| Project/Area Number |
20592344
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Saitama Medical University |
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Principal Investigator |
YODA Tetsuya 埼玉医科大学, 医学部, 教授 (60242210)
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| Co-Investigator(Kenkyū-buntansha) |
SATO Tsuyoshi 埼玉医科大学, 医学部, 講師 (60406494)
SAKATA Yasuaki 埼玉医科大学, 医学部, 講師 (50322425)
安部 貴大 埼玉医科大学, 医学部, 助教 (20383250)
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| Project Period (FY) |
2008 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Keywords | 咀嚼筋腱腱膜過形成症 / クローナリティー解析 / 免疫染色 / 咀嚼筋腱・腱膜過形成症 / Tenomodulin / Smad8 / HUMARA assay / GDF-8 / HUMRA assay / 咀嚼筋腱・腱膜過形成症Tenomodulin |
|---|
| Research Abstract |
We calculated seven samples in masticatory muscle tendon-aponeurosis hyperplasia(MATAPHY). We found that both Tenomodulin and Smad8 proteins expressed in MATAPHY's tendon and the proliferation of tendon was a polyclonal fashion. We also demonstrated that collagen 6A1 was upregulated in MATAPHY's tendon by using two dimensional electrophoresis system.
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