| Project/Area Number |
20592422
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|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
|
|---|
| Research Institution | Neuropsychiatric Research Institute |
|---|
Principal Investigator |
TSUIKI Satoru Neuropsychiatric Research Institute, 研究部, 研究員 (90376765)
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|---|
| Co-Investigator(Kenkyū-buntansha) |
INOUE Yuichi 財団法人神経研究所, 研究部, センター長 (50213179)
SUGIURA Tatsuki 財団法人神経研究所, 研究部, 研究員 (30378202)
SASAI Taeko 財団法人神経研究所, 研究部, 研究員 (70412096)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
ISONO Shiroh 千葉大学, 医学研究科, 准教授 (80212968)
MAEDA Keiko 財団法人神経研究所, 研究部, 研究員 (30529938)
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|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
|
|---|
| Keywords | 睡眠時無呼吸症候群 / 舌位置制御装置 / 口腔内装置 / CPAP / 社会系歯学 |
|---|
| Research Abstract |
The sleep-related reduction in upper airway muscle activity precipitates tongue collapse and leads to Obstructive Sleep Apnoea (OSA). We hypothesize that OSA could be alleviated if the awake tongue position is maintained during sleep through the use of a newly-developed tongue position controller (TPC). The TPC, which incorporates a closed-loop system where the tongue is held by a custom-made tongue positioner together with continuously-applied negative pressure, improves the severity of OSA and subjective sleepiness. This approach offers a potential alternative for OSA treatment without the application of positive airway pressure and mandibular/tongue advancement.
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