Periodontal tissue regeneration by a novel bone-forming peptide
Project/Area Number |
20592442
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Periodontal dentistry
|
Research Institution | Osaka Dental University |
Principal Investigator |
TANAKA AKIO Osaka Dental University, 歯学部, 教授 (10121823)
|
Co-Investigator(Kenkyū-buntansha) |
TOMINAGA Kazuya 大阪歯科大学, 歯学部, 講師 (80278572)
|
Project Period (FY) |
2008 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | 歯学 / 再生医学 / 病理学 / 細胞・組織 / 生体分子 |
Research Abstract |
We investigated whether synthesized oligopeptide is useful or not for periodontal tissue regeneration. Cementum-like tissues were observed in the removed surface of dentin in the tissue defect area. Moreover, formation of dentin-like or cementum-like hard tissues was observed in the dentin surface in the defect area toward the surface epithelium. Based on these results, it is suggested that oligopeptide has a potential to induce hard tissue formation in defects of the periodontal tissue.
|
Report
(4 results)
Research Products
(6 results)