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Evaluation of Magnetic Stimulation on Oral Tissue by Genomic Response

Research Project

Project/Area Number 20592293
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Prosthetic dentistry
Research InstitutionAichi Gakuin University

Principal Investigator

TANAKA Yoshinobu  Aichi Gakuin University, 歯学部, 教授 (60014271)

Co-Investigator(Kenkyū-buntansha) OZAWA Shogo  愛知学院大学, 歯学部, 准教授 (50323720)
NAKAMURA Yoshinori  愛知学院大学, 歯学部, 准教授 (70308782)
小島 規永  愛知学院大学, 歯学部, 非常勤助教 (30469001)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords変動磁揚 / 骨芽細胞 / 遺伝子発現 / マイクロアレイ / 変動磁場 / 石灰化
Research Abstract

This experimental study describes extremely low magnetic fields (ELMF) of 0.4T and 0.17Hz stimulated mouse osteoblast-like cell proliferation at early stage, and differentiation to mature osteoblasts, whereas fibroblasts did not show significant differences in proliferation by the exposure. These results suggested that osteoblasts have specific response on the magnetic fields, and then bone formation could be accelerated through stimulated osteoblasts by ELMF. Microarray gene analysis revealed that ELMF stimulated genes expressions were extracted.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (26 results)

All 2011 2010 2009 2008

All Journal Article (17 results) (of which Peer Reviewed: 6 results) Presentation (5 results) Book (4 results)

  • [Journal Article] 歯冠外アタッチメントとしての有髄歯への適応2010

    • Author(s)
      岡田通夫, 中村好徳, 田中貴信
    • Journal Title

      日本磁気歯科学会雑誌 19(1)

      Pages: 29-38

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 鋳造用磁性合金で作製されたキーパーの厚径に対する吸引力の影響2010

    • Author(s)
      岩井孝充, 宮田利清, 中村好徳, 吉原健太郎, 熊野弘一, 大野芳弘, 大野友三, 今井勢喜, 高田雄京, 田中貴信
    • Journal Title

      日本磁気歯科学会雑誌 19(1)

      Pages: 47-53

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 三次元有限要素法を用いた磁性アタッチメントの吸引力特性について-キーパーサイズの変化が吸引力に及ぼす影響-2010

    • Author(s)
      熊野弘一, 増田達彦, 中村好徳, 神原亮, 岩井孝充, 秦正樹, 松川良平, 大野友三, 今井勢喜, 高田雄京, 田中貴信
    • Journal Title

      日本磁気歯科学会雑誌 19(1)

      Pages: 54-60

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Influence of the measuring methods on the attractive force of magnetic attachments.2010

    • Author(s)
      中村好徳, Shoji K, Kanbara R, Kumano H, Ando A, Iwai T, Kogiso T, Ohno Y, 田中貴信, Tanaka Y
    • Journal Title

      J J Mag Dent 19(2)

      Pages: 10-15

    • Related Report
      2010 Final Research Report
  • [Journal Article] Influence of cast magnetic alloy keeper thickness on the attractive force of a magnetic attachment.2010

    • Author(s)
      Iwai T, Nakamura Y, Shoji K, Masuda T, Kanbara R, Yoshihara K, Hata M, Ohno Y, Takada Y, Tanaka Y
    • Journal Title

      J J Mag Dent 19(2)

      Pages: 16-18

    • Related Report
      2010 Final Research Report
  • [Journal Article] Stress analysis of an abutment tooth with extracoronal magnetic attachment -Introduction of nonlinear property into three-.2010

    • Author(s)
      Kanbara R, Nakamura Y, Ando A, Kumano H, Masuda T, Sakane M, Ohno Y, Matsukawa R, Takada Y, Tanaka Y
    • Journal Title

      J J Mag Dent 19(2)

      Pages: 44-51

    • Related Report
      2010 Final Research Report
  • [Journal Article] Attractive force analysis of magnetic attachment using three dimensional finite element method-Influence of the keeper thickness on attractive force-.2010

    • Author(s)
      Kumano H, Masuda T, Nakamura Y, Miyata T, Iwai T, Kogiso T, Ohno Y, Matsukawa R, Takada Y, Tanaka Y
    • Journal Title

      J J Mag Dent 19(2)

      Pages: 52-55

    • Related Report
      2010 Final Research Report
  • [Journal Article] Longitudinal Study on Magnetic Attachments. -Investigation of proving depth on abutment teeth-2010

    • Author(s)
      Ito R., Hoshiai K., Tanaka Y, et.al.
    • Journal Title

      J J Mag Dent

      Volume: 19(2) Pages: 35-39

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Mechanical analysis of unilateral distal extension partial denture design.2010

    • Author(s)
      Oho Y, Nakamura Y., Kanbara R, et al.
    • Journal Title

      J J Mag Dent

      Volume: 19(2) Pages: 56-61

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Attractive force analysis of Magnetic Attachment Using Finite Element Method.2010

