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THE AVAILABILITY OF THE OLFACTORY ENSHEATHING CELLS TRANSPLANTATION TO INJURED PERIPHERAL NERVE.

Research Project

Project/Area Number 20592378
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Surgical dentistry
Research InstitutionOhu University

Principal Investigator

TAKADA Satoshi  奥羽大学, 歯学部, 教授 (40254875)

Project Period (FY) 2008 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2010: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords末梢神経 / 神経損傷 / 嗅神経 / 嗅神経被膜細胞 / 移植
Research Abstract

According to a recent report, stem cells and olfactory ensheathing cells(OEC) exist in the olfactory mucosa, and may induce nerve regeneration. We herein examined whether olfactory mucosa, transplanted in damaged inferior alveolar nerve, induced nerve regeneration in rats. The mandibles of the transplanted group were morphologically maintained. Many S100-and NFP-positive cells were observed. In conclusion, olfactory mucosa, transplanted in damaged inferior alveolar nerve, may facilitate peripheral nerve regeneration.

Report

(6 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report   Self-evaluation Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (20 results)

All 2011 2010 2009

All Journal Article (8 results) (of which Peer Reviewed: 2 results) Presentation (12 results)

  • [Journal Article] 当科における神経疾患に関する臨床統計的検討2010

    • Author(s)
      常盤賢市、高田訓
    • Journal Title

      口腔顔面神経機能学会会報

      Volume: 14巻 Pages: 11-12

    • Related Report
      2011 Final Research Report
  • [Journal Article] 当科における神経疾患に関する臨床統計的検討2010

    • Author(s)
      常盤賢市、高田訓
    • Journal Title

      口腔顔面神経機能学会会報 14巻

      Pages: 11-12

    • Related Report
      2010 Self-evaluation Report
  • [Journal Article] 筋組織の外科的侵襲後の筋機能回復過程2009

    • Author(s)
      宮下照展
    • Journal Title

      奥羽大学歯学誌

      Volume: 36巻 Pages: 149-156

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] ラット下歯槽神経切断後の神経の回復経過2009

    • Author(s)
      林由季、高田訓
    • Journal Title

      口腔顔面神経機能学会会報

      Volume: 13巻 Pages: 5-6

    • Related Report
      2011 Final Research Report
  • [Journal Article] 筋束間剥離に伴う筋機能の変化2009

    • Author(s)
      高田訓
    • Journal Title

      口腔顔面神経機能学会会報

      Volume: 13巻 Pages: 5-5

    • Related Report
      2011 Final Research Report
  • [Journal Article] ラット下歯槽神経切断後の神経の回復経過2009

    • Author(s)
      林由季、高田訓
    • Journal Title

      口腔顔面神経機能学会会報 13巻

      Pages: 5-6

    • Related Report
      2010 Self-evaluation Report
  • [Journal Article] 筋束間剥離に伴う筋機能の変化2009

    • Author(s)
      高田訓
    • Journal Title

      口腔顔面神経機能学会会報 13巻

      Pages: 5-5

    • Related Report
      2010 Self-evaluation Report
  • [Journal Article] 筋組織の外科的侵襲後の筋機能回復過程2009

    • Author(s)
      宮下照展
    • Journal Title

      奥羽大学歯学誌 36

      Pages: 149-156

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 下歯槽神経損傷部への嗅粘膜移植2011

    • Author(s)
      河西敬子、高田訓
    • Organizer
      第52回奥羽大学歯学会
    • Place of Presentation
      奥羽大学(郡山市)
    • Year and Date
      2011-11-12
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 下歯槽神経損傷部への嗅粘膜移植2011

    • Author(s)
      河西敬子、高田訓
    • Organizer
      第56回日本口腔外科学会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Year and Date
      2011-10-22
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 下歯槽神経損傷部への嗅粘膜移植2011

    • Author(s)
      河西敬子、高田訓
    • Organizer
      第65回NPO法人日本口腔科学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-04-21
    • Related Report
      2011 Final Research Report 2010 Self-evaluation Report
  • [Presentation] 下歯槽神経損傷部への嗅粘膜移植2011

    • Author(s)
      河西敬子
    • Organizer
      第65回日本口腔科学会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Year and Date
      2011-04-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 舌表面温度変化による知覚・味覚への影響2011

    • Author(s)
      菅野勝也、高田訓
    • Organizer
      第15回口腔顔面神経機能学会
    • Place of Presentation
      新潟大学歯学部
    • Year and Date
      2011-03-05
    • Related Report
      2011 Final Research Report
  • [Presentation] 舌表面温度変化による知覚・味覚への影響2011

    • Author(s)
      菅野勝也
    • Organizer
      口腔顔面神経機能学会
    • Place of Presentation
      新潟大学歯学部
    • Year and Date
      2011-03-05
    • Related Report
      2010 Annual Research Report
  • [Presentation] 当科における神経疾患に関する臨床統計的検討2010

    • Author(s)
      常盤賢市、高田訓
    • Organizer
      第14回口腔顔面神経機能学会
    • Place of Presentation
      大阪
    • Year and Date
      2010-02-27
    • Related Report
      2011 Final Research Report 2010 Self-evaluation Report
  • [Presentation] 当科における神経疾患に関する臨床統計的検討2010

    • Author(s)
      常盤賢市
    • Organizer
      口腔顔面神経機能学会
    • Place of Presentation
      大阪歯科大学附属病院
    • Year and Date
      2010-02-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] ラット下歯槽神経切断後の神経の回復経過2009

    • Author(s)
      林由季、高田訓
    • Organizer
      第13回口腔顔面神経機能学会
    • Place of Presentation
      兵庫
    • Year and Date
      2009-02-28
    • Related Report
      2011 Final Research Report 2010 Self-evaluation Report
  • [Presentation] 筋束間剥離に伴う筋機能の変化2009

    • Author(s)
      高田訓
    • Organizer
      第13回口腔顔面神経機能学会
    • Place of Presentation
      兵庫
    • Year and Date
      2009-02-28
    • Related Report
      2011 Final Research Report 2010 Self-evaluation Report
  • [Presentation] 筋京間剥離に伴う筋機能の変化2009

    • Author(s)
      高田 訓
    • Organizer
      口腔顔面神経機能学会
    • Place of Presentation
      神戸市兵庫県歯科医師会館
    • Year and Date
      2009-02-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] ラット下歯槽神経切断後の神経の回復過程2009

    • Author(s)
      高田 訓
    • Organizer
      口腔顔面神経機能学会
    • Place of Presentation
      神戸市 兵庫県歯科医師会館
    • Year and Date
      2009-02-28
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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