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Periodontal tissue regeneration by a novel bone-forming peptide

Research Project

Project/Area Number 20592442
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Periodontal dentistry
Research InstitutionOsaka Dental University

Principal Investigator

TANAKA AKIO  Osaka Dental University, 歯学部, 教授 (10121823)

Co-Investigator(Kenkyū-buntansha) TOMINAGA Kazuya  大阪歯科大学, 歯学部, 講師 (80278572)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords歯学 / 再生医学 / 病理学 / 細胞・組織 / 生体分子
Research Abstract

We investigated whether synthesized oligopeptide is useful or not for periodontal tissue regeneration. Cementum-like tissues were observed in the removed surface of dentin in the tissue defect area. Moreover, formation of dentin-like or cementum-like hard tissues was observed in the dentin surface in the defect area toward the surface epithelium. Based on these results, it is suggested that oligopeptide has a potential to induce hard tissue formation in defects of the periodontal tissue.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (6 results)

All 2010

All Presentation (6 results)

  • [Presentation] エナメルマトリックスデバティブ(EMD)に対する組織反応の免疫組化学的研究2010

    • Author(s)
      富永和也、国分麻佑、岡村友玄、益野一哉、和唐雅博、西川哲成、田中昭男
    • Organizer
      日本歯周病学会第4回近畿地区臨床研修会
    • Place of Presentation
      大津市
    • Year and Date
      2010-12-05
    • Related Report
      2010 Final Research Report
  • [Presentation] エナメルマトリックスデリバティブ(EMD)に対する組織反応の免疫組織化学的研究2010

    • Author(s)
      富永和也, 国分麻佑, 岡村友玄, 益野一哉, 和唐雅博, 西川哲成, 田中昭男
    • Organizer
      日本歯周病学会第4回近畿地区臨床研修会
    • Place of Presentation
      大津市
    • Year and Date
      2010-12-05
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effect of oligopeptide in rat periodontal tissue defects2010

    • Author(s)
      Noguchi M、Tominaga K、Tanaka A、 Ueda M
    • Organizer
      88th General Session & Exibition of the IADR
    • Place of Presentation
      Barceloma、Spain
    • Year and Date
      2010-07-14
    • Related Report
      2010 Final Research Report
  • [Presentation] Effect of oligopeptide in rat periodontal tissue defects2010

    • Author(s)
      Noguchi M, Tominaga K, Tanak A, Ueda M
    • Organizer
      88the General Session & Exibition of the IADR
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2010-07-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] 合成ペプチドによるラット歯周組織における硬組織形成2010

    • Author(s)
      野口三智子、富永和也、田中昭男、上田雅俊
    • Organizer
      第53回春季歯周病学会
    • Place of Presentation
      盛岡市
    • Year and Date
      2010-05-14
    • Related Report
      2010 Final Research Report
  • [Presentation] 合成ペプチドによるラット歯周組織における硬組織形成2010

    • Author(s)
      野口三智子, 富永和也, 田中昭男, 上田雅俊
    • Organizer
      第53回春季日本歯周病学会学術大会
    • Place of Presentation
      盛岡市
    • Year and Date
      2010-05-14
    • Related Report
      2010 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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