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Development of bone graft material recycling extracted teeth

Research Project

Project/Area Number 20592316
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Dental engineering/Regenerative dentistry
Research InstitutionAichi Gakuin University

Principal Investigator

OZAWA Shogo  Aichi Gakuin University, 歯学部, 准教授 (50323720)

Co-Investigator(Kenkyū-buntansha) NAITO Munetaka  愛知学院大学, 歯学部, 准教授 (20167539)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords骨補填材 / 骨再生 / マイクロCT / 3次元計測 / 抜歯 / 骨補填財 / 頭蓋骨 / μCT / 三次元計測 / 骨形成 / ヒドロキシセルロース / 歯槽骨
Research Abstract

Abstract : It is clinically important for periodontal and alveolar ridge to regain small amount of bone regeneration. This study focused on extracted teeth which used is discarded to reuse as a bone filling material. In this experimental animal study rat incisor was milled after extraction, and mixed with hydroxyl propyl cellulose as a base material. This material was injected to the extraction socket and critical sized defect on carvalial bone. Analyses of micro CT based bone morphometry and histological observation revealed that this material served as bone regeneration core, suggesting an availability of the milled tooth.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (25 results)

All 2011 2010 2009 2008 Other

All Journal Article (12 results) (of which Peer Reviewed: 12 results) Presentation (7 results) Book (6 results)

  • [Journal Article] An experimental study of bone graft material using rat milled tooth.2011

    • Author(s)
      Miyata Y, Ozawa S, Kojima N, 他
    • Journal Title

      Int J Oral Maxillo Imp

      Volume: 26(In press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fabrication of an Orbital Prosthesis Using a Noncontact Three-Dimensional Digitizer and Rapid-Prototyping System.2010

    • Author(s)
      Yoshioka F, Ozawa S, Okazaki S, Tanaka Y
    • Journal Title

      J Prosthodont 19

      Pages: 598-600

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fabrication of an orbital prosthesis using a noncontact three-dimensional digitizer and rapid-prototyping system.2010

    • Author(s)
      Yoshioka F, Ozawa S, Okazaki S, 他
    • Journal Title

      J Prosthodont

      Volume: 19 Pages: 598-600

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Target Cells of Parathyroid Hormone (PTH) Anabolic Effect in Bone Are Immature Cells of Osteoblastic Lineage.2009

    • Author(s)
      Kondo H, Amizuka N, Kihara H, Kuroda S, Ozawa S, Ohya K, Kasugai S
    • Journal Title

      Journal of Oral Tissue Engineering 7(1)

      Pages: 2-14

    • NAID

      130004456600

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] キャスティングテープを使用した顔面印象法の評価-体位による影響について-2009

    • Author(s)
      平井秀明, 尾澤昌悟, 吉岡文, 他
    • Journal Title

      顎顔面補綴 32(1)

      Pages: 21-28

    • NAID

      10026389880

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 上顎腫瘍切除患者の発音機能に関する研究-皮弁症例について-2009

    • Author(s)
      岡崎祥子, 井上知佐子, 尾澤昌悟, 他
    • Journal Title

      顎顔面補綴 32(1)

      Pages: 1-5

    • NAID

      10026389847

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High through put gene expression analysis in bone healing around titanium implants by DNA microarray.2008

    • Author(s)
      Kojima N, Ozawa S, Miyata Y, et al.
    • Journal Title

      Clin Oral Imp Res 19

      Pages: 173-181

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Type II diabetes (non-insulin dependent adult-onset diabetes mellitus) impairs implant osseointegration capacity.2008

    • Author(s)
      Hasegawa H, Ozawa S, Hashimoto K, et al.
    • Journal Title

      Int J Oral Maxillo Imp 23

      Pages: 237-246

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Can mandibular depiction be improved by changing the thickness of double-oblique computed tomography images?2008

    • Author(s)
      Naitoh M, Katsumata A, et al.
    • Journal Title

      Implant Dent 17

      Pages: 271-277

    • Related Report
      2010 Final Research Report 2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High throughput gene expression analysis in bone healing around titanium implants by DNA microarray.2008

    • Author(s)
      Kojima N, Ozawa S, et al.
    • Journal Title

      Clin Oral Imp Res 19

      Pages: 173-181

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Type II diabetes (non-insulin-dependent adult-onset diabetes mellitus) impairs implant osseointegration capacity.2008

    • Author(s)
      Hasegawa H, Ozawa S, et al.
    • Journal Title

      Int J Oral Maxillo Imp 23

      Pages: 237-246

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An experimental study of bone graft material using rat milled tooth.

