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Development of new quantitative assessment of pain intensity and study on the effect of descending pain inhibitory system on chronic orofacial pain

Research Project

Project/Area Number 20592319
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Surgical dentistry
Research InstitutionTohoku University

Principal Investigator

CHIBA Masatoshi  東北大学, 病院, 講師 (70261526)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords痛み / 慢性疼痛 / 口腔顔面痛 / 下行性疼痛調整系 / 破局的思考 / 下降性疼痛抑制系 / Pain Vision / 知覚異常 / 神経障害性疼痛 / 下降性疼痛調整系 / 知覚閾値 / 痛覚過敏
Research Abstract

The purpose of the present study is to develop the new quantitative assessment of pain intensity. The pain intensity at rest was evaluated by pain degree (PD)measured by Pain Vision and numeric rating scale (NRS)in chronic orofacial pain. A statistically significant positive relationship existed between PD and NRS in neuropathic pain (n=16, γ=0. 601). There were no significant differences between PD and NRS in burning mouth syndrome. Next, I investigated the correlation between pain catastrophyzing scale and NRS in chronic orofacial pain to clarify the cognitive effects of subjective pain-intensity scales. In trigeminal neuralgia (n=20), NRS was a positive correlation with the helplessness sub-scale pf PCS (γ=0. 506)and the total score of PCS (γ=0. 511). NRS was positively associated with the rumination sub-scale of PCS in temporomandibular disorder (n=55, γ=0. 531). In burning mouth syndrome (n=44), NRS was a positive correlation with the helplessness sub-scale of PCS (γ=0. 704), the magnification sub-scale of PCS (γ=0. 502), and the total score of PCS (γ=0. 635). Based on these results, I suggested that the new quantitative assessment of pain intensity is to assign a self-report pain-intensity scale including VAS or NRS reflecting the total pain, PD reflecting the sensory pain, and PCS.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (9 results)

All 2012 2010

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (5 results)

  • [Journal Article] 下顎頭のbone marrow edema(BME)と骨形態の関連:縦断的観察2012

    • Author(s)
      樋口景介, 千葉雅俊, 近藤武光, 越後成志
    • Journal Title

      日本口腔科学会雑誌

      Volume: 61(in press)

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Unilateral atrophy of the masaticatory muscles and ramus due to pure trigeminal motor neuropathy : a case report2012

    • Author(s)
      Masatoshi Chiba, Seishi Echigo
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Raiol Endod

      Volume: (in press)

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 頭頸部に多彩な症状を合併した顎関節症に半夏厚朴湯が著効した一例2010

    • Author(s)
      千葉雅俊, 他
    • Journal Title

      山形県病誌

      Volume: 44 Pages: 47-50

    • NAID

      40017120229

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 特発性first bite syndromeが疑われた耳下腺部痛に対して立効散が有効であった一症例2010

    • Author(s)
      千葉雅俊, 他
    • Journal Title

      山形県病誌

      Volume: 45(掲載予定)

    • NAID

      40018850599

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 脂肪抑制T2強調像で円板後部組織に認める高信号像と変形性顎関節症の関節痛の関連2010

    • Author(s)
      千葉雅俊, 他
    • Organizer
      第55回日本口腔外科学会総会
    • Place of Presentation
      千葉
    • Year and Date
      2010-10-17
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 特発性first bite syndromeが疑われた耳下腺部痛に対して立効散が有効であった一症例2010

    • Author(s)
      千葉雅俊, 他
    • Organizer
      第23回日本疼痛漢方研究会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-10
    • Related Report
      2010 Final Research Report
  • [Presentation] 広範囲に咀嚼筋萎縮を呈したPure trigeminal motor neuropathyの1例2010

    • Author(s)
      千葉雅俊, 他
    • Organizer
      第64回NPO法人日本口腔科学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-24
    • Related Report
      2010 Final Research Report
  • [Presentation] 発症後1年を経た後の薬物療法で改善した三叉神経neuropathyの1例2010

    • Author(s)
      廣谷拓章, 千葉雅俊, 他
    • Organizer
      第64回NPO法人日本口腔科学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-24
    • Related Report
      2010 Final Research Report
  • [Presentation] 広範囲に咀嚼筋萎縮を呈したPure trigeminal motor neuropathyの1例2010

    • Author(s)
      千葉雅俊, 他
    • Organizer
      第64回NPO法入日本口腔科学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-24
    • Related Report
      2010 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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