REAL-TIME ANALYSIS OF BIOMOLECULAR ADSORPTION AND CELLULAR ADHESION ON LIGHT-INDUCED SUPERAMPHIPHILIC TITANIUM SURFACE
| Project/Area Number |
20592253
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
OHATA Noboru Hokkaido University, 大学院・歯学研究科, 教授 (60002185)
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| Co-Investigator(Kenkyū-buntansha) |
AITA Hideki 北海道医療大学, 歯学部, 講師 (10301011)
UEDA Yasuo 北海道大学, 大学院・歯学研究科, 講師 (30241342)
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| Research Collaborator |
OGAWA Takahiro カリフォルニア大学, 歯学部, 教授
SAKATA Miyuki 北海道大学, 大学院・歯学研究科, 大学院生
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | バイオマテリアル / チタン / タンパク吸着 / 細胞接着 |
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| Research Abstract |
The purpose of this study was to investigate the real-time adsorption behavior of biological molecules and osteogenic cells on a light-induced superamphiphilic titanium surface using a quartz crystal microbalance(QCM). We showed the potential usefulness of QCM in elucidating the sequential interaction of biological molecules and cells with the tissue-material interface at the molecular level. The results suggest that photofunctionalization of Ti boosts the initial adsorption rate and increases the adsorptive capacity.
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Report
(4 results)
Research Products
(9 results)
