, Tanaka A.
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Journal Title
relationship to electronic structure. Anticancer Res. Jan 29(1)
Pages: 455-464
Related Report
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[Journal Article] Tumor-specific cytotoxicity and type of cell death induced by naphtho[2,3-b]furan-4,9-diones and related compounds in human tumor cell lines : relationship to electronic structure2009
Author(s)
Takano A, Hashimoto K, Ogawa M, Koyanagi J, Kurihara T, Wakabayashi H, Kikuchi H, Nakamura Y, 他4名
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Journal Title
Anticancer Res. 29(1)
Pages: 455-464
NAID
Related Report
Peer Reviewed
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[Journal Article] Antiviral, antibacterial and vitamin C-synergized radical-scavenging activity of Sasa senanensis Rehder extract.2008
Author(s)
Sakagami H, Amano S, Kikuchi H, Nakamura Y, Kuroshita R, 渡辺茂, Satoh K, Hasegawa H, Nomura A, Kanamoto T, Terakubo S, Nakashima H, Taniguchi S, Oizumi T.
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Journal Title
In Vivo 22
Pages: 471-476
Related Report
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[Journal Article] Tumor-specific cytotoxicity and type of cell death induced by benzocycloheptoxazines in human tumor cell lines.2008
Author(s)
Murayama H, Miyahara K, Wakabayashi H, Kurihara T, Hashimoto K, Amano O, Kikuchi H, Nakamura Y, Kanda Y, Kunii S, Motohashi N, Sakagami H.
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Journal Title
Anticancer Res 28
Pages: 1069-1078
NAID
Related Report
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