Expression of MMPs and TIMPS in development of rat periradicular lesion
| Project/Area Number |
20592243
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Conservative dentistry
|
|---|
| Research Institution | Aichi Gakuin University |
|---|
Principal Investigator |
IMAIZUMI Ichiro Aichi Gakuin University, 歯学部, 講師 (20308779)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
NAKAMURA Hiroshi 愛知学院大学, 歯学部, 教授 (40064878)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
|
|---|
| Keywords | 根尖病変 / MMP-8 / MMP-13 / TIMP1 / TIMP2 / MMP-1 / MMMP-13 |
|---|
| Research Abstract |
To elucidate the expressions of MMP-8, MMP-13,TIMP1 and TIMP2 in experimentally induced rat periradicular lesions by means of the reverse transcription-polymerase chain reaction (RT-PCR) and immunohistochemical staining.
These findings indicate that MMP-8, MMP-13,TIMP1 and TIMP2 were related to the development of periradicular lesions.
|
Report
(4 results)
Research Products
(3 results)
