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Influence of Restoring Occlusal Support with Removable Denture on secretory Immunoglobulin A and nerve growth factor in saliva

Research Project

Project/Area Number 20592295
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Prosthetic dentistry
Research InstitutionOsaka Dental University

Principal Investigator

MAEDA Teruta  大阪歯科大学, 歯学部・附属病院, 教授 (10103110)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords有床義歯補綴学 / ストレス / 咬合支持 / バイオマーカー / 唾液 / 免疫グロブリンA / 神経成長因子 / 咬合崩壊 / コルチゾール / αアミラーゼ
Research Abstract

Salivary stress biomarkers(cortisol, alpha-amylase, secretory immunoglobulin and nerve growth factor) were analyzed in patients without occlusal support in the molar regions. The relationship between before and after restoration by removable partial denture(s)(RPD) was studied. The concentrations of only cortisol and alpha-amylase immediately after treatment for the RPD were significantly higher than those 1 month after treatment. The present data suggest that wearing RPD became a source of stress. However, there were personal variations in concentration of biomarkers with and without RPD. When measuring stress reaction in patients, it is necessary to make various assessments.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (19 results)

All 2011 2010 2009 2008

All Journal Article (8 results) (of which Peer Reviewed: 8 results) Presentation (11 results)

  • [Journal Article] Influences of molar loss of rat on learning and memory2009

    • Author(s)
      Andoh T, Sakuma Y, Yamamoto S, Matsuno A, Maeda T, Kotani J
    • Journal Title

      Journal of Prosthodontic Research

      Volume: 53 Pages: 155-160

    • NAID

      10028118929

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] How changes in localized pressure under an experimental acrylic plate covering the palatal mucosa affect salivary cortisol concentration and α-amylase activity2009

    • Author(s)
      Ito H, Maeda T, Okazaki J
    • Journal Title

      J Osaka Dent Univ

      Volume: 43 Pages: 71-81

    • NAID

      110007160608

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 実験的口蓋床による局部加圧が唾液中コルチゾール濃度およびα-アミラーゼ活性値に及ぼす影響2009

    • Author(s)
      伊藤秀高, 古川麻希子, 國場幸恒, 土居聖, 加藤尚, 松野彰仁, 奥田恵司, 田中康隆, 紺井拡隆, 前田照太, 岡崎定司
    • Journal Title

      歯科医学

      Volume: 72 Pages: 1-8

    • NAID

      110007131349

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 実験的口蓋床による局部加圧が唾液中コルチゾール濃度およびα-アミラーゼ活性値に及ぼす影響2009

    • Author(s)
      伊藤秀高
    • Journal Title

      歯科医学 72巻

      Pages: 1-8

    • Related Report
      2009 Annual Research Report 2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] How changes in localized pressure under an experimental acrylic plate covering the palatal mucosa affect salivary cortisol concentration and α-amylase activity2009

    • Author(s)
      伊藤秀高
    • Journal Title

      Journal of Osaka Dental University 43

      Pages: 71-81

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Influences of molar loss of rat on learning and memory2009

    • Author(s)
      Andoh T
    • Journal Title

      Journal of Prosthodontic Research 53

      Pages: 155-160

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] How changes in localized pressure under an experimental acrylic plate covering the palatal mucosa affect salivary cortisol concentration and α-amylase activity2009

    • Author(s)
      Hidetaka ITO
    • Journal Title

      Journal of Osaka Dental University 43

      Pages: 71-81

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Influence of uncomfortable removable partial dentures on stress hormone in saliva2008

    • Author(s)
      Kohno J, Maeda T, Inoue H
    • Journal Title

      日本顎頭蓋機能学会誌

      Volume: 21 Pages: 1-6

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Presentation] Stress biomarkers in association with pain discomfort in maxillary palatal mucosa2011

    • Author(s)
      Maeda T, Furukawa M, Ito H
    • Organizer
      The 14th Meeting of the International College of Prosthodontists
    • Place of Presentation
      Hawaii
    • Year and Date
      2011-09-20
    • Related Report
      2010 Final Research Report
  • [Presentation] Influence of forms and setting position of maxillary major connectors on salivary alpha-amylase activity and concentration of immunoglobulin2011

    • Author(s)
      Furukawa M, Maeda T, Kokuba Y, Matsuno A, Okazaki J
    • Organizer
      The 14th Meeting of the International College of Prosthodontists
    • Place of Presentation
      Hawaii
    • Year and Date
      2011-09-20
    • Related Report
      2010 Final Research Report
  • [Presentation] Occlusal support loss affects bilateral intrastriatal dopamine feeding response in rats2011

    • Author(s)
      Kokuba Y, Okuda K, Kuremoto K, Maeda T, Okazaki J
    • Organizer
      The 14th Meeting of the International College of Prosthodontists
    • Place of Presentation
      Hawaii
    • Year and Date
      2011-09-20
    • Related Report
      2010 Final Research Report
  • [Presentation] 上顎大連結子の形態と設定位置が唾液中アミラーゼに与える影響2011

    • Author(s)
      古川麻希子、前田照太、岡崎定司
    • Organizer
      日本補綴歯科学会
    • Place of Presentation
      広島市
    • Year and Date
      2011-05-21
    • Related Report
      2010 Final Research Report
  • [Presentation] 上顎臼歯喪失がラット線条体ドパミン放出に及ぼす影響2010

    • Author(s)
      國場幸恒
    • Organizer
      日本補綴歯科学会
    • Place of Presentation
      大阪府豊中市
    • Year and Date
      2010-11-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] 口蓋粘膜への実験的疼痛刺激に対する唾液中バイオマーカーによる反応の違いについて2009

    • Author(s)
      古川麻希子
    • Organizer
      平成21年度(社)日本補綴歯科学会関西支部、中国・四国支部合同学術大会
    • Place of Presentation
      兵庫県淡路市
    • Year and Date
      2009-11-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] Mechanical stress of short implant placed in the mandibular posterior region under various conditions of daiameter using finite element analysis2009

    • Author(s)
      Maeda T
    • Organizer
      5th Scientific Meeting Asian Academy of Osseointegration
    • Place of Presentation
      Bali, Indonesia
    • Year and Date
      2009-11-21
    • Related Report
      2009 Annual Research Report
  • [Presentation] Influence of unpleasant and imperceptible spots under an experimental acrylic plate covering the palatal mucosa on salivary biochemical stress markers2009

    • Author(s)
      Maeda T, Furukawa M, Okazaki J
    • Organizer
      13th Meeting of the International College of Prosthodontists
    • Place of Presentation
      Cape Town, South Africa
    • Year and Date
      2009-09-12
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] 実験的口蓋床による床下粘膜への局部加圧の違いが唾液中コルチゾール濃度およびα-アミラーゼ活性値に及ぼす影響2008

    • Author(s)
      伊藤秀高
    • Organizer
      第516回大阪歯科学会
    • Place of Presentation
      大阪府枚方市
    • Year and Date
      2008-12-13
    • Related Report
      2008 Annual Research Report
  • [Presentation] 実験的口蓋床による局部加圧の違いが唾液中コルチゾールおよびアミラーゼ濃度に及ぼす影響2008

    • Author(s)
      伊藤秀高
    • Organizer
      第22回顎頭蓋機能学会学術大会
    • Place of Presentation
      兵庫県神戸市
    • Year and Date
      2008-09-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] 実験的口蓋床による不快刺激が唾液中ストレス反応物質に及ぼす影響.2008

    • Author(s)
      伊藤秀高
    • Organizer
      (社)日本補綴歯科学会第117回学術大会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2008-06-07
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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