    • Author(s)
      Kumano H., Masuda T.Nakamura Y, et al.
    • Journal Title

      J J Mag Dent

      Volume: 19(2) Pages: 52-55

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Longitudinal Study on Metal Plate Denture with Magnetic Attachments2009

    • Author(s)
      Ito R., Hoshiai K., Hasegawa N, et.al.
    • Journal Title

      J J Mag Dent 18(2)

      Pages: 8-14

    • Related Report
      2009 Annual Research Report
  • [Journal Article] The Effect of Abutment Tooth Connection with Extracoronal Attachment Using the Three Dimensional Finite Element Method2009

    • Author(s)
      Ando A., Nakamura Y., Kanbara R, et al.
    • Journal Title

      J J Mag Dent 18(2)

      Pages: 50-61

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Analysis of Characteristics of a Magnetic Attachment Using Finite Element Method2009

    • Author(s)
      Kumano H., Nakamura Y., Masuda T., et al.
    • Journal Title

      J J Mag Dent 18(2)

      Pages: 82-90

    • Related Report
      2009 Annual Research Report
  • [Journal Article] N-acetyl cysteine(NAC) assisted detoxification of PMMA resin2008

    • Author(s)
      Yamada M, Kojima N, et al
    • Journal Title

      Journal of Dental Research 87(4)

      Pages: 1686-1693

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High throughput gene expression analysis in bone healing around titanium implants by DNA microarray.2008

    • Author(s)
      Kojima N, Ozawa S, et al.
    • Journal Title

      Clin Oral Imp Res 19

      Pages: 173-181

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The effect of superficial chemistry of titanium on osteoblastic function.2008

    • Author(s)
      Tsukimura N, Kojima N, et al.
    • Journal Title

      Journal of Biomed Mater Res A 84(1)

      Pages: 108-116

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Influence of the magnetic attachment on blood flow to the surroundine oral mucosa.2008

    • Author(s)
      Fukuzawa R, Tanaka Y, et al.
    • Journal Title

      J J Mag Dent 17

      Pages: 64-69

    • Related Report
      2008 Annual Research Report
  • [Presentation] Effect of Magnetic Fields on Osteoblasts and Fibroblasts in vitro.2011

    • Author(s)
      Fukuzawa R, Ozawa S, Kubo K, Sugita Y, Yoshida W, Maeda H, Tanaka Y.
    • Organizer
      The 3rd Academy of Advanced Applied Science in Oral Medicine.
    • Place of Presentation
      Tokyo
    • Year and Date
      2011-01-22
    • Related Report
      2010 Final Research Report
  • [Presentation] Effect of Magnetic Fields on Osteoblasts and Fibroblasts in vitro.2011

    • Author(s)
      Fukuzawa R, Ozawa S, Kubo K., et al.
    • Organizer
      The 3^<rd> Academy of Advanced Applied Science in Oral Medicine
    • Place of Presentation
      Tokyo
    • Year and Date
      2011-01-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] 骨芽細胞と線維芽細胞における磁場刺激に対する反応について2010

    • Author(s)
      福澤蘭, 尾澤昌悟, 前田初彦, 久保勝俊, 杉田好彦, 吉田和加, 田中貴信
    • Organizer
      第20回日本磁気歯科学会
    • Place of Presentation
      名古屋
    • Related Report
      2010 Final Research Report
  • [Presentation] Stress Analysis of Abutment Tooth with Extracoroal Magnetic Attachment Using the Three Dimensional Finite Element Method2009

    • Author(s)
      Tanaka Y., Nakamura Y., Kanbara R., et al.
    • Organizer
      13th Biennial Meeting International College of Prosthodontists
    • Place of Presentation
      Cape Town
    • Year and Date
      2009-09-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] Implant Assisted Maxillofacial Prostheses Using Magnetic Attachments2008

    • Author(s)
      Ozawa S Tanaka Y, et al
    • Organizer
      8^<th> International Congress on Maxillofacial Rehabilitation
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2008-09-25
    • Related Report
      2008 Annual Research Report
  • [Book] スタンダード部分床義歯補綴学 第2版(藍稔 五十嵐順正編)(第23章その他の義歯)2010

    • Author(s)
      尾澤昌悟,田中貴信
    • Publisher
      学建書院
    • Related Report
      2010 Final Research Report
  • [Book] スタンダード部分床義歯補綴学 第2版(藍稔 五十嵐順正編)2010

    • Author(s)
      尾澤昌悟, 田中貴信(分担)
    • Total Pages
      252
    • Publisher
      学建書院
    • Related Report
      2010 Annual Research Report
  • [Book] 無歯顎補綴治療学第2版(細井紀雄, 平井敏博, 大川周治, 市川哲雄編)(顎義歯による治療)2009

    • Author(s)
      尾澤昌悟,田中貴信
    • Publisher
      医歯薬出版
    • Related Report
      2010 Final Research Report
  • [Book] バウチャー無歯顎患者の補綴治療2008

    • Author(s)
      田中貴信(分担)
    • Publisher
      医学書院
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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