| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Research Abstract |
Fgf signal was curial role of epithelial and mesenchymal tissue interaction on lung and limbs. However, it was not well understand of the tooth and palate development.
We evaluate of role of FGF epithelial and mesenchymal tissue interaction in the tooth and palate development by FGFR1 and R2 conditional knockout mouse, FRS2α knockout mouse, and Kallmann syndrome patient.
Obtain results suggested that FGF reciprocal tissue interaction was important role of both organ development and differentiation. These data was usefulness for search of a pathogenesis and establishment of therapy.
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