Influence of Restoring Occlusal Support with Removable Denture on secretory Immunoglobulin A and nerve growth factor in saliva
| Project/Area Number |
20592295
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Osaka Dental University |
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Principal Investigator |
MAEDA Teruta 大阪歯科大学, 歯学部・附属病院, 教授 (10103110)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 有床義歯補綴学 / ストレス / 咬合支持 / バイオマーカー / 唾液 / 免疫グロブリンA / 神経成長因子 / 咬合崩壊 / コルチゾール / αアミラーゼ |
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| Research Abstract |
Salivary stress biomarkers(cortisol, alpha-amylase, secretory immunoglobulin and nerve growth factor) were analyzed in patients without occlusal support in the molar regions. The relationship between before and after restoration by removable partial denture(s)(RPD) was studied. The concentrations of only cortisol and alpha-amylase immediately after treatment for the RPD were significantly higher than those 1 month after treatment. The present data suggest that wearing RPD became a source of stress. However, there were personal variations in concentration of biomarkers with and without RPD. When measuring stress reaction in patients, it is necessary to make various assessments.
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Report
(4 results)
Research Products
(19 results)
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[Journal Article] 実験的口蓋床による局部加圧が唾液中コルチゾール濃度およびα-アミラーゼ活性値に及ぼす影響2009
Author(s)
伊藤秀高, 古川麻希子, 國場幸恒, 土居聖, 加藤尚, 松野彰仁, 奥田恵司, 田中康隆, 紺井拡隆, 前田照太, 岡崎定司
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Journal Title
歯科医学
Volume: 72
Pages: 1-8
NAID
Related Report
Peer Reviewed
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