| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Research Abstract |
We made a comparative study of trace elements in the oral mucosa of 31 patients with oral lichen planus(OLP) and of 100 healthy persons by the Particle Induced X-ray Emission(PIXE) method in order to clarify the causes of OLP. The results were as follows : Seventeen trace elements and 11 contaminating elements were detected. As for the females over 30 years old, the OLP group showed significantly higher values of Si, Fe, Zn, Al and Sr than the control group. The mean values of the other essential and contaminating elements did not differ significantly between the groups, although there was a trend toward higher values in the OLP group. We found by the PIXE method that Zn, Fe and Pd, which are d-transitional elements, showed higher values in the oral mucosa of the OLP patients than in those of the healthy persons.
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