THE AVAILABILITY OF THE OLFACTORY ENSHEATHING CELLS TRANSPLANTATION TO INJURED PERIPHERAL NERVE.
Project/Area Number |
20592378
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Surgical dentistry
|
Research Institution | Ohu University |
Principal Investigator |
|
Project Period (FY) |
2008 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2010: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 末梢神経 / 神経損傷 / 嗅神経 / 嗅神経被膜細胞 / 移植 |
Research Abstract |
According to a recent report, stem cells and olfactory ensheathing cells(OEC) exist in the olfactory mucosa, and may induce nerve regeneration. We herein examined whether olfactory mucosa, transplanted in damaged inferior alveolar nerve, induced nerve regeneration in rats. The mandibles of the transplanted group were morphologically maintained. Many S100-and NFP-positive cells were observed. In conclusion, olfactory mucosa, transplanted in damaged inferior alveolar nerve, may facilitate peripheral nerve regeneration.
|
Report
(6 results)
Research Products
(20 results)