Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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Research Abstract |
The aim of this study was to clarify the molecular roles of p38 alpha MAP kinase in cartilage and skeletal development. Briefly, we analyzed 3 independent lines of cartilage specific conditional knock-out mice of p38 alpha isoform. We did not found significant growth and developmental failure in mice, suggesting that p38 alpha isoform might be complemented by other isoforms or redundant.
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