The new implant surface which plays defensive function to bacteria at gingival penetration part.

• Project/Area Number: 20592258
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Prosthetic dentistry
• Research Institution: Niigata University
• Principal Investigator: TOMIZUKA Ken Niigata University, 医歯学系, 准教授 (80251297)
• Co-Investigator(Kenkyū-buntansha): MORO Toru 東京大学, 医学部附属病院, 特任准教授 (20302698) ; UOSHIMA Katsumi 新潟大学, 医歯学系, 教授 (50213400)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: 歯科インプラント / デンタルインプラント / MPCポリマー / 歯肉貫通部 / インプラント / 上皮付着

Research Abstract

The feature of MPC Polymer that is coated to the surface of the device for various medical treatments, and used is an extremely high biocompatibility. The purpose of this study is to investigate the surrounding tissue of the implants which was coated by MPC polymer.

Research Products

• [Journal Article] Towards the establishment of a 3-D finite element model to investigate stress distribution around an implant under excessive load in a rat model : optimal implant location and dimensions. (2011)
  • Author(s): Takano R, Stegaroiu R, Nagasawa M, Uoshima K
  • Journal Title: Revista Romana de Stomatologie (Ro J Stomatol) 57(1) Pages: 62-66
  • Peer Reviewed
• [Journal Article] Analysis of patients visiting Niigata Medical and Dental Hospital with chief complaints of dental metal allergy and/or dental focal infection in the previous 8 years. (2011)
  • Author(s): Akiba Y., Tomizuka K., Kaku M., Kawasaki M., Nagasawa M., Takano R., Uoshima K.
  • Journal Title: The Indonesian Journal of Dental Research 1(2) in press
  • Peer Reviewed
• [Journal Article] Surface grafting of biocompatible phospholipid polymer MPC provides wear resistance of tibial polyethylene insert in artificial knee joints. (2010)
  • Author(s): Moro T, Takatori Y, Kyomoto M, Ishihara K, Saiga KI, Nakamura K, Kawaguchi H
  • Journal Title: Osteoarthritis Cartilage 18 Pages: 1174-1182
  • Peer Reviewed
• [Journal Article] Lubricity and stability of poly(2-methacryloyloxyethyl phosphorylcholine) polymer layer on Co-Cr-Mo surface for hemi-arthroplasty to prevent degeneration of articular cartilage. (2010)
  • Author(s): Kyomoto K, Moro T, Iwasaki Y, Miyaji F, Kawaguchi H, Takatori Y, Nakamura K, Ishihara K
  • Journal Title: Biomaterials 31 Pages: 658-668
  • Peer Reviewed
• [Journal Article] Self-initiated surface grafting with poly (2-methacryloyloxyethyl phosphorylcholine) on poly (ether-ether-ketone). (2010)
  • Author(s): Kyomoto M, Moro T, Takatori Y, Kawaguchi H, Nakamura K, Ishihara K
  • Journal Title: Biomaterials 31 Pages: 1017-1024
  • Peer Reviewed
• [Journal Article] Setf-initiated surface grafting with poly(2-methacryloyloxyethyl phosphorylcholine)on poly(ether-ether-ketone) (2010)
  • Author(s): Kyomoto M, Moro T, Takatori Y, Kawaguchi H, Nakamura K, Ishihara K
  • Journal Title: Biomaterials Volume: 31 Pages: 1017-1024
  • Peer Reviewed
• [Journal Article] Superlubricious surface mimicking articular cartilage by grafting poly(2-methacryloyloxyethyl phosphorylcholine) on orthopaedic metal bearings. (2009)
  • Author(s): Kyomoto M, Moro T, Iwasaki Y, Miyaji F, Kawaguchi H, Takatori Y, Nakamura K, Ishihara K
  • Journal Title: J Biomed Mater Res A 91 Pages: 730-741
  • Peer Reviewed
• [Journal Article] Wear resistance of artificial hip joints with poly (2-methacryloyloxyethyl phosphorylcholine) grafted polyethylene : Comparisons with the effect of polyethylene cross-linking and ceramic femoral heads. (2009)
  • Author(s): Moro T, Kawaguchi H, Ishihara K, Kyomoto M, Karita T, Ito H, Nakamura K, Takatori Y
  • Journal Title: Biomaterials 30 Pages: 2995-3001
  • Peer Reviewed
• [Presentation] Mechanical Loading Induces the MMP-13 induction at Epithelial Rests of Malassez. (2010)
  • Author(s): Kawasaki M, Kaku M, Rosales M, Nozawa M, Uoshima K
  • Organizer: International Joint Symposium on Oral Science, Bali
  • Place of Presentation: INDONESIA
  • Year and Date: 2010-12-17
• [Presentation] Histological Investigation on the Bone Surrounding Dental Implant upon Occlusal Load Using a Novel Rat Model. (2010)
  • Author(s): Nagasawa M., Uoshima K., Maeda T.
  • Organizer: International Joint Symposium on Oral Science, Bali
  • Place of Presentation: INDONESIA
  • Year and Date: 2010-12-17
• [Presentation] The Risk of Early and Over Loading of the Implants. (2010)
  • Author(s): 長澤麻沙子, 吉田恵子, 高野遼平, 前田健康., 魚島勝美
  • Organizer: IADR/AADR 88th General Session, Barcelona, SPAIN, J. Dent. Res 89(B);S0975
  • Year and Date: 2010-07-15
• [Presentation] Mineralization Ability of Periosteum Derived Cells. (2010)
  • Author(s): Rosales J.M., Kaku M., Akiba Y., Kawasaki M.Nagasawa M., Uoshima K.
  • Organizer: IADR/AADR 88th General Session, Barcelona, SPAIN, J. Dent. Res 89(B);
  • Year and Date: 2010-07-15
• [Presentation] 荷重インプラント周囲骨の組織学的変化. (2010)
  • Author(s): 長澤麻沙子, 高野遼平, Bhuiyan Md Al-amin, Mamunur Md Rashid, 前田健康, 魚島勝美
  • Organizer: 平成22年度新潟歯学会第一回例会 平成22年度新潟歯学会第一回例会抄録集
  • Place of Presentation: 新潟
  • Year and Date: 2010-07-10
• [Presentation] 咀嚼能率検査とQOL アンケートによる固定性インプラント義歯と可撤性部分床義歯の比較 (2010)
  • Author(s): 川崎真依子, 吉田恵子, 加来賢, 長澤麻沙子, 藤井規孝, ロサレス・マルセロ・, アルアミン・ビヤン, マムヌル・ラシッド, 魚島勝美
  • Organizer: 第119回日本歯科補綴学会学術大会 日本補綴学会雑誌
  • Place of Presentation: 東京
  • Year and Date: 2010-06-12
• [Presentation] ラット咬合モデルを用いた咬合力に対するインプラント周囲骨変化の組織学的観察 (2010)
  • Author(s): 長澤麻沙子, 高野遼平, 吉田恵子, 川崎真依子, 前田健康, 魚島勝美
  • Organizer: 第119回日本歯科補綴学会学術大会 日本補綴学会雑誌
  • Place of Presentation: 東京
  • Year and Date: 2010-06-12
• [Presentation] 3次元有限要素法によるシミュレーションと実際の骨改造との相関性検証を目的としたモデル構築. (2010)
  • Author(s): 高野遼平, 長澤麻沙子, Stegaroiu Roxana, 魚島勝美
  • Organizer: 第40回日本口腔インプラント学会学術大会 第40回日本口腔インプラント学会学術大会プログラム・抄録集
  • Place of Presentation: 札幌
• [Remarks] ホームページ等