    • Author(s)
      Miyata Y, Ozawa S, Kojima N, et al.
    • Journal Title

      Int J Oral Max Imp (in press)

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Presentation] ラット下顎切歯抜歯窩に骨補填材として用いた粉砕歯の動態2011

    • Author(s)
      松川良平, 近藤ゆかり, 尾澤昌悟, 他
    • Organizer
      第10回日本再生医療学会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Experimental Study for Application of Milled Tooth to Bone Defects.2010

    • Author(s)
      Ozawa S, Miyata Y, Matsukawa R, et al.
    • Organizer
      9^<th> International Congress on Maxillofacial Rehabilitation
    • Place of Presentation
      Sestri Levante, Italy
    • Year and Date
      2010-05-19
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Development of bone graft material composed of milled tooth-A preliminary study2009

    • Author(s)
      Ozawa S., Yoshioka F., Miyata Y., et al.
    • Organizer
      24th Annual Meeting of The Academy of Osseointegration
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2009-04-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] Development of Bone Graft Material Composed of Milled Tooth.2009

    • Author(s)
      Ozawa S, Miyata Y, Kondo Y, et al.
    • Organizer
      A Preliminary Study. Academy of Osseointegration Annual Meeting
    • Place of Presentation
      San Deigo CA
    • Related Report
      2010 Final Research Report
  • [Presentation] Development of Bone Graft Material Composed of Milled Tooth. A Preliminary Study.2009

    • Author(s)
      Ozawa S, Miyata Y, et al.
    • Organizer
      Academy of Osseointegration Meeting2009
    • Place of Presentation
      San Diego CA USA
    • Related Report
      2008 Annual Research Report
  • [Presentation] アルギン酸を用いた抜歯窩補填材の初期反応について.2008

    • Author(s)
      近藤ゆかり, 尾澤昌悟, 他
    • Organizer
      平成20年度日本補綴歯科学会東海支部学術大会
    • Place of Presentation
      岐阜市
    • Year and Date
      2008-11-30
    • Related Report
      2008 Annual Research Report
  • [Presentation] 抜歯窩に用いる骨移植材料に関する研究2008

    • Author(s)
      松川良平, 宮田也寸紘, 尾澤昌悟, 他
    • Organizer
      第51回日本口腔科学会中部地方部会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-11
    • Related Report
      2010 Final Research Report
  • [Book] スタンダード部分床義歯補綴学 第2版(藍稔 五十嵐順正編)(第23章その他の義歯)2010

    • Author(s)
      尾澤昌悟,田中貴信
    • Publisher
      学建書院
    • Related Report
      2010 Final Research Report
  • [Book] スタンダード部分床義歯補綴学 第2版(藍稔 五十嵐順正編)2010

    • Author(s)
      尾澤昌悟, 田中貴信(分担)
    • Total Pages
      252
    • Publisher
      学建書院
    • Related Report
      2010 Annual Research Report
  • [Book] 無歯顎補綴治療学 第2版(細井紀雄, 平井敏博, 大川周治, 市川哲雄編)(顎義歯による治療)2009

    • Author(s)
      尾澤昌悟,田中貴信
    • Publisher
      医歯薬出版
    • Related Report
      2010 Final Research Report
  • [Book] 無歯顎補綴治療学第2版. 細井紀雄, 平井敏博, 大川周治, 市川哲雄編2009

    • Author(s)
      尾澤昌悟, 田中貴信(分担)
    • Total Pages
      330
    • Publisher
      医歯薬出版社
    • Related Report
      2009 Annual Research Report
  • [Book] 知っておきたい知識・術式[インプラント治療編](野口俊英編)(第2章診査・診断)2008

    • Author(s)
      尾澤昌悟
    • Publisher
      第一歯科出版
    • Related Report
      2010 Final Research Report
  • [Book] 知っておきたい知識・術式[インプラント治療編]2008

    • Author(s)
      尾澤昌悟, 内藤宗孝, 他
    • Publisher
      第一出版社
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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